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Volumn 98, Issue 11, 2009, Pages 4027-4038

Estimation of the extent of oral absorption in animals from oral and intravenous pharmacokinetic data in drug discovery

Author keywords

Absorption; ADME; Bioavailability; Hepatic clearance; Oral absorption; Pharamcokinetics

Indexed keywords

DRUG;

EID: 70349645327     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21705     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
    • Amidon GL, Lennernas H, Shah PV, Crison JR. 1995. A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 12:413-420.
    • (1995) Pharm Res , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernas, H.2    Shah, P.V.3    Crison, J.R.4
  • 2
    • 0030444550 scopus 로고
    • Guidance in the setting of drug particle size specifications to minimize variability in absorption
    • Johnson KC, Swindell AC. 1966. Guidance in the setting of drug particle size specifications to minimize variability in absorption. Pharm Res 13:1795-1798.
    • (1966) Pharm Res , vol.13 , pp. 1795-1798
    • Johnson, K.C.1    Swindell, A.C.2
  • 3
    • 0033999569 scopus 로고    scopus 로고
    • Development of predictive pharmacokinetic simulation models for drug discovery
    • Norris DA, Leesman GD, Sinko PJ, Grass GM. 2000. Development of predictive pharmacokinetic simulation models for drug discovery. J Control Release 65:55-62.
    • (2000) J Control Release , vol.65 , pp. 55-62
    • Norris, D.A.1    Leesman, G.D.2    Sinko, P.J.3    Grass, G.M.4
  • 4
    • 0036380244 scopus 로고    scopus 로고
    • Theoretical predictions of drug absorption in drug discovery and development
    • Stenberg P, Bergstrom CAS, Luthman K, Artursson P. 2002. Theoretical predictions of drug absorption in drug discovery and development. Clin Pharmacokin 41:877-899.
    • (2002) Clin Pharmacokin , vol.41 , pp. 877-899
    • Stenberg, P.1    Bergstrom, C.A.S.2    Luthman, K.3    Artursson, P.4
  • 6
    • 0041882163 scopus 로고    scopus 로고
    • An in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs
    • DOI 10.1016/S0378-5173(03)00343-0
    • He X, Sugawara M, Kobayashi M, Takekuma Y, Miyazaki K. 2003. An in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs. Int J Pharm 263:35-44. (Pubitemid 37087930)
    • (2003) International Journal of Pharmaceutics , vol.263 , Issue.1-2 , pp. 35-44
    • He, X.1    Sugawara, M.2    Kobayashi, M.3    Takekuma, Y.4    Miyazaki, K.5
  • 7
    • 0035800246 scopus 로고    scopus 로고
    • Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2
    • DOI 10.1016/S0378-5173(01)00698-6, PII S0378517301006986
    • Krishna G, Chen KJ, Lin CC, Nomeir AA. 2001. Permeability of lipophilic compounds in drug discovery using in vitro human absorption model, Caco-2. Int J Pharm 222:77-89. (Pubitemid 32525789)
    • (2001) International Journal of Pharmaceutics , vol.222 , Issue.1 , pp. 77-89
    • Krishna, G.1    Chen, K.-J.2    Lin, C.-C.3    Nomeir, A.A.4
  • 8
    • 0031005057 scopus 로고    scopus 로고
    • Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 model
    • DOI 10.1023/A:1012140709158
    • Taylor EW, Gibbons JA, Braeckman RA. 1997. Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 Model. Pharm Res 14:572-577. (Pubitemid 27220273)
    • (1997) Pharmaceutical Research , vol.14 , Issue.5 , pp. 572-577
    • Taylor, E.W.1    Gibbons, J.A.2    Braeckman, R.A.3
  • 9
    • 0033977587 scopus 로고    scopus 로고
    • Determination of in vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandem mass spectrometry
    • DOI 10.1002/(SICI)1096-9888(200001)35:1<71::AID-JMS915>3.0.CO;2-5
    • Wang Z, Hope CECA, Leung KH, Pang JM. 2000. Determination of in vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandom mass spectrometry. J Mass Spectrom 35:71-76. (Pubitemid 30060154)
    • (2000) Journal of Mass Spectrometry , vol.35 , Issue.1 , pp. 71-76
    • Wang, Z.1    Hop, C.E.C.A.2    Leung, K.H.3    Pang, J.4
  • 10
    • 0030986812 scopus 로고    scopus 로고
