Protein subtype-targeting through ligand epimerization: Talose-selectivity of galectin-4 and galectin-8

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 13, 2008, Pages 3691-3694

  Öberg, Christopher T ^a   Blanchard, Helen ^b   Leffler, Hakon ^a   Nilsson, Ulf J ^a  

^a LUND UNIVERSITY   (Sweden)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

Galectin; Inhibitor; Talopyranose

Indexed keywords

AMINO ACID DERIVATIVE; ARGININE DERIVATIVE; BETA DEXTRO TALOPYRANOSIDE DERIVATIVE; CHLORIDE; DEXTRO GALACTOPYRANOSE; DEXTRO TALOPYRANOSE; ENZYME INHIBITOR; GALACTOSE; GALACTOSIDE; GALECTIN 1; GALECTIN 2; GALECTIN 3; GALECTIN 4; GALECTIN 8; IODINE; OXYGEN;

ACETYLATION; ARTICLE; BINDING AFFINITY; DERIVATIZATION; EPIMERIZATION; FLUORESCENCE POLARIZATION; HUMAN; HYDROGEN BOND; HYDROLYSIS; IN VITRO STUDY; OXIDATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TARGETING; SEQUENCE HOMOLOGY;

BINDING SITES; GALACTOSE; GALECTIN 1; GALECTIN 3; GALECTIN 4; GALECTINS; HUMANS; LACTONES; LIGANDS; MODELS, CHEMICAL; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; PYRANS; SPECTROMETRY, FLUORESCENCE;

EID: 44749093873     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.066     Document Type: Article

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