Dental stem cells and their potential role in apexogenesis and apexification

International Endodontic Journal

Volumn 42, Issue 11, 2009, Pages 955-962

  Friedlander, L T ^a   Cullinan, M P ^a   Love, R M ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Apexification; Apexogenesis; Dental stem cells; Growth factors; Immature permanent teeth; Regeneration; Root development

Indexed keywords

GROWTH PROMOTOR;

ARTICLE; CYTOLOGY; ENDODONTICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METHODOLOGY; PERIODONTAL LIGAMENT; PHYSIOLOGY; REGENERATION; STEM CELL; TOOTH PAPILLA; TOOTH PULP; TOOTH ROOT;

APEXIFICATION; DENTAL PAPILLA; DENTAL PULP; GROWTH SUBSTANCES; HUMANS; PERIODONTAL LIGAMENT; REGENERATION; STEM CELLS; TOOTH APEX;

EID: 70349880881     PISSN: 01432885     EISSN: 13652591     Source Type: Journal    
DOI: 10.1111/j.1365-2591.2009.01622.x     Document Type: Article

References (68)

1. Antoniou M. (2001) Embryonic stem cell research: the case against. Nature Medicine 7, 397 399.
2. Banchs F, Trope M (2004) Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? Journal of Endodontics 30, 196 200.
3. Chen SC, Marino V, Gronthos S, Bartold PM (2006) Location of putative stem cells in human periodontal ligament. Journal of Periodontal Research 41, 547 553.
4. Chueh LH, Huang GT (2006) Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis: a paradigm shift. Journal of Endodontics 32, 1205 1213.
5. Cordeiro MM, Dong Z, Kaneko T, et al. (2008) Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth. Journal of Endodontics 34, 962 969.
6. Denholm A, Moule AJ, Bartold PM (1998) The behavior and proliferation of human dental pulp cell strains in vitro, and their response to the application of platelet-derived growth factor-BB and insulin-like growth factor-1. International Endodontic Journal 31, 251 258.
7. Dobie K, Smith G, Sloan AJ, Smith AJ (2002) Effects of alginate hydrogels and TGF-β 1 on human dental pulp repair in vitro. Connective Tissue Research 43, 387 390.
8. Friedenstein AJ, Piatetzy-Shapiro II, Petrakova KV (1966) Osteogenesis in transplants of bone marrow cells. Journal of Embryology and Experimental Morphology 16, 381 390.
9. Gebhardt M, Murray PE, Namerow KN, Kuttler S, Garcia-Godoy F (2009) Cell survival within pulp and periodontal constructs. Journal of Endodontics 35, 63 6.
10. Gomez Flores M, Hasegawa M, Yamoto M, Takagi R, Okano T, Ishikawa I (2008) Cementum-periodontal ligament complex regeneration using the cell sheet technique. Journal of Periodontal Research 43, 364 371.
11. + fraction of adult human bone marrow contains the osteogenic precursors. Blood 84, 4164 4173.
12. Gronthos S, Mankani M, Brahim J, Gehron Robey P, Shi S (2000) Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America 97, 13625 13630.
13. Gronthos S, Brahim J, Li W, et al. (2002) Stem cell properties of human dental pulp stem cells. Journal of Dental Research 81, 531 535.
14. Gronthos S, Zannettino ACW, Hay SJ, et al. (2003) Molecular and cellular characterization of highly purified stromal stem cells derived from human bone marrow. Journal of Cell Science 116, 1827 1835.
15. Hachmeister DR, Schindler WG, Walker WA, Thomas DD (2002) The sealing ability and retention characteristics of mineral trioxide aggregate in a model of apexification. Journal of Endodontics 28, 386 390.
16. Handa K, Saito M, Tsunoda A, et al. (2002) Progenitor cells from the dental follicle are able to form cementum matrix in vivo. Connective Tissue Research 43, 406 408. (Pubitemid 34784577)
17. Howell T, Fiorellini J, Paquette D, Offenbacher S, Giannobile W, Lynch S (1997) A phase I/II clinical trial to evaluate a combination of recombinant human platelet derived growth factor-BB and recombinant human insulin-like growth factor-1 in patients with periodontal disease. Journal of Periodontology 68, 1186 1193.
18. Huang GT, Sonoyama W, Chen J, Park SH (2006) In vitro characterization of human dental pulp cells: various isolation methods and culturing environments. Cell Tissue Research 324, 225 236.
19. Huang AH, Chen Y, Lin L, Shieh T, Chan AW (2008) Isolation and characterization of dental pulp stem cells from a supernumery tooth. Journal of Oral Pathology and Medicine 37, 571 574.
