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Volumn 30, Issue 10, 2009, Pages 488-493

Esterases and autoimmunity: the sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD22 ANTIGEN; ESTERASE; LECTIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; RAG1 PROTEIN; RAG2 PROTEIN; SIALIC ACID ACETYLESTERASE; SIALIC ACID DERIVATIVE; SIGLEC PROTEIN; UNCLASSIFIED DRUG;

EID: 70349559578     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2009.07.006     Document Type: Review
Times cited : (42)

References (45)
  • 1
    • 37549040575 scopus 로고    scopus 로고
    • The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members
    • Verdine G.L., and Walensky L.D. The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members. Clin Cancer Res 13 24 (2007) 7264-7270
    • (2007) Clin Cancer Res , vol.13 , Issue.24 , pp. 7264-7270
    • Verdine, G.L.1    Walensky, L.D.2
  • 2
    • 60549105605 scopus 로고    scopus 로고
    • B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase
    • Cariappa A., et al. B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase. J Exp Med 206 1 (2009) 125-138
    • (2009) J Exp Med , vol.206 , Issue.1 , pp. 125-138
    • Cariappa, A.1
  • 3
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam K.P., et al. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90 6 (1997) 1073-1083
    • (1997) Cell , vol.90 , Issue.6 , pp. 1073-1083
    • Lam, K.P.1
  • 4
    • 2942582913 scopus 로고    scopus 로고
    • Survival of resting mature B lymphocytes depends on BCR signaling via the Ig alpha/beta heterodimer
    • Kraus M., et al. Survival of resting mature B lymphocytes depends on BCR signaling via the Ig alpha/beta heterodimer. Cell 117 6 (2004) 787-800
    • (2004) Cell , vol.117 , Issue.6 , pp. 787-800
    • Kraus, M.1
  • 5
    • 20944435721 scopus 로고    scopus 로고
    • Basal immunoglobulin signaling actively maintains developmental stage in immature B cells
    • Tze L.E., et al. Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. PLoS Biol 3 3 (2005) e82
    • (2005) PLoS Biol , vol.3 , Issue.3
    • Tze, L.E.1
  • 6
    • 12344273628 scopus 로고    scopus 로고
    • Marginal zone B cells
    • Pillai S., et al. Marginal zone B cells. Annu Rev Immunol 23 (2005) 161-196
    • (2005) Annu Rev Immunol , vol.23 , pp. 161-196
    • Pillai, S.1
  • 7
    • 0027499537 scopus 로고
    • Receptor editing: an approach by autoreactive B cells to escape tolerance
    • Gay D., et al. Receptor editing: an approach by autoreactive B cells to escape tolerance. J Exp Med 177 4 (1993) 999-1008
    • (1993) J Exp Med , vol.177 , Issue.4 , pp. 999-1008
    • Gay, D.1
  • 8
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone-marrow B cells
    • Tiegs S.L., et al. Receptor editing in self-reactive bone-marrow B cells. J Exp Med 177 (1993) 1009-1020
    • (1993) J Exp Med , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1
  • 9
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
    • Nemazee D.A., and Burki K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337 6207 (1989) 562-566
    • (1989) Nature , vol.337 , Issue.6207 , pp. 562-566
    • Nemazee, D.A.1    Burki, K.2
  • 10
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley S.B., et al. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353 6346 (1991) 765-769
    • (1991) Nature , vol.353 , Issue.6346 , pp. 765-769
    • Hartley, S.B.1
  • 11
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death
    • Hartley S.B., et al. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 72 3 (1993) 325-335
    • (1993) Cell , vol.72 , Issue.3 , pp. 325-335
    • Hartley, S.B.1
  • 12
    • 0023729241 scopus 로고
    • Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
    • Goodnow C.C., et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334 6184 (1988) 676-682
    • (1988) Nature , vol.334 , Issue.6184 , pp. 676-682
    • Goodnow, C.C.1
  • 13
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster J.G., et al. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371 6496 (1994) 389-395
    • (1994) Nature , vol.371 , Issue.6496 , pp. 389-395
    • Cyster, J.G.1
  • 14
    • 1842581849 scopus 로고    scopus 로고
    • Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells
    • Ekland E.H., et al. Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells. J Immunol 172 8 (2004) 4700-4708
    • (2004) J Immunol , vol.172 , Issue.8 , pp. 4700-4708
    • Ekland, E.H.1
  • 15
    • 0031424315 scopus 로고    scopus 로고
    • Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification
    • Pelanda R., et al. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity 7 6 (1997) 765-775
    • (1997) Immunity , vol.7 , Issue.6 , pp. 765-775
    • Pelanda, R.1