    • Analysis of drug permeation across Caco-2 monolayer: Implication for predicting in vivo drug absorption
    • DOI 10.1023/A:1012103700981
    • Yamashita S, Tanaka Y, Endoh Y, Taki Y, Sakane T, Nadai T, Sezaki H. 1997. Analysis of drug permeation across Caco-2 monolayer: Implication for predicting in vivo drug absorption. Pharm Res 14:486-491. (Pubitemid 27205009)
    • (1997) Pharmaceutical Research , vol.14 , Issue.4 , pp. 486-491
    • Yamashita, S.1    Tanaka, Y.2    Endoh, Y.3    Taki, Y.4    Sakane, T.5    Nadai, T.6    Sezaki, H.7
  • 11
    • 0034609833 scopus 로고    scopus 로고
    • Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
    • DOI 10.1021/jm000942e
    • Ertl P, Rohde B, Selzer P. 2000. Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J Med Chem 43:3714-3717. (Pubitemid 30764293)
    • (2000) Journal of Medicinal Chemistry , vol.43 , Issue.20 , pp. 3714-3717
    • Ertl, P.1    Rohde, B.2    Selzer, P.3
  • 12
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(96)00423-1, PII S0169409X96004231
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. 1997. Experimental and computational approach to estimate solubility and permeability in drug discovery and development settings. Adv Drug Delivery Rev 23:3-25. (Pubitemid 27046991)
    • (1997) Advanced Drug Delivery Reviews , vol.23 , Issue.1-3 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 13
    • 0030914681 scopus 로고    scopus 로고
    • Polar molecular surface properties predict the intestinal absorption of drugs in humans
    • DOI 10.1023/A:1012188625088
    • Palm K, Stenberg P, Luthman K, Artursson P. 1997. Polar molecular surface properties predict the intestinal absorption of drugs in humans. Pharm Res 14:568-571. (Pubitemid 27220272)
    • (1997) Pharmaceutical Research , vol.14 , Issue.5 , pp. 568-571
    • Palm, K.1    Stenberg, P.2    Luthman, K.3    Artursson, P.4
  • 14
    • 0032585545 scopus 로고    scopus 로고
    • Evaluation of dynamic polar molecular surface area as predictor of drug absorption: Comparison with other computational and experimental predictors
    • DOI 10.1021/jm980313t
    • Palm K, Luthman K, Ungell AL, Strandlund G, Beigi F, Lundahl P, Artursson P. 1998. Evaluation of dynamic polar molecular surface area as predictor of drug absorption: Comparison with other computational and experimental predictions. J Med Chem 41:5382-5392. (Pubitemid 29031322)
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.27 , pp. 5382-5392
    • Palm, K.1    Luthman, K.2    Ungell, A.-L.3    Strandlund, G.4    Beigi, F.5    Lundahl, P.6    Artursson, P.7
  • 16
    • 0037364162 scopus 로고    scopus 로고
    • ADMET in silico modeling: Toward prediction paradise?
    • van de Waterbeemd H, Gifford E. 2003. ADMET in silico modeling: Toward prediction paradise? Nat Rev Drug Discov 2:192-204.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 192-204
    • Van De Waterbeemd, H.1    Gifford, E.2
  • 17
    • 15044351293 scopus 로고    scopus 로고
    • Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neuronal network techniques
    • DOI 10.1016/j.bmcl.2005.01.081
    • Gil C, Dorronsoro I, Castro A, Martinez A. 2005. Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neural network techniques. Bioorg Med Chem Lt 5:1919-1921. (Pubitemid 40380759)
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , Issue.7 , pp. 1919-1921
    • Gil, C.1    Dorronsoro, I.2    Castro, A.3    Martinez, A.4
  • 18
    • 0033404228 scopus 로고    scopus 로고
    • Absorption potential and its variants
    • Boxenbaum H. 1999. Absorption potential and its variants. Pharm Res 16:1893.
    • (1999) Pharm Res , vol.16 , pp. 1893
    • Boxenbaum, H.1
  • 19
  • 21
    • 0345306618 scopus 로고    scopus 로고
    • Prediction of Human Pharmacokinetics from Animal Data and Molecular Structural Parameters Using Multivariate Regression Analysis: Oral Clearance
    • DOI 10.1002/jps.10510
    • Wajima T, Fukumura K, Yano Y, Oguma T. 2003. Prediction of human pharmacokinetics from animal dataand molecular structural parameters using multivariate regression analysis: Oral clearance. J Pharm Sci 92:2427-2440. (Pubitemid 37484769)
