Mitochondrial energy metabolism in the left ventricular tissue of spontaneously hypertensive rats: Abnormalities in both adeninenucleotide and phosphate translocators and enzyme adenylatekinase and creatine-phosphokinase activities

Clinical and Experimental Hypertension

Volumn 20, Issue 3, 1998, Pages 345-358

  Seccia, T M ^a   Atlante, A ^a   Vulpis, V ^a   Marra, E ^a   Passarella, S ^a   Pirrelli, A ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Energy metabolism; Hypertension; Left ventricular hypertrophy; Mitochondria

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; CREATINE KINASE; PHOSPHATE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ENERGY METABOLISM; ENZYME ACTIVITY; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE HYPERTROPHY; HYPERTENSION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0031900454     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.3109/10641969809052126     Document Type: Article

References (40)

1. Harris DA, Das AM. Control of mitochondrial ATP synthesis in the heart. Biochem J 1991; 280: 561-573
2. Aussedat J, Lortet S, Ray A, Rossi A, Heckman M, Zimmer HG, Vincent M, Sassart J. Energy metabolism of the hypertrophied heart studied by 31P nuclear magnetic resonance. Cardioscience 1992; 3: 233-239
3. Sordahl LA, McCollum WB, Wood WG, Schwartz A. Mitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure. Am J Physiol 1973; 214 (3): 497-502
4. Taegtmeyer H, Hems R, Krebs HA. Utilization of energy-providing substrates in the isolated working rat heart. Biochem J 1980; 186: 701-711
5. Bladergroen MR, Takei H, Christopher TD, Cummings RG, Blanchard SM, Lowe JE. Accelerated transmural gradients of energy compound metabolism resulting from left ventricular hypertrophy. J Thorac Cardiovasc Surg 1990; 100: 506-516
6. Gibbs CL, Wendt IR, Kotsanas G, Young IR. Mechanical, energetic, and biochemical changes in long-term volume overload of rabbit heart. Am J Physiol 1992; 262 (Heart Circ Physiol 31): H819-H827
7. Das AM, Harris DA Defects in regulation of mitochondrial ATP synthase in cardiomyocytes from spontaneously hypertensive rats. Am J Physiol 1990; 259 (Heart Circ Physiol 28): H1264-H1269
8. Tokoro T, Ito H, Suzuki T. Alterations in mitochondrial DNA and enzyme activities in hypertrophied myocardium of stroke-prone SHRS. Clin and Exper Hypertens 1996; 18: 595-606
9. Tomanek RJ, Searls JC, Lachenbruch PA. Quantitative changes in the capillary bed during developing, peak, and stabilized cardiac hypertrophy in the spontaneously hypertensive rat. Circ Res 1982; 51: 295-304
10. Engelmann GL, Vitullo JC, Gerrity RG. Age-related changes in ploidy levels and biochemical parameters in cardiac myocytes isolated from spontaneously hypertensive rats. Circ Res 1986; 58: 137-147
11. Passarella S, Palmieri F, Quagliariello E. The transport of oxaloacetate in isolated mitochondria. Arch Biochem Biophys 1977; 180: 160-168
12. Waddel WJ, Hill C. A simple ultraviolet spectrophotometric method for the determination of protein. J Lab Clin Med 1956; 48: 311-314
13. Passarella S, Ostuni A, Atlante A, Quagliariello E. Increase in the ADP/ATP exchange in rat liver mitochondria irradiated in vitro by helium-neon laser. Biochem Biophys Res Commun 1988; 156: 978-986
14. Atlante A, Passarella S, Quagliariello E, Moreno G, Salet C. Haematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: inhibition of ADP/ATP translocator. J Photochem Photobiol (B:Biology) 1989; 4: 35-46
15. Fonjo A, Palmieri F, Ritvay J, Quagliariello E. Membrane proteins in transport and phosphorylation. Azzone GF, Klingenberg ME, Quagliariello E, Siliprandi N (eds), North-Holland, Amsterdam, 1974, pp. 283-286
16. Adam H. Methods of Enzymatic analysis. Bergmeyer, HU (eds), Academic Press, New York and London, 1963, pp. 573-577
17. Addink ADF, Boer P, Wakabayashi T, Green D. Enzyme localization in beef-heart mitochondria. Eur J Biochem 1972; 29: 47-59