  • 16
    • 2942652985 scopus 로고    scopus 로고
    • Receptor editing is the main mechanism of B cell tolerance toward membrane antigens
    • Halverson R., et al. Receptor editing is the main mechanism of B cell tolerance toward membrane antigens. Nat Immunol 5 6 (2004) 645-650
    • (2004) Nat Immunol , vol.5 , Issue.6 , pp. 645-650
    • Halverson, R.1
  • 17
    • 23244447690 scopus 로고    scopus 로고
    • In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance
    • Hippen K.L., et al. In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. J Immunol 175 2 (2005) 909-916
    • (2005) J Immunol , vol.175 , Issue.2 , pp. 909-916
    • Hippen, K.L.1
  • 18
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • Wardemann H., et al. Predominant autoantibody production by early human B cell precursors. Science 301 5638 (2003) 1374-1377
    • (2003) Science , vol.301 , Issue.5638 , pp. 1374-1377
    • Wardemann, H.1
  • 19
    • 59649105484 scopus 로고    scopus 로고
    • RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes
    • Panigrahi A.K., et al. RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes. J Exp Med 205 13 (2008) 2985-2994
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 2985-2994
    • Panigrahi, A.K.1
  • 20
    • 33745161013 scopus 로고    scopus 로고
    • Regulation of B cell tolerance by the lupus susceptibility gene Ly108
    • Kumar K.R., et al. Regulation of B cell tolerance by the lupus susceptibility gene Ly108. Science 312 5780 (2006) 1665-1669
    • (2006) Science , vol.312 , Issue.5780 , pp. 1665-1669
    • Kumar, K.R.1
  • 21
    • 33947602811 scopus 로고    scopus 로고
    • Siglecs and their roles in the immune system
    • Crocker P.R., et al. Siglecs and their roles in the immune system. Nat Rev Immunol 7 4 (2007) 255-266
    • (2007) Nat Rev Immunol , vol.7 , Issue.4 , pp. 255-266
    • Crocker, P.R.1
  • 22
    • 0027511875 scopus 로고
    • Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition
    • Powell L.D., et al. Natural ligands of the B cell adhesion molecule CD22 beta carry N-linked oligosaccharides with alpha-2,6-linked sialic acids that are required for recognition. J Biol Chem 268 10 (1993) 7019-7027
    • (1993) J Biol Chem , vol.268 , Issue.10 , pp. 7019-7027
    • Powell, L.D.1
  • 23
    • 0030467610 scopus 로고    scopus 로고
    • CD22 regulates thymus-independent responses and the lifespan of B cells
    • Otipoby K.L., et al. CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 384 6610 (1996) 634-637
    • (1996) Nature , vol.384 , Issue.6610 , pp. 634-637
    • Otipoby, K.L.1
  • 24
    • 0029909049 scopus 로고    scopus 로고
    • Hyperresponsive B cells in CD22-deficient mice
    • O'Keefe T.L., et al. Hyperresponsive B cells in CD22-deficient mice. Science 274 5288 (1996) 798-801
    • (1996) Science , vol.274 , Issue.5288 , pp. 798-801
    • O'Keefe, T.L.1
  • 25
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice
    • Sato S., et al. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5 6 (1996) 551-562
    • (1996) Immunity , vol.5 , Issue.6 , pp. 551-562
    • Sato, S.1
  • 26
    • 0031080328 scopus 로고    scopus 로고
    • CD22 is a negative regulator of B-cell receptor signalling
    • Nitschke L., et al. CD22 is a negative regulator of B-cell receptor signalling. Curr Biol 7 2 (1997) 133-143
    • (1997) Curr Biol , vol.7 , Issue.2 , pp. 133-143
    • Nitschke, L.1
  • 27
    • 0027175115 scopus 로고
    • Association of CD22 with the B cell antigen receptor
    • Peaker C.J., and Neuberger M.S. Association of CD22 with the B cell antigen receptor. Eur J Immunol 23 6 (1993) 1358-1363
    • (1993) Eur J Immunol , vol.23 , Issue.6 , pp. 1358-1363
    • Peaker, C.J.1    Neuberger, M.S.2
  • 28
    • 38849203194 scopus 로고    scopus 로고
    • CD22: an inhibitory enigma
    • Walker J.A., and Smith K.G. CD22: an inhibitory enigma. Immunology 123 3 (2008) 314-325
    • (2008) Immunology , vol.123 , Issue.3 , pp. 314-325
    • Walker, J.A.1    Smith, K.G.2
  • 29
    • 31344445556 scopus 로고    scopus 로고
    • Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling
    • Collins B.E., et al. Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling. Nat Immunol 7 2 (2006) 199-206
    • (2006) Nat Immunol , vol.7 , Issue.2 , pp. 199-206
    • Collins, B.E.1
  • 30
    • 0029845089 scopus 로고    scopus 로고
    • Molecular cloning of the cDNA encoding a murine sialic acid-specific 9-O-acetylesterase and RNA expression in cells of hematopoietic and non-hematopoietic origin
    • Stoddart A., et al. Molecular cloning of the cDNA encoding a murine sialic acid-specific 9-O-acetylesterase and RNA expression in cells of hematopoietic and non-hematopoietic origin. Nucleic Acids Res 24 20 (1996) 4003-4008
