p38 MAP kinase inhibits neutrophil development through phosphorylation of C/EBPα on serine 21

Stem Cells

Volumn 27, Issue 9, 2009, Pages 2271-2282

  Geest, Christian R ^a   Buitenhuis, Miranda ^a   Laarhoven, Annemieke G ^a   Bierings, Marc B ^b   Bruin, Marrie C A ^b   Vellenga, Edo ^c   Coffer, Paul J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

C EBP ; CD34+; Hematopoiesis; Myeloid; p38MAPK; Severe congenital neutropenia

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA 2 MICROGLOBULIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 5; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SERINE 21; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CHILD; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EOSINOPHIL; GRANULOCYTE; GRANULOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; MYELOPOIESIS; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PRESCHOOL CHILD; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SCHOOL CHILD; SCID MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELLS, CULTURED; ENZYME INHIBITORS; EOSINOPHILS; HUMANS; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; MAP KINASE KINASE 3; MICE; MICE, INBRED NOD; MICE, SCID; MYELOPOIESIS; NEUTROPENIA; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PYRIDINES; RESPIRATORY BURST; SERINE;

MUS;

EID: 70349865008     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.152     Document Type: Article

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