α4β1-integrin activation is necessary for high-efficiency T-cell subset interactions with VCAM-1 under flow

Microcirculation

Volumn 7, Issue 3, 2000, Pages 201-214

  Lim, Yaw Chyn ^a   Wakelin, Matthew W ^a   Henault, Lori ^a   Goetz, Douglas J ^b   Yednock, Ted ^c   Cabañas, Carlos ^d   Sánchez Madrid, Francisco ^e   Lichtman, Andrew H ^a   Luscinskas, Francis W ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Ohio University   (United States)

^c Athena Neurosciences Inc   (United States)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

Immune reaction; Integrins; T lymphocytes

Indexed keywords

CD45 ANTIGEN; HOMING RECEPTOR; INTEGRIN; LYMPHOKINE; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ARTICLE; BIOSYNTHESIS; BLOOD RHEOLOGY; CELL ADHESION; CYTOLOGY; FLOW CYTOMETRY; HUMAN; IMMUNOLOGICAL MEMORY; LYMPHOCYTE ACTIVATION; METABOLISM; NEUTROPHIL CHEMOTAXIS; PHYSIOLOGY; TH1 CELL; TH2 CELL;

ANTIGENS, CD45; CELL ADHESION; CHEMOTAXIS, LEUKOCYTE; FLOW CYTOMETRY; HEMORHEOLOGY; HUMANS; IMMUNOLOGIC MEMORY; INTEGRIN ALPHA4BETA1; INTEGRINS; LYMPHOCYTE ACTIVATION; LYMPHOKINES; RECEPTORS, LYMPHOCYTE HOMING; TH1 CELLS; TH2 CELLS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0034204188     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1549-8719.2000.tb00121.x     Document Type: Article

References (51)