20. Iohara K, Nakashima M, Ito M, Ishikawa M, Nakasima A, Akamine A (2004) Dentin regeneration by dental pulp stem cell therapy with recombinant human bone morphogenic protein 2. Journal of Dental Research 83, 590 595.
21. Jin QM, Anusaksathien O, Webb SA, Rutherford RB, Giannobile WV (2003) Gene therapy of bone morphogenic protein for periodontal tissue engineering. Journal of Periodontology 74, 202 213.
22. Jung IY, Lee SJ, Hargreaves KM (2008) Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series. Journal of Endodontics 34, 876 887.
23. Kémoun P, Laurencin-Dalicieux S, Rue J, et al. (2007) Localization of STRO-1, BMP-2/-3/-7, BMP receptors and phosphorylated Smad-1 during the formation of mouse periodontium. Tissue and Cell 39, 257 266.
24. King GN, Hughes FJ (2001) Bone morphogenic protein-2 stimulates cell recruitment and cementogenesis during early wound healing. Journal of Clinical Periodontology 28, 465 475.
25. King GN, King N, Cruchley AT, Wozney JM, Hughs FJ (1997) Recombinant human bone morphogenic protein-2 promotes wound healing in rat periodontal fenestration defects. Journal of Dental Research 76, 1460 1470.
26. Lovschall H, Tummers M, Thesleff I, Füchtbauer EM, Poulsen K (2005) Activation of the Notch signaling pathway in response to pulp capping of rat molars. European Journal of Oral Sciences 113, 312 317.
27. McCulloch CA (1985) Progenitor cell populations in the periodontal ligament of mice. The Anatomical Record 211, 258 262.
28. McCulloch CA, Nemeth E, Lowenberg B, Melcher AH (1987) Paravascular cells in endosteal spaces of alveolar bone contribute to periodontal ligament cell populations. The Anatomical Record 219, 233 242.
29. Melcher AH (1985) Cells of the periodontium: their role in the healing of wounds. Annals of the Royal College of Surgeons of England 67, 130 131.
30. Miura M, Gronthos S, Zhao M, et al. (2003) SHED: stem cells from human exfoliated deciduous teeth. Proceedings of the National Academy of Sciences of the United States of America 100, 5807 5812.
31. Mjör IA, Dahl E, Cox CF (1991) Healing of pulp exposures: an ultrastructural study. Journal of Oral Pathology and Medicine 20, 496 501.
32. Mooney DJ, Powell C, Piana J, Rutherford B (1996) Engineering dental pulp-like tissues in vitro. Biotechnology Progress 12, 865 868.
33. Mullane EM, Dong Z, Sedgley CM, et al. (2008) Effects of VEGF and FGF2 on the revascularization of severed human dental pulps. Journal of Dental Research 87, 1144 1148.
34. Nagatomo K, Komaki M, Sekiya I, et al. (2006) Stem cell properties of human periodontal ligament cells. Journal of Periodontal Research 41, 303 310.
35. Nakashima M (1994) Induction of dentin formation on canine amputated pulp by recombinant human morphogenic proteins (BMP)-2 and -4. Journal of Dental Research 73, 1515 1522.
36. Nakashima M, Mizunuma K, Murakami T, Akamine A (2002) Induction of dental pulp stem cell differentiation into odontoblasts by electroporation-mediated gene delivery of growth/differentiation factor 11 (Gdf11). Gene Therapy 9, 814 818.
37. Nakashima M, Tachibana K, Iohara K, Ito M, Ishikawa M, Akamine A (2003) Induction of reparative dentin formation by ultrasound-mediated gene delivery of growth/differentiation factor 11. Human Gene Therapy 14, 591 597.
38. Nakashima M, Iohara K, Ishikawa M, et al. (2004) A stimulation of reparative dentin formation be ex vivo gene therapy using dental pulp stem cells electrotransfected with growth/differentiation factor 11. Human Gene Therapy 15, 1045 1053.
39. Pene JR, Nicholls JI, Harrington GW (2001) Evaluation of fibre-composite laminate in the restoration of immature nonvital maxillary central incisors. Journal of Endodontics 27, 18 22.
40. Robey PG (2000) Stem cells near the century mark. Journal of Clinical Investigation 105, 1489 1491.
41. Rutherford RB (2001) BMP-7 gene transfer to inflamed ferret dental pulps. European Journal of Oral Sciences 109, 422 424.
42. Rutherford RB, Gu K (2000) Treatment of inflamed ferret dental pulps with recombinant bone morphogenic protein-7. European Journal of Oral Sciences 108, 202 206.