18. Colowick SP, Kaplan NO. Methods in Enzymology Eatabrook RW and Pullman ME (eds), 1967, 10, p. 53
19. LaNoue FK, Schoolwerth AC. Bioenergetics Ernster L (eds), Elsevier, Amsterdam-New York-Oxford, 1984, pp. 221-261
20. 5-Di(adenosine-5')pentaphosphate, a potent multisubstrate inhibitor of adenylate kinase. J Biol Chem 1973; 248: 1121-1123
21. LaNoue KF, Schoolwerth AC. Metabolite transport in mitochondria. Ann Rev Biochem 1979; 48: 871-922
22. Roberts R. Impact for molecular biology in cardiology. Am J Physiol 1991; 261 (Suppl): 8-14
23. Morgan HE, Baker KM. Cardiac hypertrophy. Mechanical, neural, and endocrine dependence. Circulation 1991; 83: 13-25
24. Frohlich ED, Apstein C, Chobanian AV, Devereux RB, Dustan HP, Dzau V, Fauad-Tarazi F, Horan MJ, Marcus M, massie B, Pfeffer MA, Re RN, Roccella EJ, Savage D, Shub C. The heart in hypertension. N Engl J Med 1992; 327: 998-1008
25. Bishop SP, Altschuld RA. Increased glycolitic metabolism in cardiac hypertrophy and congestive failure. Am J Physiol 1970; 218: 153-159
26. Opie LH. Myocardial ischemia. Metabolic pathways and implications of increased glycolysis. Cardiovasc Drugs and Therapy 1990; 4: 777-790
27. De Silva R, Camici PG. Assessment of myocardial perfusion, metabolism and pharmacology using positron emission tomography. Cardioscience 1992; 3. 205-216
28. Taegtmeyer H, Overturf ML. Effects of moderate hypertension on cardiac function and metabolim in the rabbit. Hypertension 1988; 11: 416-426
29. Lomprè A-M, Schwartz K, d'Albis A, Lacombe G, Vanthiem N, Swynghedauw B. Myosin isoenzyme distribution in chronic heart overload. Nature 1979; 282: 105-107
30. Wolf WJ, Rex KA, Geshi E, Sordahl LA. Postnatal changes in heart mitochondrial calcium and energy metabolism. Am J Physiol 1991; 261 (Heart Circ Physiol 30): H1-H8
31. Paradies G, Ruggiero FM, Dinoi P. Decreased activity of the phospate earrier and modification of lipids in cardiac mitochondria from senescent rats. Int J Biochem 1992; 24: 783-787
32. Janero DR, Burghardt B. Cardiac membrane vitamin E and malondialdehyde levels in heart muscle of normotensive and spontaneously hypertensive rats Lipid 1989, 24: 33-38
33. Ito H, Torii M, Suzuki T. A comparative study on defence systems for lipid peroxidation by free radicals in spontaneously hypertensive and normotensive rat myocardium. Comp Biochem Physiol 1992; 103B: 37-40
34. Rauch U, Schulze K, Witzenbicher B, Schulteiss HP. Alteration of the cytosolic-mitochondrial distribution of high-energy phosphate during global myocardial ischemia may contribute to early contractile failure. Circ Res 1994; 75: 760-769
35. Hassinen IE. Mitochondrial respiratory control in the myocardium. Bioch Biophys Acta 1986; 853: 135-151
36. Saks VA, Belikova YO, Kuznetsov AV. In vivo regulation of mitochondrial respiration in cardiomyocytes: specific restriction for intracellular diffusion of ADP. Biophys Acta 1991; 1074: 302-311
37. Fontanet HL, Trask RV, Haas RC, Strauss AW, Abenschein DR, Billadello JJ. Regulation of expression of M, B, and mitochondrial creatine kinase mRNAs in the left ventricle after pressure overload in rats. Circ Res 1991; 68 1007-1012
38. Pauletto P, Nascimben L, Piccolo D, Secchiero S, Vescovo G, Scannapieco G, Dalla Libera L, Carraro U, Pessina AC, Dal Palù. Ventricular myosin and creatine-kinase isoenzymes in hypertensive rats treated with captopril. Hypertension 1989; 14: 556-562
39. Smith SH, Kramer Mf, Reis I, Bishop SP, Ingwall JS. Regional changes in creatine kinase and myocyte size in hypertensive and nonhypertensive cardiac hypertrophy Circ Res 1990; 67: 1334-1344
40. Ferrari R, Cargnoni A, Bernocchi P, Gaia G, Benigno M, Pasini E, Pedersini P, Ceconi C. Effects of felodipine on the ischemic heart. insight into the mechanism of cytoprotection. Cardiovasc Drugs Ther 1996; 10: 425-437