    • (1996) Nucleic Acids Res , vol.24 , Issue.20 , pp. 4003-4008
    • Stoddart, A.1
  • 31
    • 0033520481 scopus 로고    scopus 로고
    • Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus
    • Takematsu H., et al. Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus. J Biol Chem 274 36 (1999) 25623-25631
    • (1999) J Biol Chem , vol.274 , Issue.36 , pp. 25623-25631
    • Takematsu, H.1
  • 32
    • 0028276413 scopus 로고
    • Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids
    • Sjoberg E.R., et al. Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids. J Cell Biol 126 2 (1994) 549-562
    • (1994) J Cell Biol , vol.126 , Issue.2 , pp. 549-562
    • Sjoberg, E.R.1
  • 33
    • 0042232205 scopus 로고    scopus 로고
    • Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein
    • Blixt O., et al. Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein. J Biol Chem 278 33 (2003) 31007-31019
    • (2003) J Biol Chem , vol.278 , Issue.33 , pp. 31007-31019
    • Blixt, O.1
  • 34
    • 34147219234 scopus 로고    scopus 로고
    • Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation
    • Naito Y., et al. Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation. Mol Cell Biol 27 8 (2007) 3008-3022
    • (2007) Mol Cell Biol , vol.27 , Issue.8 , pp. 3008-3022
    • Naito, Y.1
  • 35
    • 0034995180 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21
    • Cariappa A., et al. The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21. Immunity 14 5 (2001) 603-615
    • (2001) Immunity , vol.14 , Issue.5 , pp. 603-615
    • Cariappa, A.1
  • 36
    • 26644456680 scopus 로고    scopus 로고
    • Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes
    • Cariappa A., et al. Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity 23 4 (2005) 397-407
    • (2005) Immunity , vol.23 , Issue.4 , pp. 397-407
    • Cariappa, A.1
  • 37
    • 33645211369 scopus 로고    scopus 로고
    • Regulation of B cell development and B cell signalling by CD22 and its ligands alpha2,6-linked sialic acids
    • Ghosh S., et al. Regulation of B cell development and B cell signalling by CD22 and its ligands alpha2,6-linked sialic acids. Int Immunol 18 (2006) 603-611
    • (2006) Int Immunol , vol.18 , pp. 603-611
    • Ghosh, S.1
  • 38
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe T.L., et al. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 189 8 (1999) 1307-1313
    • (1999) J Exp Med , vol.189 , Issue.8 , pp. 1307-1313
    • O'Keefe, T.L.1
  • 39
    • 0028784215 scopus 로고
    • Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
    • Hibbs M.L., et al. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 83 2 (1995) 301-311
    • (1995) Cell , vol.83 , Issue.2 , pp. 301-311
    • Hibbs, M.L.1
  • 40
    • 34447624878 scopus 로고    scopus 로고
    • B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
    • Pao L.I., et al. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity 27 1 (2007) 35-48
    • (2007) Immunity , vol.27 , Issue.1 , pp. 35-48
    • Pao, L.I.1
  • 41
    • 34250753787 scopus 로고    scopus 로고
    • Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population
    • Hoffmann A., et al. Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population. Nat Immunol 8 7 (2007) 695-704
    • (2007) Nat Immunol , vol.8 , Issue.7 , pp. 695-704
    • Hoffmann, A.1
  • 42
    • 63149171602 scopus 로고    scopus 로고
    • CD24 and Siglec-10 selectively repress tissue damage-induced immune responses
    • Chen G.Y., et al. CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. Science 323 5922 (2009) 1722-1725
    • (2009) Science , vol.323 , Issue.5922 , pp. 1722-1725
    • Chen, G.Y.1
  • 43
    • 66949130737 scopus 로고    scopus 로고
    • Developmental acquisition of the Lyn-CD22-SHP-1inhibitory pathway promotes B cell tolerance
    • Gross A.J., et al. Developmental acquisition of the Lyn-CD22-SHP-1inhibitory pathway promotes B cell tolerance. J Immunol 182 (2009) 5382-5392
    • (2009) J Immunol , vol.182 , pp. 5382-5392
    • Gross, A.J.1
  • 44
    • 0032055828 scopus 로고    scopus 로고
    • Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
    • Cornall R.J., et al. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity 8 (1998) 497-508
    • (1998) Immunity , vol.8 , pp. 497-508
    • Cornall, R.J.1
  • 45
    • 0036008486 scopus 로고    scopus 로고
    • Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity?
    • Lanoue A., et al. Interaction of CD22 with alpha2,6-linked sialoglycoconjugates: innate recognition of self to dampen B cell autoreactivity?. Eur J Immunol 32 (2002) 348-355
    • (2002) Eur J Immunol , vol.32 , pp. 348-355
    • Lanoue, A.1


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