43. Saito T, Ogawa M, Hata Y, Bessho K (2004) Acceleration effect of human recombinant bone morphogenic protein-2 on differentiation of human pulp cells into odontoblasts. Journal of Endodontics 30, 205 208.
44. Scheller EL, Chang J, Wang CY (2008) Wnt/β-catenin inhibits dental pulp stem cell differentiation. Journal of Dental Research 87, 126 130.
45. Seo BM, Miura M, Gronthos S, et al. (2004) Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364, 149 155.
46. Seo BM, Miura M, Sonoyama W, Coppe C, Stanyon R, Shi S (2005) Recovery of stem cells from cryopreserved periodontal ligament. Journal of Dental Research 84, 907 912.
47. Shabahang S, Torabinejad M (2000) Treatment of teeth with open apices using mineral trioxide aggregate. Practical Periodontics and Aesthetic Dentistry 12, 315 320.
48. Shi S, Gronthos S (2003) Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. Journal of Bone and Mineral Research 18, 696 704.
49. Shi S, Bartold PM, Miura M, Seo BM, Robey PG, Gronthos S (2005) The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthodontics and Crainiofacial Research 8, 191 199.
50. Sloan AJ, Rutherford RB, Smith AJ (2000) Stimulation of rat dentine-pulp complex by bone morphogenic protein-7 in vitro. Archives of Oral Biology 45, 173 177.
51. Smith AJ, Patel M, Graham L, Sloan AJ, Cooper PR (2005) Dentine regeneration: the role of stem cells and molecular signalling. Oral Biosciences and Medicine 2, 127 132.
52. Sonoyama W, Liu Y, Fang D, et al. (2006) Mesenchymal stem cell-mediated functional tooth regeneration in swine. PLoS One 1, e79. 1-8.
53. Sonoyama W, Seo BM, Yamaza T, Shi S (2007) Human Hertwig's epithelial root sheath cells play crucial roles in cementum formation. Journal of Dental Research 86, 594 599.
54. Sonoyama W, Liu Y, Yamaza T, et al. (2008) Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. Journal of Endodontics 34, 166 171.
55. Takeda T, Tezuka Y, Horiuchi M, et al. (2008) Characterization of dental pulp stem cells of human tooth germs. Journal of Dental Research 87, 676 681.
56. Ten Cate AR (1978) A fine structural study of coronal and root dentinogenesis in the mouse: observation on the so-called 'von-Korff fibres' and their contribution to mantle dentin. Journal of Anatomy 125, 183 197.
57. Ten Cate AR (1997) The development of the periodontium - a largely ectomesenchymally derived unit. Periodontology 2000 13, 9 19.
58. Thibodeau B, Teixeira F, Yamauchi M, Caplan DJ, Trope M (2007) Pulp revascularization of immature dog teeth with apical periodontitis. Journal of Endodontics 33, 680 689.
59. Thomson TS, Berry JE, Somerman MJ, Kirkwood KL (2003) Cementoblasts maintain expression of osteocalcin in the presence of mineral trioxide aggregate. Journal of Endodontics 29, 407 412.
60. Toyono T, Nakashima M, Kuhara S, Akamine A (1997) Expression of TGF-β superfamily receptors in dental pulp. Journal of Dental Research 76, 1555 1560.
61. Trowbridge HO (2003) Pulp biology: progress during the past 25 years. Australian Endodontic Journal 29, 5 12.
62. Tziafas D, Smith AJ, Lesot H (2000) Designing new strategies in vital pulp therapy. Journal of Dentistry 28, 77 92.
63. Vojinović O, Vojinović J (1993) Periodontal migration into the apical pulp during the repair process after pulpectomy in immature teeth: an autoradiographic study. Journal of Oral Rehabilitation 20, 637 652.
64. Witherspoon DE, Small JC, Regan JD, Nunn M (2008) Retrospective analysis of open apex teeth obturated with mineral trioxide aggregate. Journal of Endodontics 34, 1171 1176.
65. Yang C, Przyborski S, Cooke MJ, et al. (2008) A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation. Stem Cells 26, 850 863.
66. Young CS, Terada S, Vacanti JP, Honda M, Bartlett JD, Yelick PC (2002) Tissue engineering of complex tooth structures on biodegradable polymer scaffolds. Journal of Dental Research 81, 695 700.
67. Zhang W, Walboomers XF, Shi S, Fan M, Jansen JA (2006) Multilineage differentiation potential of stem cells derived from human dental pulp after cryopreservation. Tissue Engineering 12, 2813 2823.
68. Zhang C, Chang J, Sonoyama W, Shi S, Wang CY (2008) Inhibition of human dental pulp stem cell differentiation by Notch signaling. Journal of Dental Research 87, 250 255.