Surface binding inhibitors of the SCF-KIT protein-protein interaction

ChemBioChem

Volumn 10, Issue 12, 2009, Pages 1955-1958

  Marguiles, David ^a   Opatowsky, Yarden ^b   Fletcher, Steven ^a   Saraogi, Ishu ^a   Tsou, Lun K ^a   Saha, Sourav ^a   Lax, Irit ^b   Schelessinger, Joseph ^b   Hamilton, Andrew D ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug design; Protein protein interactions; SCF KIT; Supramolecular chemistry; Synthetic inhibitors

Indexed keywords

PORPHYRIN DERIVATIVE; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TETRAKIS(4 CARBOXYPHENYL)PORPHINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; ELECTRIC POTENTIAL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-KIT; SIGNAL TRANSDUCTION; STEM CELL FACTOR; SURFACE PROPERTIES;

EID: 70349559761     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900079     Document Type: Article

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