Agonist-biased signaling via proteinase activated receptor-2: Differential activation of calcium and mitogen-activated protein kinase pathways

Molecular Pharmacology

Volumn 76, Issue 4, 2009, Pages 791-801

  Ramachandran, Rithwik ^a   Mihara, Koichiro ^a   Mathur, Maneesh ^b   Rochdi, Moulay Driss ^c   Bouvier, Michel ^c   DeFea, Kathryn ^b   Hollenberg, Morley D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ALANINE; ALANYLALANYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; AMIDE; BETA ARRESTIN 1; BETA ARRESTIN 2; CALCIUM; DOXYCYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LEUCINE; LEUCYLSERYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; N CYCLOHEXYL 1 (2,4 DICHLOROPHENYL) 1,4 DIHYDRO 6 METHYLINDENO[1,2 C]PYRAZOLE 3 CARBOXAMIDE; PERTUSSIS TOXIN; PROTEINASE ACTIVATED RECEPTOR 2; SERINE; SERYLLEUCYLALANYLALANYLALANYLALANINAMIDE; TRANS N (4 PYRIDYL) 4 (1 AMINOETHYL)CYCLOHEXANECARBOXAMIDE; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CALCIUM SIGNALING; CELL LINE; ENZYME INHIBITORS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; RECEPTOR, PAR-2; TRANSCRIPTIONAL ACTIVATION; TRYPSIN;

EID: 70349324342     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.055509     Document Type: Article

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