-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, and J.M. Friedman Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
L.A. Campfield, F.J. Smith, Y. Guisez, R. Devos, and P. Burn Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks Science 269 1995 546 549
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
3
-
-
0030931045
-
Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta
-
N. Hoggard, L. Hunter, J.S. Duncan, L.M. Williams, P. Trayhurn, and J.G. Mercer Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta Proc. Natl. Acad. Sci. U. S. A. 94 1997 11073 11078
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 11073-11078
-
-
Hoggard, N.1
Hunter, L.2
Duncan, J.S.3
Williams, L.M.4
Trayhurn, P.5
Mercer, J.G.6
-
4
-
-
0032543680
-
A nutrient-sensing pathway regulates leptin gene expression in muscle and fat
-
J. Wang, R. Liu, M. Hawkins, N. Barzilai, and L. Rossetti A nutrient-sensing pathway regulates leptin gene expression in muscle and fat Nature 393 1998 684 688
-
(1998)
Nature
, vol.393
, pp. 684-688
-
-
Wang, J.1
Liu, R.2
Hawkins, M.3
Barzilai, N.4
Rossetti, L.5
-
5
-
-
0033798974
-
Leptin modulates extracellular matrix molecules and metalloproteinases: Possible implications for trophoblast invasion
-
M. Castellucci, R. De Matteis, A. Meisser, R. Cancello, V. Monsurro, and D. Islami Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion Mol. Hum. Reprod. 6 2000 951 958
-
(2000)
Mol. Hum. Reprod.
, vol.6
, pp. 951-958
-
-
Castellucci, M.1
De Matteis, R.2
Meisser, A.3
Cancello, R.4
Monsurro, V.5
Islami, D.6
-
6
-
-
0034918777
-
Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization
-
J.E. Reseland, U. Syversen, I. Bakke, G. Qvigstad, L.G. Eide, and O. Hjertner Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization J. Bone Miner. Res. 16 2001 1426 1433
-
(2001)
J. Bone Miner. Res.
, vol.16
, pp. 1426-1433
-
-
Reseland, J.E.1
Syversen, U.2
Bakke, I.3
Qvigstad, G.4
Eide, L.G.5
Hjertner, O.6
-
7
-
-
2442654859
-
Identification and expression cloning of a leptin receptor
-
L.A. Tartaglia, M. Dembski, X. Weng, N. Deng, J. Culpepper, and R. Devos Identification and expression cloning of a leptin receptor OB-R. Cell 83 1995 1263 1271
-
(1995)
OB-R. Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
-
8
-
-
0034714050
-
Leptin is a potent stimulator of bone growth in ob/ob mice
-
C.M. Steppan, D.T. Crawford, K.L. Chidsey-Frink, H. Ke, and A.G. Swick Leptin is a potent stimulator of bone growth in ob/ob mice Regul. Pept. 92 2000 73 78
-
(2000)
Regul. Pept.
, vol.92
, pp. 73-78
-
-
Steppan, C.M.1
Crawford, D.T.2
Chidsey-Frink, K.L.3
Ke, H.4
Swick, A.G.5
-
9
-
-
0036146459
-
Potential role of leptin in endochondral ossification
-
K. Kume, K. Satomura, S. Nishisho, E. Kitaoka, K. Yamanouchi, and S. Tobiume Potential role of leptin in endochondral ossification J. Histochem. Cytochem. 50 2002 159 169
-
(2002)
J. Histochem. Cytochem.
, vol.50
, pp. 159-169
-
-
Kume, K.1
Satomura, K.2
Nishisho, S.3
Kitaoka, E.4
Yamanouchi, K.5
Tobiume, S.6
-
10
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
C.T. Montague, I.S. Farooqi, J.P. Whitehead, M.A. Soos, H. Rau, and N.J. Wareham Congenital leptin deficiency is associated with severe early-onset obesity in humans Nature 387 1997 903 908
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
-
11
-
-
0033304576
-
Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects
-
M. Ozata, I.C. Ozdemir, and J. Licinio Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects J. Clin. Endocrinol. Metab. 84 1999 3686 3695
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 3686-3695
-
-
Ozata, M.1
Ozdemir, I.C.2
Licinio, J.3
-
12
-
-
0021747962
-
Mouse mutants as models in endocrine research
-
H.M. Charlton Mouse mutants as models in endocrine research Q. J. Exp. Physiol. 69 1984 655 676
-
(1984)
