-
1
-
-
32044466239
-
Does measurement of oxidative damage to DNA have clinical significance?
-
M. S. Cooke, R. Olinski and M. D. Evans, Does measurement of oxidative damage to DNA have clinical significance? Clin. Chim. Acta 365, 30-49 (2006).
-
(2006)
Clin. Chim. Acta
, vol.365
, pp. 30-49
-
-
Cooke, M.S.1
Olinski, R.2
Evans, M.D.3
-
2
-
-
2942572700
-
Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?
-
B. Halliwell and M. Whiteman, Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br. J. Pharmacol. 142, 231-255 (2004).
-
(2004)
Br. J. Pharmacol
, vol.142
, pp. 231-255
-
-
Halliwell, B.1
Whiteman, M.2
-
3
-
-
0029932905
-
evidence of persistent oxidative stress in cancer
-
Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma
-
K. Okamoto, S. Toyokuni, W. J. Kim, O. Ogawa, Y. Kakehi, S. Arao, H. Hiai and O. Yoshida, Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer. Int. J. Cancer 65, 437-441 (1996).
-
(1996)
Int. J. Cancer
, vol.65
, pp. 437-441
-
-
Okamoto, K.1
Toyokuni, S.2
Kim, W.J.3
Ogawa, O.4
Kakehi, Y.5
Arao, S.6
Hiai, H.7
Yoshida, O.8
-
4
-
-
0037115963
-
Oxidative nucleotide damage: Consequences and prevention
-
M. Sekiguchi and T. Tsuzuki, Oxidative nucleotide damage: consequences and prevention. Oncogene 21, 8895-8904 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 8895-8904
-
-
Sekiguchi, M.1
Tsuzuki, T.2
-
5
-
-
0023931846
-
Studies on the mutator gene, mutT of Escherichia coli. Molecular cloning of the gene, purification of the gene product, and identification of a novel nucleoside triphosphatase
-
S. K. Bhatnagar and M. J. Bessman, Studies on the mutator gene, mutT of Escherichia coli. Molecular cloning of the gene, purification of the gene product, and identification of a novel nucleoside triphosphatase. J. Biol. Chem. 263, 8953-8957 (1988).
-
(1988)
J. Biol. Chem
, vol.263
, pp. 8953-8957
-
-
Bhatnagar, S.K.1
Bessman, M.J.2
-
6
-
-
0026513966
-
MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
-
H. Maki and M. Sekiguchi, MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature 355, 273-275 (1992).
-
(1992)
Nature
, vol.355
, pp. 273-275
-
-
Maki, H.1
Sekiguchi, M.2
-
7
-
-
0035796057
-
Molecular genetics and structural biology of human MutT homolog, MTH1
-
Y. Nakabeppu, Molecular genetics and structural biology of human MutT homolog, MTH1. Mutat. Res. 477, 59-70 (2001).
-
(2001)
Mutat. Res
, vol.477
, pp. 59-70
-
-
Nakabeppu, Y.1
-
8
-
-
0029835350
-
The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes
-
M. J. Bessman, D. N. Frick and S. F. O'Handley, The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. J. Biol. Chem. 271, 25059-25062 (1996).
-
(1996)
J. Biol. Chem
, vol.271
, pp. 25059-25062
-
-
Bessman, M.J.1
Frick, D.N.2
O'Handley, S.F.3
-
9
-
-
1042275585
-
Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs
-
H. Kamiya, H. Yakushiji, L. Dugue, M. Tanimoto, S. Pochet, Y. Nakabeppu and H. Harashima, Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs. J. Mol. Biol. 336, 843-850 (2004).
-
(2004)
J. Mol. Biol
, vol.336
, pp. 843-850
-
-
Kamiya, H.1
Yakushiji, H.2
Dugue, L.3
Tanimoto, M.4
Pochet, S.5
Nakabeppu, Y.6
Harashima, H.7
-
10
-
-
0027368923
-
Cloning and expression of cDNA for a human enzymethathydrolyzes8- oxo-dGTP, a mutagenic substrate for DNA synthesis
-
K. Sakumi, M. Furuichi, T. Tsuzuki, T. Kakuma, S. Kawabata, H. Maki and M. Sekiguchi, Cloning and expression of cDNA for a human enzymethathydrolyzes8- oxo-dGTP, a mutagenic substrate for DNA synthesis. J. Biol. Chem. 268, 23524-23530 (1993).
-
(1993)
J. Biol. Chem
, vol.268
, pp. 23524-23530
-
-
Sakumi, K.1
Furuichi, M.2
Tsuzuki, T.3
Kakuma, T.4
Kawabata, S.5
Maki, H.6
Sekiguchi, M.7
-
11
-
-
0028826044
-
cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides
-
J. P. Cai, T. Kakuma, T. Tsuzuki and M. Sekiguchi, cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides. Carcinogenesis 16, 2343-2350 (1995).
-
(1995)
Carcinogenesis
, vol.16
, pp. 2343-2350
-
-
Cai, J.P.1
Kakuma, T.2
Tsuzuki, T.3
Sekiguchi, M.4
-
12
-
-
0028858586
-
Mouse MTH1 protein with 8-oxo-7,8-dihydro-29-deoxyguanosine 59-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution
-
T. Kakuma, J. Nishida, T. Tsuzuki and M. Sekiguchi, Mouse MTH1 protein with 8-oxo-7,8-dihydro-29-deoxyguanosine 59-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution. J. Biol. Chem. 270, 25942-25948 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 25942-25948
-
-
Kakuma, T.1
Nishida, J.2
Tsuzuki, T.3
Sekiguchi, M.4
-
13
-
-
0033571211
-
Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism
-
H. Oda, A. Taketomi, R. Maruyama, R. Itoh, K. Nishioka, H. Yakushiji, T. Suzuki, M. Sekiguchi and Y. Nakabeppu, Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism. Nucleic Acids Res. 27, 4335-4343 (1999).
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4335-4343
-
-
Oda, H.1
Taketomi, A.2
Maruyama, R.3
Itoh, R.4
Nishioka, K.5
Yakushiji, H.6
Suzuki, T.7
Sekiguchi, M.8
Nakabeppu, Y.9
-
14
-
-
0030857806
-
Regulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription products
-
H. Oda, Y. Nakabeppu, M. Furuichi and M. Sekiguchi, Regulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription products. J. Biol. Chem. 272, 17843-17850 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 17843-17850
-
-
Oda, H.1
Nakabeppu, Y.2
Furuichi, M.3
Sekiguchi, M.4
-
15
-
-
0028980982
-
Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria
-
D. Kang, J. Nishida, A. Iyama, Y. Nakabeppu, M. Furuichi, T. Fujiwara, M. Sekiguchi and K. Takeshige, Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria. J. Biol. Chem. 270, 14659-14665 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 14659-14665
-
-
Kang, D.1
Nishida, J.2
Iyama, A.3
Nakabeppu, Y.4
Furuichi, M.5
Fujiwara, T.6
Sekiguchi, M.7
Takeshige, K.8
-
16
-
-
0035158162
-
Intracellular distribution of the antimu-tagenic enzyme MTH1 in the liver, kidney and testis of F344 rats and its modulation by cadmium
-
K. S. Kasprzak, Y. Nakabeppu, T. Kakuma, Y. Sakai, K. Tsuruya, M. Sekiguchi, J. M. Ward, B. A. Diwan, K. Nagashima and B. H. Kasprzak, Intracellular distribution of the antimu-tagenic enzyme MTH1 in the liver, kidney and testis of F344 rats and its modulation by cadmium. Exp. Toxicol. Pathol. 53, 325-335 (2001).
