Reduced spatial learning in mice treated with NVP-AAM077 through down-regulating neurogenesis

European Journal of Pharmacology

Volumn 622, Issue 1-3, 2009, Pages 37-44

  Hu, Mei ^b   Sun, Yong Jun ^c   Zhou, Qi Gang ^a   Auberson, Yves P ^d   Chen, Ling ^a   Hu, Yao ^a   Luo, Chun Xia ^a   Wu, Jia Yi ^a   Zhu, Dong Ya ^a   Li, Li Xin ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Neurogenesis; nNOS; NR2A; NVP AAM077; Spatial memory

Indexed keywords

[[1 (4 BROMOPHENYL)ETHYLAMINO](2,3 DIOXO 1,2,3,4 TETRAHYDROQUINOXALIN 5 YL)METHYL]PHOSPHONIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURONAL NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; HIPPOCAMPUS; LEARNING; MAZE TEST; MITOSIS INHIBITION; MOUSE; MOUSE MUTANT; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SPATIAL MEMORY; SUBVENTRICULAR ZONE;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CEREBRAL VENTRICLES; DENTATE GYRUS; LEARNING; MALE; MEMORY; MICE; NEUROGENESIS; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN SUBUNITS; QUINOXALINES; RECEPTORS, N-METHYL-D-ASPARTATE; SPATIAL BEHAVIOR; STEM CELLS; SUBSTRATE SPECIFICITY;

EID: 70349862089     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.031     Document Type: Article

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