Propofol increases agonist efficacy at the GABA(A) receptor

Brain Research

Volumn 852, Issue 2, 2000, Pages 344-348

  O'Shea, Sean M ^a   Wong, Lily C ^a   Harrison, Neil L ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Allosteric modulator; Anesthetic; Apparent affinity; GABA(A) receptor; HEK 293; Ligand gated ion channel; Partial agonist; Recombinant GABA(A) R; Whole cell voltage clamp

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 PIPERIDINESULFONIC ACID; ION CHANNEL; MIDAZOLAM; PARTIAL AGONIST; PROPOFOL;

AGONIST; ALLOSTERISM; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR OCCUPANCY;

ALLOSTERIC REGULATION; ANESTHETICS, INTRAVENOUS; CELLS, CULTURED; DRUG SYNERGISM; GABA AGONISTS; GABA MODULATORS; HUMANS; ION CHANNEL GATING; KIDNEY; LIGANDS; MIDAZOLAM; PATCH-CLAMP TECHNIQUES; PIPERIDINES; PROPOFOL; RECEPTORS, GABA-A;

EID: 0033987352     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02151-4     Document Type: Article

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