-
(2001)
Exp. Toxicol. Pathol
, vol.53
, pp. 325-335
-
-
Kasprzak, K.S.1
Nakabeppu, Y.2
Kakuma, T.3
Sakai, Y.4
Tsuruya, K.5
Sekiguchi, M.6
Ward, J.M.7
Diwan, B.A.8
Nagashima, K.9
Kasprzak, B.H.10
-
17
-
-
33746676294
-
The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal
-
Y. Sakai, H. Oda, D. Yoshimura, M. Furuichi, D. Kang, S. Iwai, T. Hara and Y. Nakabeppu, The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal. J. Mol. Med. 84, 660-670 (2006).
-
(2006)
J. Mol. Med
, vol.84
, pp. 660-670
-
-
Sakai, Y.1
Oda, H.2
Yoshimura, D.3
Furuichi, M.4
Kang, D.5
Iwai, S.6
Hara, T.7
Nakabeppu, Y.8
-
18
-
-
0026486615
-
Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: Sanitization of nucleotide pool
-
J. Y. Mo, H. Maki and M. Sekiguchi, Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool. Proc. Natl. Acad. Sci. USA 89, 11021-11025 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11021-11025
-
-
Mo, J.Y.1
Maki, H.2
Sekiguchi, M.3
-
19
-
-
0033603344
-
The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
-
K. Fujikawa, H. Kamiya, H. Yakushiji, Y. Fujii, Y. Nakabeppu and H. Kasai, The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein. J. Biol. Chem. 274, 18201-18205 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 18201-18205
-
-
Fujikawa, K.1
Kamiya, H.2
Yakushiji, H.3
Fujii, Y.4
Nakabeppu, Y.5
Kasai, H.6
-
20
-
-
0035949687
-
Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
-
T. Tsuzuki, A. Egashira, H. Igarashi, T. Iwakuma, Y. Nakatsuru, Y. Tominaga, H. Kawate, K. Nakao, K. Nakamura and M. Sekiguchi, Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase. Proc. Natl. Acad. Sci. USA 98, 11456-11461 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11456-11461
-
-
Tsuzuki, T.1
Egashira, A.2
Igarashi, H.3
Iwakuma, T.4
Nakatsuru, Y.5
Tominaga, Y.6
Kawate, H.7
Nakao, K.8
Nakamura, K.9
Sekiguchi, M.10
-
21
-
-
0141733067
-
An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress
-
D. Yoshimura, K. Sakumi, M. Ohno, Y. Sakai, M. Furuichi, S. Iwai and Y. Nakabeppu, An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. J. Biol. Chem. 278, 37965-37973 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 37965-37973
-
-
Yoshimura, D.1
Sakumi, K.2
Ohno, M.3
Sakai, Y.4
Furuichi, M.5
Iwai, S.6
Nakabeppu, Y.7
-
22
-
-
39149100596
-
Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death
-
J. Ichikawa, D. Tsuchimoto, S. Oka, M. Ohno, M. Furuichi, K. Sakumi and Y. Nakabeppu, Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death. DNA Repair (Amst.) 7, 418-430 (2008).
-
(2008)
DNA Repair (Amst.)
, vol.7
, pp. 418-430
-
-
Ichikawa, J.1
Tsuchimoto, D.2
Oka, S.3
Ohno, M.4
Furuichi, M.5
Sakumi, K.6
Nakabeppu, Y.7
-
23
-
-
0031012698
-
Organization and expression of the mouse MTH1 gene for preventing transversion mutation
-
H. Igarashi, T. Tsuzuki, T. Kakuma, Y. Tominaga and M. Sekiguchi, Organization and expression of the mouse MTH1 gene for preventing transversion mutation. J. Biol. Chem. 272, 3766-3772 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 3766-3772
-
-
Igarashi, H.1
Tsuzuki, T.2
Kakuma, T.3
Tominaga, Y.4
Sekiguchi, M.5
-
24
-
-
0033974933
-
Activity of the antimu-tagenic enzyme 8-oxo-29-deoxyguanosine 59-triphosphate pyro-phosphohydrolase (8-oxo-dGTPase) in cultured Chinese hamster ovary cells: Effects of cell cycle, proliferation rate, and population density
-
K. Bialkowski and K. S. Kasprzak, Activity of the antimu-tagenic enzyme 8-oxo-29-deoxyguanosine 59-triphosphate pyro-phosphohydrolase (8-oxo-dGTPase) in cultured Chinese hamster ovary cells: effects of cell cycle, proliferation rate, and population density. Free Radic. Biol. Med. 28, 337-344 (2000).