    • (2003) Journal of Pharmaceutical Sciences , vol.92 , Issue.12 , pp. 2427-2440
    • Wajima, T.1    Fukumura, K.2    Yano, Y.3    Oguma, T.4
  • 22
    • 0026694388 scopus 로고
    • Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers
    • Tse FL, Jaffe JM, Troendle A. 1992. Pharmacokinetics of fluvastatin after single and multiple doses in normal volunteers. J Clin Pharmacol 32:630-638.
    • (1992) J Clin Pharmacol , vol.32 , pp. 630-638
    • Tse, F.L.1    Jaffe, J.M.2    Troendle, A.3
  • 26
    • 0025265465 scopus 로고
    • Determination of hepatic blood flow in the rat using sequential infusions of indocyanine green or galactose
    • Pollack GM, Brouwer KLR, Demby KB, Jones JA. 1990. Determination of hepatic blood flow in the rat using sequential infusions of indocyanine green or galactose. Drug Metab Dispos 18:197-202.
    • (1990) Drug Metab Dispos , vol.18 , pp. 197-202
    • Pollack, G.M.1    Brouwer, K.L.R.2    Demby, K.B.3    Jones, J.A.4
  • 27
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • DOI 10.1023/A:1018943613122
    • Davies B, Morris T. 1993. Physiological parameters of laboratory animals and humans. Pharm Res 10:1093-1095. (Pubitemid 23211439)
    • (1993) Pharmaceutical Research , vol.10 , Issue.7 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 28
    • 0034034259 scopus 로고    scopus 로고
    • High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery
    • DOI 10.1146/annurev.pharmtox.40.1.133
    • White RE. 2000. High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery. Ann Rev Pharmacol Toxicol 40:133-157. (Pubitemid 30340676)
    • (2000) Annual Review of Pharmacology and Toxicology , vol.40 , pp. 133-157
    • White, R.E.1
  • 29
    • 33745764018 scopus 로고    scopus 로고
    • Utility of mass spectrometry for in-vitro ADME assays
    • Chu I, Nomeir AA. 2006. Utility of mass spectrometry for in-vitro ADME assays. Curr Drug Metab 7:467-477.
    • (2006) Curr Drug Metab , vol.7 , pp. 467-477
    • Chu, I.1    Nomeir, A.A.2
  • 30
    • 48549096838 scopus 로고    scopus 로고
    • Species differences in in vitro and in vivo small intestinal metabolism of CYP3A substrates
    • Komura H, Iwaki M. 2008 Species differences in in vitro and in vivo small intestinal metabolism of CYP3A substrates. J Pharm Sci 9:1775-1800.
    • (2008) J Pharm Sci , vol.9 , pp. 1775-1800
    • Komura, H.1    Iwaki, M.2
  • 31
    • 33646818650 scopus 로고    scopus 로고
    • Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans
    • DOI 10.1080/00498250600571749, PII U57671171353
    • Sakuda S, Akabane T, Teramura T. 2006. Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans. Xenobiotica 36:331-340. (Pubitemid 43754758)
    • (2006) Xenobiotica , vol.36 , Issue.4 , pp. 331-340
    • Sakuda, S.1    Akabane, T.2    Teramura, T.3
  • 33
    • 34547209778 scopus 로고    scopus 로고
    • Asymmetric intestinal first-pass metabolism causes minimal oral bioavailability of midazolam in cynomolgus monkey
    • DOI 10.1124/dmd.106.013037
    • Nishimura T, Amano N, Kubo Y, Ono M, Kato Y, Fujita H, Kimura Y, Tsuji A. 2007. Asymmetric intestinal first-pass metabolism causes minimal oral bioavailability of midazolam in cynomolgus monkey. Drug Metab Dispos 35:1275-1284. (Pubitemid 47121767)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.8 , pp. 1275-1284
    • Nishimura, T.1    Amano, N.2    Kubo, Y.3    Ono, M.4    Kato, Y.5    Fujita, H.6    Kimura, Y.7    Tsuji, A.8
  • 34
    • 0017888789 scopus 로고
    • Absorption of the beta-adrenergic-blocking agent, nadolol, by mice, rats, hamsters, rabbits, dogs, monkeys, and man: An unusual species difference
    • Dreyfuss J, Shaw JM, Ross JJ, Jr. 1978. Absorption of the beta-adrenergic-blocking agent, nadolol, by mice, rats, hamsters, rabbits, dogs, monkeys, and man: An unusual species difference. Xenobiotica 8:503-508.
    • (1978) Xenobiotica , vol.8 , pp. 503-508
    • Dreyfuss, J.1    Shaw, J.M.2    Ross Jr., J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.