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0000604229
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No special precaution is required due to the low toxicity of manganese and manganese salts obtained after the aqueous work-up of organomanganese reactions
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No special precaution is required due to the low toxicity of manganese and manganese salts obtained after the aqueous work-up of organomanganese reactions; see: G. Cahiez, Anales de Química, 1995, 91, 561-578.
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41
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70349419174
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Aldrich catalogue (2009-2010): powder manganese (325 mesh): 250 g = 44 €
-
Aldrich catalogue (2009-2010): powder manganese (325 mesh): 250 g = 44 €
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42
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0003998388
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CRC Press, Boca Raton, FL
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56349147351
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For some recent synthetic applications of manganese in organic synthesis
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For some recent synthetic applications of manganese in organic synthesis, see: J. M. Concellón, H. Rodríguez-Solla, V. del Amo, Chem. Eur. J. 2008, 14, 10184-10191.
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38549136003
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a) J. M. Concellón, H. Rodríguez-Solla, P. Díaz, Org. Biomol. Chem. 2008, 6, 451-453;
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52
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70349431816
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The enolate was generated by treatment of the corresponding 2-chloro amide with LDA at -78°C
-
The enolate was generated by treatment of the corresponding 2-chloro amide with LDA at -78°C.
-
-
-
-
53
-
-
0033609788
-
-
Active manganese was readily prepared by using the method described by Cahiez
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Active manganese was readily prepared by using the method described by Cahiez: G. Cahiez, A. Martin, T. Delacroix, Tetrahedron Lett. 1999, 40, 6407-6410.
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0002884392
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R. Martín, P. Romea, C. Tey, F. Urpí, J. Vilarrasa, Synlett 1997, 1414-1416.
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55
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0035898426
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J. M. Concellón, J. A. Pérez-Andrés, H. Rodríguez-Solla, Chem. Eur. J. 2001, 7, 3062-3068.
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56
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4644245454
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Similar deoxygenation reactions promoted by samarium diiodide have been previously reported in the literature
-
Similar deoxygenation reactions promoted by samarium diiodide have been previously reported in the literature : a) J. M. Concellón, E. Bardales, M. Huerta Tetrahedron 2004, 60, 10059-10065;
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Tetrahedron
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Concellón, J.M.1
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Huerta, M.3
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60
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70349431814
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-
The starting epoxy esters were prepared, similarly to epoxy amides, by reaction of the potassium enolate (generated by treatment of the corresponding chloro ester with potassium hexamethyldisilazide) with 1.0 equiv. of the corresponding aldehyde at -78°C for 2 h. After this time, the reaction mixture was allowed to warm up to room temperature.
-
The starting epoxy esters were prepared, similarly to epoxy amides, by reaction of the potassium enolate (generated by treatment of the corresponding chloro ester with potassium hexamethyldisilazide) with 1.0 equiv. of the corresponding aldehyde at -78°C for 2 h. After this time, the reaction mixture was allowed to warm up to room temperature.
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15744387149
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62
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0002526211
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Compound 12a displayed analytical data in accordance with the published values
-
Compound 12a displayed analytical data in accordance with the published values: a) V. Schurig, K. Hintzer, U. Leyrer, C. Mark, P. Pitchen, H. B. Kagan, J. Organomet. Chem. 1989, 370, 81-96;
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63
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0037065320
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b) T. Němoto, H. Kakei, V. Gnanadesikan, S. Tosaki, T. Ohshima, M. Shibasaki, J. Am. Chem. Soc. 2002, 124, 14544-14545.
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Němoto, T.1
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Shibasaki, M.6
-
64
-
-
70349433211
-
-
Chiral HPLC analysis for 12a and 12b show the same
-
R 9.42, and 12.22 min.
-
R 9.42, and 12.22 Min
-
-
|