-
(2000)
Free Radic. Biol. Med
, vol.28
, pp. 337-344
-
-
Bialkowski, K.1
Kasprzak, K.S.2
-
25
-
-
5344221553
-
Cellular 8-oxo-7,8-dihydro-29- deoxyguanosine 59-triphosphate pyrophosphohydrolase activity of human and mouse MTH1 proteins does not depend on the proliferation rate
-
K. Bialkowski and K. S. Kasprzak, Cellular 8-oxo-7,8-dihydro-29- deoxyguanosine 59-triphosphate pyrophosphohydrolase activity of human and mouse MTH1 proteins does not depend on the proliferation rate. Free Radic. Biol. Med. 37, 1534-1541 (2004).
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 1534-1541
-
-
Bialkowski, K.1
Kasprzak, K.S.2
-
26
-
-
0032125614
-
A novel assay of 8-oxo-29- deoxyguanosine 59-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity in cultured cells and its use for evaluation of cadmium(II) inhibition of this activity
-
K. Bialkowski and K. S. Kasprzak, A novel assay of 8-oxo-29- deoxyguanosine 59-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity in cultured cells and its use for evaluation of cadmium(II) inhibition of this activity. Nucleic Acids Res. 26, 3194-3201 (1998).
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3194-3201
-
-
Bialkowski, K.1
Kasprzak, K.S.2
-
27
-
-
0032813292
-
Higher activity of 8-oxo-29-deoxyguanosine 59-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) coincides with lower background levels of 8-oxo-29- deoxyguanosine in DNA of fetal compared with maternal mouse organs
-
K. Bialkowski, A. Bialkowska, L. M. Anderson and K. S. Kasprzak, Higher activity of 8-oxo-29-deoxyguanosine 59-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) coincides with lower background levels of 8-oxo-29- deoxyguanosine in DNA of fetal compared with maternal mouse organs. Free Radic. Biol. Med. 27, 90-94 (1999).
-
(1999)
Free Radic. Biol. Med
, vol.27
, pp. 90-94
-
-
Bialkowski, K.1
Bialkowska, A.2
Anderson, L.M.3
Kasprzak, K.S.4
-
28
-
-
29744466425
-
Determination of serum proteins by means of the biuret reaction
-
A. G. Gornall, C. J. Bardawill and M. M. David, Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177, 751-766 (1949).
-
(1949)
J. Biol. Chem
, vol.177
, pp. 751-766
-
-
Gornall, A.G.1
Bardawill, C.J.2
David, M.M.3
-
29
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
P. K. Smith, R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson and D. C. Klenk, Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85 (1985).
-
(1985)
Anal. Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
30
-
-
0034732612
-
Inhibition of antimutagenic enzymes, 8-oxo-dGTPases, by carcinogenic metals. Recent developments
-
K. S. Kasprzak and K. Bialkowski, Inhibition of antimutagenic enzymes, 8-oxo-dGTPases, by carcinogenic metals. Recent developments. J. Inorg. Biochem. 79, 231-236 (2000).
-
(2000)
J. Inorg. Biochem
, vol.79
, pp. 231-236
-
-
Kasprzak, K.S.1
Bialkowski, K.2
-
31
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
U. K. Laemmli, Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685 (1970).
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
32
-
-
0037904752
-
Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides
-
J. P. Cai, T. Ishibashi, Y. Takagi, H. Hayakawa and M. Sekiguchi, Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides. Biochem. Biophys. Res. Commun. 305, 1073-1077 (2003).
