[125I]-S36057: A new and highly potent radioligand for the melanin-concentrating hormone receptor

British Journal of Pharmacology

Volumn 133, Issue 3, 2001, Pages 371-378

  Audinot, Valérie ^a   Lahaye, Chantal ^a   Suply, Thomas ^a   Beauverger, Philippe ^a   Rodriguez, Marianne ^a   Galizzi, Jean Pierre ^a   Fauchère, Jean Luc ^b   Boutin, Jean A ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

MCH; SLC 1 receptor

Indexed keywords

GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HORMONE RECEPTOR; IODINE 125; MELANIN CONCENTRATING HORMONE; PHENYLALANINE; RADIOLIGAND; S 36057; TYROSINE; UNCLASSIFIED DRUG; 3 IODOTYROSYL 8 AMINO 3,6 DIOXYOCTANOYL ARGINYL CYSTEINYL METHIONYL LEUCYL GLYCYL ARGINYL VALYL PHENYLALANYL ARGINYL PROLYL CYSTEINYLTRYPTOPHAN; 3-IODOTYROSYL-8-AMINO-3,6-DIOXYOCTANOYL-ARGINYL-CYSTEINYL-METHIONYL-LEUCYL-GLYCYL-ARGINYL-VALYL-PHENYLALANYL-ARGINYL-PROLYL-CYSTEINYLTRYPTOPHAN; CYCLIC AMP; FORSKOLIN; HYPOPHYSIS HORMONE; HYPOTHALAMUS HORMONE; LIGAND; MELANIN; MELANIN CONCENTRATING HORMONE RECEPTOR; MELANIN-CONCENTRATING HORMONE; MELANIN-CONCENTRATING HORMONE RECEPTOR; OLIGOPEPTIDE; RADIOACTIVE IODINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CHO CELL; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIODINATION; RELIABILITY; AMINO ACID SEQUENCE; ANIMAL; BRAIN; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; ENZYME SPECIFICITY; HAMSTER; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; RADIOASSAY; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CELL LINE; CELL MEMBRANE; CHO CELLS; CRICETINAE; CYCLIC AMP; FORSKOLIN; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; HYPOTHALAMIC HORMONES; IODINE RADIOISOTOPES; KINETICS; LIGANDS; MELANINS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PITUITARY HORMONES; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, PITUITARY HORMONE; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0034740233     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704085     Document Type: Article

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