Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate

Journal of Neurochemistry

Volumn 88, Issue 5, 2004, Pages 1194-1202

  Hoepken, Hans H ^a,b   Korten, Till ^a   Robinsont, Stephen R ^b   Dringen, Ralf ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Glia; Iron; Oxidative stress; Radicals

Indexed keywords

CYCLOHEXIMIDE; DEFEROXAMINE; FERRIC AMMONIUM CITRATE; FERRITIN; IRON; IRON CHELATING AGENT; LACTATE DEHYDROGENASE; PROTEIN SYNTHESIS INHIBITOR; REACTIVE OXYGEN METABOLITE; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ARTICLE; ASTROCYTE; BIOACCUMULATION; BIOSYNTHESIS; BRAIN CELL; CATALYST; CELL FUNCTION; CELL LEVEL; CELL LOSS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPATHOGENIC EFFECT; ENZYME ACTIVITY; ENZYME ASSAY; IMMUNOCYTOCHEMISTRY; INTERNALIZATION; IRON METABOLISM; IRON STORAGE; IRON TRANSPORT; NERVE CELL CULTURE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RAT; REGULATORY MECHANISM; UPREGULATION;

ANIMALS; ASTROCYTES; CELL SURVIVAL; CELLS, CULTURED; CYCLOHEXIMIDE; DEFEROXAMINE; FERRIC COMPOUNDS; FERRITINS; IRON; IRON CHELATING AGENTS; L-LACTATE DEHYDROGENASE; PROTEIN SYNTHESIS INHIBITORS; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; RECEPTORS, TRANSFERRIN;

ANIMALIA;

EID: 1442323987     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02236.x     Document Type: Article

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