Oxidative stress, β-cell apoptosis, and decreased insulin secretory capacity in mouse models of hemochromatosis

Endocrinology

Volumn 145, Issue 11, 2004, Pages 5305-5312

  Cooksey, Robert C ^a,b   Jouihan, Hani A ^b   Ajioka, Richard S ^b   Hazel, Mark W ^b   Jones, Deborah L ^b   Kushner, James P ^b   McClain, Donald A ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; CASPASE 3; CELL MARKER; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; IRON; MESSENGER RNA;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL SIZE; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; ENZYME ACTIVATION; GENE; GENE DELETION; GENE MUTATION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HEMOCHROMATOSIS; HFE GENE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; IRON INTAKE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN MODIFICATION;

AGE FACTORS; ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; GLUCOSE INTOLERANCE; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; INSULIN; IRON; ISLETS OF LANGERHANS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 9244230038     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0392     Document Type: Article

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