1. Alon R, Fuhlbrigge RC, Finger EB, Springe TA. (1996). Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selecting and VCAM-1 in shear flow. J Cell Biol 135:849-865.
2. Alon R, Kassuer PD, Carr MW, Finger EB, Hemler ME, Springer TA. (1995a). The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J Cell Biol 128:1243-1253.
3. Alon R, Rossiter H, Wang X, Springer TA, Kupper TS. (1995b). Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow. J Cell Biol 127:1485-1495.
4. Arroyo AC, Garcia-Vicuna R, Marazuela M, Yednock TA, Gonzalez-Amaro R, Sanchez-Madrid F. (1995). Expression and functional significance of an activation-dependent epitope of the β1 integrins in chronic inflammatory diseases. Eur J Immunol 25:1720-1728.
5. Assenmacher M, Schmitz J, Radbruch A. (1994). Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of inlerleukin-10 in interferon-gamma and in interleukin-4 expressing cells. Eur J Immunol 24:1097-1101.
6. Austrup F, Vestweber D, Borges E, Lohning M, Brauer R, Herz U, Renz H, Hallmann R, Scheffold A, Radbruch A, Hamann A. (1997). P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385:81-83.
7. Baraniuk JN. (1997). Pathogenesis of allergic rhinitis. J Allergy Clin Immunol 99:S763-S772.
8. Berlin C, Bargatze RF, Campbell JJ, von Andrian UH, Szabo MC, Hasslen SR, Nelson RD, Berg EL, Erlandsen SL, Butcher EC. (1995). Alpha-4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80:413-422.
9. Bonecchi R, Bianchi G, Bordinon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A, Sinigaglia F. (1998). Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 187:129-134.
10. Borges E, Tietz W, Steegmaier M, Moll T, Hallmann R, Hamann A, Vestweber D. (1997). P-selectin glycoprotein ligand-1 (PSGL-1 ) on T helper 1 but not on T helper 2 cells binds a P-selectin and supports migration into inflamed skin. J Exp Med 185:573-578.
11. + T cells that exhibit a transendothelial migratory capacity. J Immunol 154:3062-3077.
12. Briskin MJ, McEvoy LM, Butcher EC. (1993). MAd-Cam-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. Nature 363:461-464.
13. Brusselle GG, Kips JC, Joos G, Bluethmann H, Pauwels RA. (1995). Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am J Respir Cell Mol Biol 12:254-259.
14. Cabanas C, Hogg N. (1993). Ligand intercellular adhesion molecule-1 has a necessary role in activation of integrin lymphocyte function-associated molecule-1. Proc Natl Acad Sci USA 90:5838-5842.
15. Campanero MR, Arroyo AG, Pulido R, Ursa A, de Matias MS, Sanchez-Mateos P, Kassner PD, Chan BMC, Hemler ME, Corbi AL, de Lándazuri MO, Sanchez-Madrid F. (1992). Functional role of alpha 2/beta 1 and alpha 4/beta 1 integrins in leukocyte intercellular adhesion through the common beta-1 subunit. Eur J Immunol 22:3111-3119.
16. Del Prete GF, De Carli M, D'Elios MM, Maestrelli P, Ricci M, Fabbri L, Romagnani S. (1993). Allergen exposure induces the activation of allergen-specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders. Eur J Immunol 23:1445-1449.
17. Diamond MS, Springer TA. (1993). A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol 120:545-556.
18. Du XP, Plow EF, Frelinger AL, O'Toole TE, Loftus JC, Ginsberg MH. (1991). Ligands "activate" integrin alpha IIb beta 3 (platelet GP IIb-IIIa). Cell 65: 409-416.
19. Gavett SH, Chen X, Finkelman F, Wills-Karp M. (1994). Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 10:587-593.
20. Goetz DJ, Ding H, Atkinson WJ, Vachino G, Camphausen RT, Cumming D, Luscinskas FW. (1996). A colon carcinoma cell line exhibits adhesive interactions with P-selectin under flow via a PSGL-1 independent mechanism. Am J Pathol 149:1661-1673.
21. Lalor PF, Clements JM, Pigott R, Humphries MJ, Spragg JH, Nash GB. (1997). Association between receptor density, cellular activation, and transformation of adhesive behavior of flowing lymphocytes binding to VGAM-1. Eur J Immunol 27:1422-1426.
22. Lee BJ, Naclerio RM, Bochner BS, Taylor BM, Lim MC, Baroody FM. (1994). Nasal challenge with allergen upregulates the local expression of vascular endothelial adhesion molecules. J Allergy Clin Immunol 94:1006-1016.
23. Lenschow DJ, Walunas TL, Bluestone JA. (1996). CD28/B7 system of T cell costimulation. Annu Rev Immunol 14:233-258.
24. + T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today 16:34-38.
25. Lichtman AH, Abbas AK. (1997a). T-cell subsets: recruiting the right kind of help. Curr Biol 7:R242-R244.
26. - (naive) T cells roll efficiently on E-and P-selectin and vascular cell adhesion molecule-1 under flow. J Immunol 158:3640-3650.
27. Lim Y-C, Ding H, Kansas GS, Snapp K, Luscinskas FW. (1998). Contributions of PSGL-1-mediated secondary capture to human monocyte adhesion to P-selectin, E-selectin, and TNF-α-activated endothelium under flow in vitro. J Immunol 161:2501-2508.
28. Lim Y-C, Henault L, Wagers AJ, Kansas GS, Luscinskas FW, Lichtman AH. (1999). Expression of functional selectin ligands on Th cells is differentially regulated by IL-12 and IL-4. J Immunol 162:3193-3201.
29. Luque A, Gomez M, Puzon W, Takada Y, Sanchez-Madrid F, Cabanas C. (1996). Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common β1 chain. J Biol Chem 271:11067-11075.
30. Luscinskas FW, Ding H, Lichtman AH. (1995). P-selectin and VGAM-1 mediate rolling and arrest of CD4+ T-lymphocytes on TNF-a-activated vascular endothelium under flow. J Exp Med 181:1179-1186.
31. + T-cell subsets in autoimmunity. Curr Opin Immunol 9: 872-883.
32. Openshaw P, Murphy EE, Hosken NA, Maino V, Davis K, Murphy KM, O'Garra A. (1995). Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J Exp Med 182:1357-1367.
33. Paul WE, Seder RA. (1994). Lymphocyte responses and cytokines. Cell 76:241-251.
34. Picker LJ. (1994). Control of lymphocyte homing. Curr Opin Immunol 6:394-406.
35. Picker LJ, Singh MK, Zdraveski Z, Treer JR, Waldrop SL, Bergstresser PR, Maino VC. (1995). Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 86:1408-1419.
36. 2 integrin "activation" epitopes during T cell responses in secondary lymphoid tissue. Eur J Immunol 23:2751-2757.
37. Pietschmann P, Cush JJ, Lipsky PE, Oppenheimer-Marks N. (1992). Identification of subsets of human T cells capable of enhancing transendothelial migration. J Immunol 149:1170-1178.
38. Puzon-McLaughlin W, Yednock T, Takada Y. (1996). Regulation of conformation and ligand binding function of integrin α5β1 by the β1 cytoplasmic domain. J Biol Chem 271:16580-16585.
39. Rice GE, Munro JM, Corless C, Bevilacqua MP. (1991). Vascular and nonvascular expression of INCAM-110. A target for mononuclear leucocyte adhesion in normal and inflamed human tissues. Am J Pathol 138:385-393.
40. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley A, Corrigan G, Durham S, Kay B. (1992). Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 326:298-305.
41. Romagnani S. (1994). Lymphokine production by human T cells in disease states. Rev Immunol 12:227-257.
42. Rott ES, Briskin MJ, Andrew DP, Berg EE, Butcher EC. (1996). A fundamental subdivision of circulating lymphocytes defined by adhesion to mucosal addressin cell adhesion molecule-1. Comparison with vascular cell adhesion molecule-1 and correlation with beta 7 integrins and memory differentiation. J Immunol 156:3727-3736.
43. Schweighoffer T, Tanaka Y, Tidswell M, Erle DJ, Horgan KJ, Ginther Luce GE, Lazarovits AI, Buck D, Shaw S. ( 1993). Selective expression of integrin α4β7 on a subset of human CD4+ memory T cells with hallmarks of gut-trophism. J Immunol 151:717-729.
44. + T cells. Annu Rev Immunol 12:635-673.
45. Shimizu Y, van Seventer GA, Ennis E, Newman W, Horgan KJ, Shaw S. (1992). Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion. J Exp Med 175:577-682.
46. 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domaines of INCAM-110/VCAM-1. Cell Reg 2:347-355.
47. Vachino G, Chang X-J, Veldman GM, Kumar R, Fouser LA, Berndt MC, Cumming DA. (1995). P-selectin glycoprotein ligand-1 is the major counter-receptor for P-selectin on stimulated T cells and is widely distributed in non-functional form on many lymphocytic cells. J Biol Chem 270:21966-21974.
48. von Kooyk Y, van de Wiel-van Kemenade P, Weder P, Kuijpers TW, Figdor CG. (1989). Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature 342: 811-813.
49. Ward SC, Bacon K, Westwick J. (1998). Chemokines and T lymphocytes: more than an attraction. Immunity 9:1-11.
50. + T cells. J Exp Med 189:1765-1775.
51. 1 integrin-dependent cell adhesion is regulated by a low affinity receptor pool that is conformationally responsive to ligand. J Biol Chem 270: 28740-28750.