Quantitative structure-activity relationship analysis of aryl alkanol piperazine derivatives with antidepressant activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2009, Pages 4367-4375

  Chen, Ke Xian ^a   Li, Zu Guang ^a   Xie, Hai Ying ^a   Gao, Jian Rong ^a   Zou, Jian Wei ^b  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Antidepressant activities; Aryl alkanol piperazine derivatives; Genetic function approximation (GFA); Genetic partial least squares (G PLS); Molecular field analysis (MFA); Quantitative structure activity relationship (QSAR)

Indexed keywords

ALKANOL PIPERAZINE DERIVATIVE; ANTIDEPRESSANT AGENT; NORADRENALIN; PIPERAZINE DERIVATIVE; SEROTONIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; DRUG STRUCTURE; INTERMETHOD COMPARISON; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTIDEPRESSIVE AGENTS; BINDING SITES; DRUG DESIGN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERAZINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SEROTONIN;

EID: 70349761363     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.05.029     Document Type: Article

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