Q. J. Exp. Physiol.
, vol.69
, pp. 655-676
-
-
Charlton, H.M.1
-
13
-
-
0033575993
-
Effects of recombinant leptin therapy in a child with congenital leptin deficiency
-
I.S. Farooqi, S.A. Jebb, G. Langmack, E. Lawrence, C.H. Cheetham, and A.M. Prentice Effects of recombinant leptin therapy in a child with congenital leptin deficiency N. Engl. J. Med. 341 1999 879 884
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 879-884
-
-
Farooqi, I.S.1
Jebb, S.A.2
Langmack, G.3
Lawrence, E.4
Cheetham, C.H.5
Prentice, A.M.6
-
14
-
-
0029806309
-
Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development
-
K. Lee, B. Lanske, A.C. Karaplis, J.D. Deeds, H. Kohno, and R.A. Nissenson Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development Endocrinology 137 1996 5109 5118
-
(1996)
Endocrinology
, vol.137
, pp. 5109-5118
-
-
Lee, K.1
Lanske, B.2
Karaplis, A.C.3
Deeds, J.D.4
Kohno, H.5
Nissenson, R.A.6
-
15
-
-
0346963598
-
MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
-
T.H. Vu, J.M. Shipley, G. Bergers, J.E. Berger, J.A. Helms, and D. Hanahan MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes Cell 93 1998 411 422
-
(1998)
Cell
, vol.93
, pp. 411-422
-
-
Vu, T.H.1
Shipley, J.M.2
Bergers, G.3
Berger, J.E.4
Helms, J.A.5
Hanahan, D.6
-
16
-
-
0034962273
-
The perichondrium plays an important role in mediating the effects of TGF-beta1 on endochondral bone formation
-
J. Alvarez, J. Horton, P. Sohn, and R. Serra The perichondrium plays an important role in mediating the effects of TGF-beta1 on endochondral bone formation Dev. Dyn. 221 2001 311 321
-
(2001)
Dev. Dyn.
, vol.221
, pp. 311-321
-
-
Alvarez, J.1
Horton, J.2
Sohn, P.3
Serra, R.4
-
17
-
-
0036166701
-
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
C. Maes, P. Carmeliet, K. Moermans, I. Stockmans, N. Smets, and D. Collen Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188 Mech. Dev. 111 2002 61 73
-
(2002)
Mech. Dev.
, vol.111
, pp. 61-73
-
-
Maes, C.1
Carmeliet, P.2
Moermans, K.3
Stockmans, I.4
Smets, N.5
Collen, D.6
-
18
-
-
0031992120
-
New method for genotyping the mouse Lep(ob) mutation, using a polymerase chain reaction assay
-
M. Namae, Y. Mori, K. Yasuda, T. Kadowaki, Y. Kanazawa, and K. Komeda New method for genotyping the mouse Lep(ob) mutation, using a polymerase chain reaction assay Lab. Anim. Sci. 48 1998 103 104
-
(1998)
Lab. Anim. Sci.
, vol.48
, pp. 103-104
-
-
Namae, M.1
Mori, Y.2
Yasuda, K.3
Kadowaki, T.4
Kanazawa, Y.5
Komeda, K.6
-
19
-
-
0031575804
-
Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization
-
N. Hoggard, J.G. Mercer, D.V. Rayner, K. Moar, P. Trayhurn, and L.M. Williams Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization Biochem. Biophys. Res. Commun. 232 1997 383 387
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.232
, pp. 383-387
-
-
Hoggard, N.1
Mercer, J.G.2
Rayner, D.V.3
Moar, K.4
Trayhurn, P.5
Williams, L.M.6
-
21
-
-
0038715713
-
Chondrogenic differentiation during midfacial development in the mouse: In vivo and in vitro studies
-
M.I. Pavlov, J.M. Sautier, M. Oboeuf, A. Asselin, and A. Berdal Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies Biol. Cell 95 2003 75 86
-
(2003)
Biol. Cell
, vol.95
, pp. 75-86
-
-
Pavlov, M.I.1
Sautier, J.M.2
Oboeuf, M.3
Asselin, A.4
Berdal, A.5
-
22
-
-
18044385800
-
Cunningham, in vitro differentiation profile of osteoblasts derived from patients with Saethre-Chotzen syndrome
-
C. Ratisoontorn, M.L. Seto, and K.M. Broughton Cunningham, In vitro differentiation profile of osteoblasts derived from patients with Saethre-Chotzen syndrome Bone 36 2005 627 634
-
(2005)
Bone
, vol.36
, pp. 627-634
-
-
Ratisoontorn, C.1
Seto, M.L.2
Broughton, K.M.3
-
23
-
-
0025338661
-
A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells
-
T. Atsumi, Y. Miwa, K. Kimata, and Y. Ikawa A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells Cell Differ. Dev. 30 1990 109 116
-
(1990)
Cell Differ. Dev.