-
(2003)
Biochem. Biophys. Res. Commun
, vol.305
, pp. 1073-1077
-
-
Cai, J.P.1
Ishibashi, T.2
Takagi, Y.3
Hayakawa, H.4
Sekiguchi, M.5
-
33
-
-
0032486359
-
Overexpression of hMTH1 mRNA: A molecular marker of oxidative stress in lung cancer cells
-
C. H. Kennedy, R. Cueto, S. A. Belinsky, J. F. Lechner and W. A. Pryor, Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells. FEBS Lett. 429, 17-20 (1998).
-
(1998)
FEBS Lett
, vol.429
, pp. 17-20
-
-
Kennedy, C.H.1
Cueto, R.2
Belinsky, S.A.3
Lechner, J.F.4
Pryor, W.A.5
-
34
-
-
0031978983
-
Immunohistochemical detection of 8-hydroxy-29-deoxyguanosine in paraffin-embedded sections of rat liver after carbon tetrachloride treatment
-
S. Takahashi, M. Hirose, S. Tamano, M. Ozaki, S. Orita, T. Ito, M. Takeuchi, H. Ochi, S. Fukada, H. Kasai and T. Shirai, Immunohistochemical detection of 8-hydroxy-29-deoxyguanosine in paraffin-embedded sections of rat liver after carbon tetrachloride treatment. Toxicol. Pathol. 26, 247-252 (1998).
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 247-252
-
-
Takahashi, S.1
Hirose, M.2
Tamano, S.3
Ozaki, M.4
Orita, S.5
Ito, T.6
Takeuchi, M.7
Ochi, H.8
Fukada, S.9
Kasai, H.10
Shirai, T.11
-
35
-
-
0034607713
-
Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress
-
F. Meyer, E. Fiala and J. Westendorf, Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress. Toxicology 146, 83-92 (2000).
-
(2000)
Toxicology
, vol.146
, pp. 83-92
-
-
Meyer, F.1
Fiala, E.2
Westendorf, J.3
-
36
-
-
0035109485
-
Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos
-
H. N. Kim, Y. Morimoto, T. Tsuda, Y. Ootsuyama, M. Hirohashi, T. Hirano, I. Tanaka, Y. Lim, I. G. Yun and H. Kasai, Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos. Carcinogenesis 22, 265-269 (2001).
-
(2001)
Carcinogenesis
, vol.22
, pp. 265-269
-
-
Kim, H.N.1
Morimoto, Y.2
Tsuda, T.3
Ootsuyama, Y.4
Hirohashi, M.5
Hirano, T.6
Tanaka, I.7
Lim, Y.8
Yun, I.G.9
Kasai, H.10
-
37
-
-
3042769567
-
Comparative study of PM2.5- and PM10-induced oxidative stress in rat lung epithelial cells
-
J. H. Choi, J. S. Kim, Y. C. Kim, Y. S. Kim, N. H. Chung and M. H. Cho, Comparative study of PM2.5- and PM10-induced oxidative stress in rat lung epithelial cells. J. Vet. Sci. 5, 11-18 (2004).
-
(2004)
J. Vet. Sci
, vol.5
, pp. 11-18
-
-
Choi, J.H.1
Kim, J.S.2
Kim, Y.C.3
Kim, Y.S.4
Chung, N.H.5
Cho, M.H.6
-
38
-
-
12844286313
-
Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis
-
H. W. Leung, C. H. Wu, C. H. Lin and H. Z. Lee, Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis. Eur. J. Pharmacol. 508, 77-83 (2005).
