메뉴 건너뛰기




Volumn 84, Issue 5, 2009, Pages 264-270

Interaction of thiazolidinediones (glitazones) with the ATP-Binding cassette transporters P-glycoprotein and breast cancer resistance protein

Author keywords

Breast cancer resistance protein; Glitazone; P glycoprotein; Thiazolidinedione

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ABC TRANSPORTER; ANTIDIABETIC AGENT; BREAST CANCER RESISTANCE PROTEIN; COMPLEMENTARY DNA; FUMITREMORGIN C; GLITAZONE DERIVATIVE; GLYCOPROTEIN P; LACTATE DEHYDROGENASE; MESSENGER RNA; PIOGLITAZONE; RIFAMPICIN; ROSIGLITAZONE; TROGLITAZONE; VERLUKAST; ZOSUQUIDAR;

EID: 70349264523     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000241734     Document Type: Article
Times cited : (32)

References (48)
  • 1
    • 43149118341 scopus 로고    scopus 로고
    • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
    • Szaka ́cs G, Váradi A, Ozvegy-Laczka C, Sarkadi B: The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discov Today 2008; 13: 379-393.
    • (2008) Drug Discov Today , vol.13 , pp. 379-393
    • Szaka ́cs, G.1    Váradi, A.2    Ozvegy-Laczka, C.3    Sarkadi, B.4
  • 4
    • 0032101275 scopus 로고    scopus 로고
    • The pharmacological role of P-glycoprotein in the intestinal epithelium
    • Van Asperen J, Van Tellingen O, Beijnen JH: The pharmacological role of P-glycoprotein in the intestinal epithelium. Pharmacol Res 1998; 37:429-435.
    • (1998) Pharmacol Res , vol.37 , pp. 429-435
    • Van Asperen, J.1    Van Tellingen, O.2    Beijnen, J.H.3
  • 5
    • 0031691234 scopus 로고    scopus 로고
    • The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs
    • Kusuhara H, Suzuki H, Sugiyama Y: The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs. J Pharm Sci 1998; 87: 1025-1040.
    • (1998) J Pharm Sci , vol.87 , pp. 1025-1040
    • Kusuhara, H.1    Suzuki, H.2    Sugiyama, Y.3
  • 6
    • 0033795486 scopus 로고    scopus 로고
    • Potential role of P-glycoprotein in affecting hepatic metabolism of drugs
    • Chiou WL, Chung SM, Wu TC: Potential role of P-glycoprotein in affecting hepatic metabolism of drugs. Pharm Res 2000; 17: 903-905.
    • (2000) Pharm Res , vol.17 , pp. 903-905
    • Chiou, W.L.1    Chung, S.M.2    Wu, T.C.3
  • 7
    • 0033328139 scopus 로고    scopus 로고
    • The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions
    • Yu DK: The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions. J Clin Pharmacol 1999; 39: 1203-1211.
    • (1999) J Clin Pharmacol , vol.39 , pp. 1203-1211
    • Yu, D.K.1
  • 8
    • 27644480743 scopus 로고    scopus 로고
    • Role of the breast cancer resistance protein (ABCG2) in drug transport
    • Mao Q, Unadkat JD: Role of the breast cancer resistance protein (ABCG2) in drug transport. AAPS J 2005; 7:E118-E133.
    • (2005) AAPS J , vol.7
    • Mao, Q.1    Unadkat, J.D.2
  • 10
    • 30344444454 scopus 로고    scopus 로고
    • The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins
    • Van Herwaarden AE, Schinkel AH: The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins. Trends Pharmacol Sci 2006; 27: 10-16.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 10-16
    • Van Herwaarden, A.E.1    Schinkel, A.H.2
  • 11
    • 29744441900 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp1/ Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp- P-1 but also mediates their secretion into breast milk
    • Van Herwaarden AE, Wagenaar E, Karnekamp B, Merino G, Jonker JW, Schinkel AH: Breast cancer resistance protein (Bcrp1/ Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp- P-1 but also mediates their secretion into breast milk. Carcinogenesis 2006; 27: 123-130.
    • (2006) Carcinogenesis , vol.27 , pp. 123-130
    • Van Herwaarden, A.E.1    Wagenaar, E.2    Karnekamp, B.3    Merino, G.4    Jonker, J.W.5    Schinkel, A.H.6
  • 12
    • 4143142207 scopus 로고    scopus 로고
    • Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: Potential role for breast cancer resistance protein in clinical drug-drug interactions
    • Breedveld P, Zelcer N, Pluim D, Sönmezer O, Tibben MM, Beijnen JH, Schinkel AH, van Tellingen O, Borst P, Schellens JH: Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res 2004; 64: 5804-5811.
    • (2004) Cancer Res , vol.64 , pp. 5804-5811
    • Breedveld, P.1    Zelcer, N.2    Pluim, D.3    Sönmezer, O.4    Tibben, M.M.5    Beijnen, J.H.6    Schinkel, A.H.7    Van Tellingen, O.8    Borst, P.9    Schellens, J.H.10
