Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

American Journal of Physiology - Cell Physiology

Volumn 297, Issue 4, 2009, Pages

  Tew, Simon R ^a   Peffers, Mandy J ^a   McKay, Tristan R ^b   Lowe, Emma T ^c   Khan, Wasim S ^c   Hardingham, Timothy E ^c   Clegg, Peter D ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Actin; COL2A1; mRNA stability; Osmolarity; p38 mitogen activated protein kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN COL2A1; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL ISOLATION; CONTROLLED STUDY; DIFFERENTIATION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HALF LIFE TIME; HUMAN; HUMAN CELL; HYPEROSMOLALITY; OSMOTIC PRESSURE; OSTEOARTHRITIS; PRIORITY JOURNAL; REGULATORY MECHANISM; REPRODUCIBILITY; STRESS FIBER; TRANSCRIPTION REGULATION; UPREGULATION;

ACTINS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; HUMANS; OSMOLAR CONCENTRATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; SOX9 TRANSCRIPTION FACTOR;

EID: 70349934709     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00571.2008     Document Type: Article

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