-
(2005)
Eur. J. Pharmacol
, vol.508
, pp. 77-83
-
-
Leung, H.W.1
Wu, C.H.2
Lin, C.H.3
Lee, H.Z.4
-
39
-
-
32544458774
-
MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity
-
K. Kajitani, H. Yamaguchi, Y. Dan, M. Furuichi, D. Kang and Y. Nakabeppu, MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity. J. Neurosci. 26, 1688-1698 (2006).
-
(2006)
J. Neurosci
, vol.26
, pp. 1688-1698
-
-
Kajitani, K.1
Yamaguchi, H.2
Dan, Y.3
Furuichi, M.4
Kang, D.5
Nakabeppu, Y.6
-
40
-
-
33746035658
-
The nucleotide pool is a significant target for oxidative stress
-
S. Haghdoost, L. Sjolander, S. Czene and M. Harms-Ringdahl, The nucleotide pool is a significant target for oxidative stress. Free Radic. Biol. Med. 41, 620-626 (2006).
-
(2006)
Free Radic. Biol. Med
, vol.41
, pp. 620-626
-
-
Haghdoost, S.1
Sjolander, L.2
Czene, S.3
Harms-Ringdahl, M.4
-
41
-
-
33745177361
-
Analysis of the in vitro synergistic effect of 5-fluorouracil and cisplatin on cervical carcinoma cells
-
E. K. Yim, S. B. Lee, K. H. Lee, C. J. Kim and J. S. Park, Analysis of the in vitro synergistic effect of 5-fluorouracil and cisplatin on cervical carcinoma cells. Int. J. Gynecol. Cancer 16, 1321-1329 (2006).
-
(2006)
Int. J. Gynecol. Cancer
, vol.16
, pp. 1321-1329
-
-
Yim, E.K.1
Lee, S.B.2
Lee, K.H.3
Kim, C.J.4
Park, J.S.5
-
42
-
-
34547441808
-
Measurement of 7,8-dihydro-8-oxo-29-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry
-
S. S. Hah, J. M. Mundt, H. M. Kim, R. A. Sumbad, K. W. Turteltaub and P. T. Henderson, Measurement of 7,8-dihydro-8-oxo-29-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry. Proc. Natl. Acad. Sci. USA 104, 11203-11208 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11203-11208
-
-
Hah, S.S.1
Mundt, J.M.2
Kim, H.M.3
Sumbad, R.A.4
Turteltaub, K.W.5
Henderson, P.T.6
-
43
-
-
0032709404
-
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease
-
H. Shimura-Miura, N. Hattori, D. Kang, K. Miyako, Y. Nakabeppu and Y. Mizuno, Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease. Ann. Neurol. 46, 920-924 (1999).
-
(1999)
Ann. Neurol
, vol.46
, pp. 920-924
-
-
Shimura-Miura, H.1
Hattori, N.2
Kang, D.3
Miyako, K.4
Nakabeppu, Y.5
Mizuno, Y.6
-
44
-
-
0035319295
-
Accumulation of 8-oxo-29-deoxyguanosine and increased expression of hMTH1 protein in brain tumors
-
T. Iida, A. Furuta, M. Kawashima, J. Nishida, Y. Nakabeppu and T. Iwaki, Accumulation of 8-oxo-29-deoxyguanosine and increased expression of hMTH1 protein in brain tumors. Neuro. Oncol. 3, 73-81 (2001).
-
(2001)
Neuro. Oncol
, vol.3
, pp. 73-81
-
-
Iida, T.1
Furuta, A.2
Kawashima, M.3
Nishida, J.4
Nakabeppu, Y.5
Iwaki, T.6
-
45
-
-
0035846652
-
8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts
-
H. Tsutsui, T. Ide, T. Shiomi, D. Kang, S. Hayashidani, N. Suematsu, J. Wen, H. Utsumi, N. Hamasaki and A. Takeshita, 8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts. Circulation 104, 2883-2885 (2001).
