Enhanced HtrA2/Omi expression in oxidative injury to retinal pigment epithelial cells and murine models of neurodegeneration

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 10, 2009, Pages 4957-4966

  Ding, Xiaoyan ^a,b   Patel, Mrinali ^a,c   Shen, Defen ^a   Herzlich, Alexandra A ^a   Cao, Xiaoguang ^a,d   Villasmil, Rafael ^a   Klupsch, Kristina ^e   Tuo, Jingsheng ^a   Downward, Julian ^e   Chan, Chi Chao ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERINE PROTEINASE OMI; CASP3 PROTEIN, MOUSE; CCL2 PROTEIN, MOUSE; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; ENZYME INHIBITOR; MITOCHONDRIAL PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PYRIMIDINONE DERIVATIVE; SERINE PROTEINASE; THIOKETONE; UCF 101; X LINKED INHIBITOR OF APOPTOSIS; XIAP PROTEIN, HUMAN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNT; CELL DAMAGE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PHOTORECEPTOR; PIGMENT CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; CELL SURVIVAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; PIGMENT EPITHELIUM; PROTEIN TRANSPORT; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL LINE; CELL SURVIVAL; CHEMOKINE CCL2; CYTOSOL; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROGEN PEROXIDE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PROTEIN TRANSPORT; PYRIMIDINONES; RECEPTORS, CHEMOKINE; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SERINE ENDOPEPTIDASES; THIONES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 70349581640     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3381     Document Type: Article

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