  • 13
    • 59149084957 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor gamma agonists as insulin sensitizers: From the discovery to recent progress
    • Cho N, Momose Y: Peroxisome proliferatoractivated receptor gamma agonists as insulin sensitizers: from the discovery to recent progress. Curr Top Med Chem 2008; 8: 1483-1507.
    • (2008) Curr Top Med Chem , vol.8 , pp. 1483-1507
    • Cho, N.1    Momose, Y.2
  • 14
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Järvinen H: Thiazolidinediones. N Engl J Med 2004; 351: 1106-1118.
    • (2004) N Engl J Med , vol.351 , pp. 1106-1118
    • Yki-Järvinen, H.1
  • 15
    • 0004365871 scopus 로고    scopus 로고
    • From the Food and Drug Administration
    • Henney JE: From the Food and Drug Administration. JAMA 2000; 283: 2228.
    • (2000) JAMA , vol.283 , pp. 2228
    • Henney, J.E.1
  • 17
    • 33846424578 scopus 로고    scopus 로고
    • Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect
    • Enokizono J, Kusuhara H, Sugiyama Y: Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect. Drug Metab Dispos 2007; 35: 209-214.
    • (2007) Drug Metab Dispos , vol.35 , pp. 209-214
    • Enokizono, J.1    Kusuhara, H.2    Sugiyama, Y.3
  • 19
    • 0026014503 scopus 로고
    • In vivo circumvention of P-glycoprotein-mediated multidrug resistance of tumor cells with SDZ PSC 833
    • Boesch D, Gavériaux C, Jachez B, Pourtier- Manzanedo A, Bollinger P, Loor F: In vivo circumvention of P-glycoprotein-mediated multidrug resistance of tumor cells with SDZ PSC 833. Cancer Res 1991; 51: 4226-4233.
    • (1991) Cancer Res , vol.51 , pp. 4226-4233
    • Boesch, D.1    Gavériaux, C.2    Jachez, B.3    Pourtier- Manzanedo, A.4    Bollinger, P.5    Loor, F.6
  • 20
    • 34047178340 scopus 로고    scopus 로고
    • Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein
    • DOI 10.1016/j.bcp.2007.01.027, PII S0006295207000615
    • Storch CH, Theile D, Lindenmaier H, Haefeli WE, Weiss J: Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein. Biochem Pharmacol 2007; 73: 1573-1581. (Pubitemid 46527547)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.10 , pp. 1573-1581
    • Storch, C.H.1    Theile, D.2    Lindenmaier, H.3    Haefeli, W.E.4    Weiss, J.5
  • 21
    • 11844284860 scopus 로고    scopus 로고
    • Human breast cancer resistance protein: Interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo(4,5- b )pyridine, and transport of cimetidine
    • Pavek P, Merino G, Wagenaar E, Bolscher E, Novotna M, Jonker JW, Schinkel AH: Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo(4,5- b )pyridine, and transport of cimetidine. J Pharmacol Exp Ther 2005; 312: 144-152.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 144-152
    • Pavek, P.1    Merino, G.2    Wagenaar, E.3    Bolscher, E.4    Novotna, M.5    Jonker, J.W.6    Schinkel, A.H.7
  • 22
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J: Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res 1982; 42: 3858-3863.
    • (1982) Cancer Res , vol.42 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 25
    • 34548843672 scopus 로고    scopus 로고
    • Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro
    • Storch CH, Ehehalt R, Haefeli WE, Weiss J: Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther 2007; 323: 257-264.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 257-264
    • Storch, C.H.1    Ehehalt, R.2    Haefeli, W.E.3    Weiss, J.4
  • 28
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: 1-11.
    • (2002) Genome Biol , vol.3 , pp. 1-11
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 29
    • 23744464363 scopus 로고    scopus 로고
    • Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver
    • Albermann N, Schmitz-Winnenthal FH, Z'graggen K, Volk C, Hoffmann MM, Haefeli WE, Weiss J: Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem Pharmacol 2005; 70: 949-958.
    • (2005) Biochem Pharmacol , vol.70 , pp. 949-958
    • Albermann, N.1    Schmitz-Winnenthal, F.H.2    Z'Graggen, K.3    Volk, C.4    Hoffmann, M.M.5    Haefeli, W.E.6    Weiss, J.7
  • 31
    • 31044448805 scopus 로고    scopus 로고
    • Evaluation of inhibitory potencies for compounds inhibiting P-glycoprotein but without maximum effects: F 2 values
    • Weiss J, Haefeli WE: Evaluation of inhibitory potencies for compounds inhibiting P-glycoprotein but without maximum effects: F 2 values. Drug Metab Dispos 2006; 34: 203-207.
