Quantitative structure activity relationship studies of aryl heterocycle-based thrombin inhibitors

European Journal of Medicinal Chemistry

Volumn 41, Issue 11, 2006, Pages 1339-1346

  Deswal, Sumit ^a   Roy, Nilanjan ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Aryl heterocyclic; Genetic function approximation; QSAR; Thrombin inhibitors

Indexed keywords

POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PYRIDINE DERIVATIVE; TETRAZOLE DERIVATIVE; THROMBIN INHIBITOR; TRIAZOLE DERIVATIVE;

ARTICLE; DRUG INHIBITION; DRUG STRUCTURE; GENE FUNCTION; GENETIC ALGORITHM; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL SIGNIFICANCE; THERMODYNAMICS;

ANTICOAGULANTS; ENZYME INHIBITORS; PYRAZINES; PYRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 33750521975     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.07.001     Document Type: Article

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