, vol.30
, pp. 109-116
-
-
Atsumi, T.1
Miwa, Y.2
Kimata, K.3
Ikawa, Y.4
-
24
-
-
0029875398
-
Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: Differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
-
C. Shukunami, C. Shigeno, T. Atsumi, K. Ishizeki, F. Suzuki, and Y. Hiraki Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor J. Bone Miner. Res. 133 1996 457 468
-
(1996)
J. Bone Miner. Res.
, vol.133
, pp. 457-468
-
-
Shukunami, C.1
Shigeno, C.2
Atsumi, T.3
Ishizeki, K.4
Suzuki, F.5
Hiraki, Y.6
-
25
-
-
0030788922
-
Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro
-
C. Shukunami, K. Ishizeki, T. Atsumi, Y. Ohta, F. Suzuki, and Y. Hiraki Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro J. Bone Miner. Res. 12 1997 1174 1188
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 1174-1188
-
-
Shukunami, C.1
Ishizeki, K.2
Atsumi, T.3
Ohta, Y.4
Suzuki, F.5
Hiraki, Y.6
-
26
-
-
0034042572
-
Associations of leptin with body fat distribution and metabolic parameters in non-insulin-dependent diabetic patients: No effect of apolipoprotein e polymorphism
-
M. Wauters, R. Considine, A. Lofgren, C. Van Broeckhoven, J.C. Van der Auwera, and I. De Leeuw Associations of leptin with body fat distribution and metabolic parameters in non-insulin-dependent diabetic patients: no effect of apolipoprotein E polymorphism Metabolism 49 2000 724 730
-
(2000)
Metabolism
, vol.49
, pp. 724-730
-
-
Wauters, M.1
Considine, R.2
Lofgren, A.3
Van Broeckhoven, C.4
Van Der Auwera, J.C.5
De Leeuw, I.6
-
28
-
-
0035999436
-
Leptin acts as a growth factor on the chondrocytes of skeletal growth centers
-
G. Maor, M. Rochwerger, Y. Segev, and M. Phillip Leptin acts as a growth factor on the chondrocytes of skeletal growth centers J. Bone Miner. Res. 17 2002 1034 1043
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 1034-1043
-
-
Maor, G.1
Rochwerger, M.2
Segev, Y.3
Phillip, M.4
-
29
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
-
P. Ducy, M. Amling, S. Takeda, M. Priemel, A.F. Schilling, and F.T. Beil Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 2000 197 207
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
-
30
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
S. Takeda, F. Elefteriou, R. Levasseur, X. Liu, L. Zhao, and K.L. Parker Leptin regulates bone formation via the sympathetic nervous system Cell 111 2002 305 317
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
-
31
-
-
0033625473
-
Binding of a pure 125I-monoiodoleptin analog to mouse tissues: A developmental study
-
C. Dal Farra, N. Zsurger, J.P. Vincent, and A. Cupo Binding of a pure 125I-monoiodoleptin analog to mouse tissues: a developmental study Peptides 21 2000 577 587
-
(2000)
Peptides
, vol.21
, pp. 577-587
-
-
Dal Farra, C.1
Zsurger, N.2
Vincent, J.P.3
Cupo, A.4
-
32
-
-
0035860185
-
Human articular chondrocytes express functional leptin receptors
-
Y. Figenschau, G. Knutsen, S. Shahazeydi, O. Johansen, and B. Sveinbjornsson Human articular chondrocytes express functional leptin receptors Biochem. Biophys. Res. Commun. 287 2001 190 197
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.287
, pp. 190-197
-
-
Figenschau, Y.1
Knutsen, G.2
Shahazeydi, S.3
Johansen, O.4
Sveinbjornsson, B.5
-
33
-
-
0031764737
-
Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion
-
I. Shimon, X. Yan, D.A. Magoffin, T.C. Friedman, and S. Melmed Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion J. Clin. Endocrinol. Metab. 83 1998 4059 4064
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 4059-4064
-
-
Shimon, I.1
Yan, X.2
Magoffin, D.A.3
Friedman, T.C.4
Melmed, S.5
-
34
-
-
0027488970
-
Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition
-
O. Jacenko, P.A. LuValle, and B.R. Olsen Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition Nature 365 1993 56 61
-
(1993)
Nature
, vol.365
, pp. 56-61
-
-
Jacenko, O.1
Luvalle, P.A.2
Olsen, B.R.3
-
35
-
-
0030271579
-
Type X collagen is colocalized with a proteoglycan epitope to form distinct morphological structures in bovine growth cartilage
-
G. Gibson, D.L. Lin, K. Francki, B. Caterson, and B. Foster Type X collagen is colocalized with a proteoglycan epitope to form distinct morphological structures in bovine growth cartilage Bone 19 1996 307 315
-
(1996)
Bone
, vol.19
, pp. 307-315
-
-
Gibson, G.1
Lin, D.L.2
Francki, K.3
Caterson, B.4
Foster, B.5
-
36
-
-
0030023871
-
The demographics of slipped capital femoral epiphysis. An international multicenter study
-
R.T. Loder The demographics of slipped capital femoral epiphysis. An international multicenter study Clin. Orthop. 322 1996 8 27
-
(1996)
Clin. Orthop.
