Iron overload alters iron-regulatory genes and proteins, down-regulates osteoblastic phenotype, and is associated with apoptosis in fetal rat calvaria cultures

Bone

Volumn 45, Issue 5, 2009, Pages 972-979

  Messer, Jonathan G ^a   Kilbarger, Amy K ^b   Erikson, Keith M ^a   Kipp, Deborah E ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone nodules; Ferritin; Ferrous sulfate; Osteocalcin; Transferrin receptor

Indexed keywords

FERRITIN; FERROUS SULFATE; IRON; REGULATOR PROTEIN; TRANSFERRIN RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MINERALIZATION; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; FETUS; HEAVY CHAIN; INTRACELLULAR SPACE; IRON METABOLISM; IRON OVERLOAD; LIGHT CHAIN; MARKER GENE; MICROSCOPY; NONHUMAN; OSTEOBLAST; PHENOTYPE; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REGULATOR GENE;

ANIMALS; ANNEXIN A5; APOPTOSIS; BIOLOGICAL MARKERS; CELL NUCLEUS; CELLS, CULTURED; DOWN-REGULATION; FEMALE; FERROUS COMPOUNDS; FETUS; IN SITU NICK-END LABELING; IRON; IRON OVERLOAD; OSTEOBLASTS; PHENOTYPE; PROPIDIUM; RATS; RATS, SPRAGUE-DAWLEY; SKULL; STAINING AND LABELING;

EID: 70349282987     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.07.073     Document Type: Article

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