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Volumn 7, Issue 19, 2009, Pages 3982-3990
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Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3
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Author keywords
[No Author keywords available]
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Indexed keywords
ALDOXIMES;
GALECTIN-7;
GALECTINS;
HIGH AFFINITY;
N-TERMINALS;
GLUCOSE;
GALECTIN 3;
HYDROXYLAMINE;
OXIME;
TRIAZOLE DERIVATIVE;
ACYLATION;
ARTICLE;
BINDING SITE;
CHEMICAL STRUCTURE;
CHEMISTRY;
CONFORMATION;
DRUG ANTAGONISM;
DRUG DEVELOPMENT;
ENZYME SPECIFICITY;
METABOLISM;
OXIDATION REDUCTION REACTION;
PROTEIN BINDING;
PROTEIN TERTIARY STRUCTURE;
SYNTHESIS;
ACYLATION;
BINDING SITES;
DRUG DISCOVERY;
GALECTIN 3;
HYDROXYLAMINES;
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
OXIDATION-REDUCTION;
OXIMES;
PROTEIN BINDING;
PROTEIN STRUCTURE, TERTIARY;
SUBSTRATE SPECIFICITY;
TRIAZOLES;
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EID: 70349281538
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/b909091f Document Type: Article |
Times cited : (51)
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References (46)
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