-
(2001)
Circulation
, vol.104
, pp. 2883-2885
-
-
Tsutsui, H.1
Ide, T.2
Shiomi, T.3
Kang, D.4
Hayashidani, S.5
Suematsu, N.6
Wen, J.7
Utsumi, H.8
Hamasaki, N.9
Takeshita, A.10
-
46
-
-
12244286790
-
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias
-
K. Kuwano, N. Nakashima, I. Inoshima, N. Hagimoto, M. Fujita, M. Yoshimi, T. Maeyama, N. Hamada, K. Watanabe and N. Hara, Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias. Eur. Respir. J. 21, 232-240 (2003).
-
(2003)
Eur. Respir. J
, vol.21
, pp. 232-240
-
-
Kuwano, K.1
Nakashima, N.2
Inoshima, I.3
Hagimoto, N.4
Fujita, M.5
Yoshimi, M.6
Maeyama, T.7
Hamada, N.8
Watanabe, K.9
Hara, N.10
-
47
-
-
0038705959
-
Increase of human MTH1 and decrease of 8-hydroxydeoxyguanosine in leukocyte DNA by acute and chronic exercise in healthy male subjects
-
Y. Sato, H. Nanri, M. Ohta, H. Kasai and M. Ikeda, Increase of human MTH1 and decrease of 8-hydroxydeoxyguanosine in leukocyte DNA by acute and chronic exercise in healthy male subjects. Biochem. Biophys. Res. Commun. 305, 333-338 (2003).
-
(2003)
Biochem. Biophys. Res. Commun
, vol.305
, pp. 333-338
-
-
Sato, Y.1
Nanri, H.2
Ohta, M.3
Kasai, H.4
Ikeda, M.5
-
48
-
-
0037143598
-
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques
-
W. Martinet, M. W. Knaapen, G. R. De Meyer, A. G. Herman and M. M. Kockx, Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques. Circulation 106, 927-932 (2002).
-
(2002)
Circulation
, vol.106
, pp. 927-932
-
-
Martinet, W.1
Knaapen, M.W.2
De Meyer, G.R.3
Herman, A.G.4
Kockx, M.M.5
-
49
-
-
18544392795
-
Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma
-
C. Jungst, B. Cheng, R. Gehrke, V. Schmitz, H. D. Nischalke, J. Ramakers, P. Schramel, P. Schirmacher, T. Sauerbruch and W. H. Caselmann, Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology 39, 1663-1672 (2004).
-
(2004)
Hepatology
, vol.39
, pp. 1663-1672
-
-
Jungst, C.1
Cheng, B.2
Gehrke, R.3
Schmitz, V.4
Nischalke, H.D.5
Ramakers, J.6
Schramel, P.7
Schirmacher, P.8
Sauerbruch, T.9
Caselmann, W.H.10
-
50
-
-
0035903269
-
Expression of hMTH1 in the hippocampi of control and Alzheimer's disease
-
A. Furuta, T. Iida, Y. Nakabeppu and T. Iwaki, Expression of hMTH1 in the hippocampi of control and Alzheimer's disease. Neuroreport 12, 2895-2899 (2001).
-
(2001)
Neuroreport
, vol.12
, pp. 2895-2899
-
-
Furuta, A.1
Iida, T.2
Nakabeppu, Y.3
Iwaki, T.4
-
51
-
-
4344669657
-
Activation of nuclear factor kappaB in vivo selectively protects the murine small intestine against ionizing radiation-induced damage
-
Y. Wang, A. Meng, H. Lang, S. A. Brown, J. L. Konopa, M. S. Kindy, R. A. Schmiedt, J. S. Thompson and D. Zhou, Activation of nuclear factor kappaB in vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Res. 64, 6240-6246 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 6240-6246
-
-
Wang, Y.1
Meng, A.2
Lang, H.3
Brown, S.A.4
Konopa, J.L.5
Kindy, M.S.6
Schmiedt, R.A.7
Thompson, J.S.8
Zhou, D.9
|