Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos

Carcinogenesis

Volumn 22, Issue 2, 2001, Pages 265-269

  Kim, Heung Nam ^a   Morimoto, Yasuo ^a   Tsuda, Tohru ^a   Ootsuyama, Yuko ^a   Hirohashi, Masami ^a   Hirano, Takeshi ^a   Tanaka, Isamu ^a   Lim, Young ^b   Yun, Im Gyung ^c   Kasai, Hiroshi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b The Catholic University of Korea   (South Korea)

^c Korean Industrial Health Association   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CROCIDOLITE; DNA; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; MESSENGER RNA;

ARTICLE; CARCINOGENICITY; CELL DAMAGE; CONTROLLED STUDY; DNA REPAIR; ELECTROCHEMICAL DETECTION; ENZYME ACTIVITY; ENZYME ASSAY; EPITHELIUM CELL; EXPOSURE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0035109485     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/22.2.265     Document Type: Article

References (33)

1. Mechanisms in the pathogenesis of asbestosis and silicosis
2. Fiber toxicology
3. Calcium chelator Quin-2 prevents crocidolite-induced DNA strand breakage in human white blood cells
4. Evidence supporting a role for active oxygen species in asbestos-induced toxicity and lung disease
5. Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy
6. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
7. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
8. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions
9. Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine
10. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily
11. Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue
12. Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage
13. Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis
14. Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria
15. In-vitro biological study to evaluate the toxic potentials of fibrous materials
16. Increased 8-hydroxyguanine levels in DNA and its repair activity in rat kidney after administration of a renal carcinogen, ferric nitrilotriacetate
17. Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue
18. Ubiquitous presence in mammalian cells of enzymatic activity specifically cleaving 8-hydroxyguanine-containing DNA
19. Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
20. Synthesis and processing of the precursor for human mangano-superoxide dismutase
21. Quantitative approaches for studying gene expression
22. Relationship between asbestos exposures and 8-hydroxydeoxyguanosine levels in leukocytic DNA of workers at a Chinese asbestos-material plant
23. Crocidolite asbestos increased 8-hydroxydeoxyguanosine levels in cellular DNA of a human promyelocytic leukemia cell line, HL60
24. Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos
25. Inductions of oxidative DNA damage and mesothelioma by crocidolite, with special reference to the presence of iron inside and outside of asbestos fiber
26. Participation of nitric oxide and iron in the oxidation of DNA in asbestos-treated human lung epithelial cells
27. Determination of carcinogenic potential of mineral fibers by 8-hydroxydeoxyguanosine as a marker of oxidative DNA damage in mammalian cells
28. Increase of 8-hydroxyguanine in DNA and its repair activity in hamster and rat lung after intratracheal instillation of crocidolite asbestos
29. Asbestos increases mammalian AP-endonuclease gene expression, protein levels and enzyme activity in mesothelial cells
30. Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase
31. The presence of two distinct 8-oxoguanine repair enzymes in human cells: Their potential complementary roles in preventing mutation
32. Overexpression of hMTH1 mRNA: A molecular market of oxidative stress in lung cancer cells
33. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis