S38151 [p-guanidinobenzoyl-[Des-Gly10]-MCH(7-17)] is a potent and selective antagonist at the MCH1 receptor and has anti-feeding properties in vivo

Peptides

Volumn 30, Issue 11, 2009, Pages 1997-2007

  Audinot, Valérie ^a,b   Zuana, Odile Della ^b   Fabry, Nelly ^a   Ouvry, Christine ^a   Nosjean, Olivier ^a   Henlin, Jean Michel ^a   Fauchère, Jean Luc ^a   Boutin, Jean A ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Feeding behavior; Melanin concentrating hormone; Peptide antagonists; Rat; Receptors

Indexed keywords

4 GUANIDINOBENZOYL(10 DESGLYCINE)MELANIN CONCENTRATING HORMONE[7-17]; [10 DESGLYCINE]MELANIN CONCENTRATING HORMONE[6-17]; MELANIN CONCENTRATING HORMONE RECEPTOR 1; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; S 38151; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FOOD INTAKE; IC 50; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; FEEDING BEHAVIOR; HUMANS; HYPOTHALAMIC HORMONES; MALE; MELANINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PITUITARY HORMONES; RATS; RATS, WISTAR; RECEPTORS, PITUITARY HORMONE;

RATTUS;

EID: 70349804683     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.07.007     Document Type: Article

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