, vol.322
, pp. 8-27
-
-
Loder, R.T.1
-
37
-
-
0029746041
-
Serum leptin in children with obesity: Relationship to gender and development
-
S.G. Hassink, D.V. Sheslow, E. de Lancey, I. Opentanova, R.V. Considine, and J.F. Caro Serum leptin in children with obesity: relationship to gender and development Pediatrics 98 1996 201 203
-
(1996)
Pediatrics
, vol.98
, pp. 201-203
-
-
Hassink, S.G.1
Sheslow, D.V.2
De Lancey, E.3
Opentanova, I.4
Considine, R.V.5
Caro, J.F.6
-
38
-
-
0036234187
-
Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling
-
J.O. Gordeladze, C.A. Drevon, U. Syversen, and J.E. Reseland Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: impact on differentiation markers, apoptosis, and osteoclastic signaling J. Cell. Biochem. 85 2002 825 836
-
(2002)
J. Cell. Biochem.
, vol.85
, pp. 825-836
-
-
Gordeladze, J.O.1
Drevon, C.A.2
Syversen, U.3
Reseland, J.E.4
-
39
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
F. Elefteriou, J.D. Ahn, S. Takeda, M. Starbuck, X. Yang, and X. Liu Leptin regulation of bone resorption by the sympathetic nervous system and CART Nature 434 2005 514 520
-
(2005)
Nature
, vol.434
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
-
40
-
-
1542316258
-
Leptin deficiency produces contrasting phenotypes in bones of the limb and spine
-
M.W. Hamrick, C. Pennington, D. Newton, D. Xie, and C. Isales Leptin deficiency produces contrasting phenotypes in bones of the limb and spine Bone 34 2004 376 383
-
(2004)
Bone
, vol.34
, pp. 376-383
-
-
Hamrick, M.W.1
Pennington, C.2
Newton, D.3
Xie, D.4
Isales, C.5
-
41
-
-
0030947025
-
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
-
G. Luo, P. Ducy, M.D. McKee, G.J. Pinero, E. Loyer, and R.R. Behringer Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein Nature 386 1997 78 81
-
(1997)
Nature
, vol.386
, pp. 78-81
-
-
Luo, G.1
Ducy, P.2
McKee, M.D.3
Pinero, G.J.4
Loyer, E.5
Behringer, R.R.6
-
42
-
-
0026048415
-
Direct and sex-specific enhancement of bone formation and calcification by sex steroids in fetal mice long bone in vitro biochemical and morphometric study
-
Z. Schwartz, W.A. Soskolne, T. Neubauer, M. Goldstein, S. Adi, and A. Ornoy Direct and sex-specific enhancement of bone formation and calcification by sex steroids in fetal mice long bone in vitro biochemical and morphometric study Endocrinology 129 1991 1167 1174
-
(1991)
Endocrinology
, vol.129
, pp. 1167-1174
-
-
Schwartz, Z.1
Soskolne, W.A.2
Neubauer, T.3
Goldstein, M.4
Adi, S.5
Ornoy, A.6
-
43
-
-
0027980027
-
Hormonal regulation of longitudinal bone growth
-
A. Nilsson, C. Ohlsson, O.G. Isaksson, A. Lindahl, and J. Isgaard Hormonal regulation of longitudinal bone growth Eur. J. Clin. Nutr. 48 Suppl. 1 1994 S150 S158
-
(1994)
Eur. J. Clin. Nutr.
, vol.48
, Issue.1 SUPPL.
-
-
Nilsson, A.1
Ohlsson, C.2
Isaksson, O.G.3
Lindahl, A.4
Isgaard, J.5
|