Synthesis of a phenyl thio-ß-D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: Discovery of efficient and selective monosaccharide inhibitors of galectin-7

Organic and Biomolecular Chemistry

Volumn 3, Issue 10, 2005, Pages 1922-1932

  Cumpstey, Ian ^a   Carlsson, Susanne ^a   Leffler, Hakon ^a   Nilsson, Ulf J ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BIOASSAY; POLARIZATION; REACTION KINETICS; REDUCTION; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL); TUMORS;

AROMATIC NUCLEOPHILIC SUBSTITUTION; GALECTIN-7; MONOSACCHARIDE INHIBITORS; THIOLS;

PROTEINS;

1 FLUORO 2,4 DINITROBENZENE; 1,5 DIFLUORO 2,4 DINITROBENZENE; 1,5-DIFLUORO-2,4-DINITROBENZENE; DRUG DERIVATIVE; GALECTIN; LGALS7 PROTEIN, HUMAN; MONOSACCHARIDE; PHENYL THIO BETA D GALACTOPYRANOSIDE; PHENYL THIO-BETA-D-GALACTOPYRANOSIDE;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

DINITROFLUOROBENZENE; GALECTINS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MONOSACCHARIDES;

EID: 19944425218     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b502354h     Document Type: Article

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