    • (2006) Drug Metab Dispos , vol.34 , pp. 203-207
    • Weiss, J.1    Haefeli, W.E.2
  • 32
    • 0035049927 scopus 로고    scopus 로고
    • Using thiazolidinediones: Rosiglitazone and pioglitazone in clinical practice
    • Peters AL: Using thiazolidinediones: rosiglitazone and pioglitazone in clinical practice. Am J Manag Care 2001; 7:S87-S95.
    • (2001) Am J Manag Care , vol.7
    • Peters, A.L.1
  • 34
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K: Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356: 2457-2471. (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 35
    • 34548580881 scopus 로고    scopus 로고
    • Long-term risk of cardiovascular events with rosiglitazone: A meta-analysis
    • Singh S, Loke YK, Furberg CD: Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis. JAMA 2007; 298: 1189-1195.
    • (2007) JAMA , vol.298 , pp. 1189-1195
    • Singh, S.1    Loke, Y.K.2    Furberg, C.D.3
  • 36
    • 37849035246 scopus 로고    scopus 로고
    • Weighing up the cardiovascular benefits of thiazolidinedione therapy: The impact of increased risk of heart failure
    • Erdmann E, Wilcox RG: Weighing up the cardiovascular benefits of thiazolidinedione therapy: the impact of increased risk of heart failure. Eur Heart J 2008; 29: 12-20.
    • (2008) Eur Heart J , vol.29 , pp. 12-20
    • Erdmann, E.1    Wilcox, R.G.2
  • 37
    • 33846168144 scopus 로고    scopus 로고
    • Pharmacokinetic interactions with thiazolidinediones
    • Scheen AJ: Pharmacokinetic interactions with thiazolidinediones. Clin Pharmacokinet 2007; 46: 1-12.
    • (2007) Clin Pharmacokinet , vol.46 , pp. 1-12
    • Scheen, A.J.1
  • 41
    • 27144483358 scopus 로고    scopus 로고
    • Identification of BCRP as transporter of benzo[ a ]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
    • Ebert B, Seidel A, Lampen A: Identification of BCRP as transporter of benzo[ a ]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. Carcinogenesis 2005; 26: 1754-1763.
    • (2005) Carcinogenesis , vol.26 , pp. 1754-1763
    • Ebert, B.1    Seidel, A.2    Lampen, A.3
  • 42
    • 35348846046 scopus 로고    scopus 로고
    • Transcriptional upregulation of breast cancer resistance protein by 17betaestradiol in ERalpha-positive MCF-7 breast cancer cells
    • Zhang Y, Zhou G, Wang H, Zhang X, Wei F, Cai Y, Yin D: Transcriptional upregulation of breast cancer resistance protein by 17betaestradiol in ERalpha-positive MCF-7 breast cancer cells. Oncology 2006; 71: 446-455.
    • (2006) Oncology , vol.71 , pp. 446-455
    • Zhang, Y.1    Zhou, G.2    Wang, H.3    Zhang, X.4    Wei, F.5    Cai, Y.6    Yin, D.7
  • 43
    • 0033022510 scopus 로고    scopus 로고
    • Troglitazone: A review of its use in the management of type 2 diabetes mellitus
    • Plosker GL, Faulds D: Troglitazone: a review of its use in the management of type 2 diabetes mellitus. Drugs 1999; 57: 409-438.
    • (1999) Drugs , vol.57 , pp. 409-438
    • Plosker, G.L.1    Faulds, D.2
  • 44
    • 0033851704 scopus 로고    scopus 로고
    • Pioglitazone
    • Gillies PS, Dunn C: Pioglitazone. Drugs 2000; 60: 333-343.
    • (2000) Drugs , vol.60 , pp. 333-343
    • Gillies, P.S.1    Dunn, C.2
  • 45
    • 36849081979 scopus 로고    scopus 로고
    • Rosiglitazone: A review of its use in type 2 diabetes mellitus
    • Deeks ED, Keam SJ: Rosiglitazone: a review of its use in type 2 diabetes mellitus. Drugs 2007; 67: 2747-2779.
    • (2007) Drugs , vol.67 , pp. 2747-2779
    • Deeks, E.D.1    Keam, S.J.2
  • 47
    • 0033732180 scopus 로고    scopus 로고
    • Rosiglitazone does not affect the steadystate pharmacokinetics of digoxin
    • Di Cicco RA, Miller AK, Patterson S, Freed MI: Rosiglitazone does not affect the steadystate pharmacokinetics of digoxin. J Clin Pharmacol 2000; 40: 1516-1521.
    • (2000) J Clin Pharmacol , vol.40 , pp. 1516-1521
    • Di Cicco, R.A.1    Miller, A.K.2    Patterson, S.3    Freed, M.I.4
  • 48
    • 1542286164 scopus 로고    scopus 로고
    • Effect of rifampicin on the pharmacokinetics of rosiglitazone in healthy subjects
    • Park JY, Kim KA, Kang MH, Kim SL, Shin JG: Effect of rifampicin on the pharmacokinetics of rosiglitazone in healthy subjects. Clin Pharmacol Ther 2004; 75: 157-162.
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 157-162
    • Park, J.Y.1    Kim, K.A.2    Kang, M.H.3    Kim, S.L.4    Shin, J.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.