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Volumn 25, Issue 8, 2009, Pages 843-847

Dynamics of raltegravir resistance profile in an HIV type 2-infected patient

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; DARUNAVIR PLUS RITONAVIR; INTEGRASE; RALTEGRAVIR; ZIDOVUDINE;

EID: 70349221276     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2009.0039     Document Type: Article
Times cited : (15)

References (28)
  • 1
    • 0037303182 scopus 로고    scopus 로고
    • S-1360 shionogi-glaxo smith kline
    • Billich A: S-1360 Shionogi-GlaxoSmithKline. Curr Opin Investig Drugs 2003;4(2):206-209.
    • (2003) Curr Opin Investig Drugs , vol.4 , Issue.2 , pp. 206-209
    • Billich, A.1
  • 2
    • 0034723439 scopus 로고    scopus 로고
    • Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
    • Hazuda DJ, Felock P, Witmer M, et al.: Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells. Science 2000;287(5453):646-650.
    • (2000) Science , vol.287 , Issue.5453 , pp. 646-650
    • Hazuda, D.J.1    Felock, P.2    Witmer, M.3
  • 3
    • 3843108916 scopus 로고    scopus 로고
    • A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase
    • Hazuda DJ, Anthony NJ, Gomez RP, et al.: A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase. Proc Natl Acad Sci USA 2004;101(31):11233-11238.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.31 , pp. 11233-11238
    • Hazuda, D.J.1    Anthony, N.J.2    Gomez, R.P.3
  • 4
    • 33644863638 scopus 로고    scopus 로고
    • Novel HIV-1 integrase inhibitors derived from quinolone antibiotics
    • Sato M, Motomura T, Aramaki H, et al.: Novel HIV-1 integrase inhibitors derived from quinolone antibiotics. J Med Chem 2006;49(5):1506-1508.
    • (2006) J Med Chem , vol.49 , Issue.5 , pp. 1506-1508
    • Sato, M.1    Motomura, T.2    Aramaki, H.3
  • 5
    • 33748113778 scopus 로고    scopus 로고
    • Antiviral activity, pharmacokinetics, and dose response of the HIV-1 integrase inhibitor GS-9137 ( JTK-303) in treatment-naive and treatment-experienced patients
    • DeJesus E, Berger D, Markowitz M, et al.: Antiviral activity, pharmacokinetics, and dose response of the HIV-1 integrase inhibitor GS-9137 ( JTK-303) in treatment-naive and treatment-experienced patients. J Acquir Immune Defic Syndr 2006;43(1):1-5.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , Issue.1 , pp. 1-5
    • De Jesus, E.1    Berger, D.2    Markowitz, M.3
  • 6
    • 34147136222 scopus 로고    scopus 로고
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial
    • Grinsztejn B, Nguyen BY, Katlama C, et al.: Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial. Lancet 2007; 369(9569):1261-1269.
    • (2007) Lancet , vol.369 , Issue.9569 , pp. 1261-1269
    • Grinsztejn, B.1    Nguyen, B.Y.2    Katlama, C.3
  • 7
    • 44449096529 scopus 로고    scopus 로고
    • Raltegravir treatment response in an HIV-2 infected patient: A case report
    • Garrett N, Xu L, Smit E, et al.: Raltegravir treatment response in an HIV-2 infected patient: A case report. AIDS 2008;22(9): 1091-1092.
    • (2008) AIDS , vol.22 , Issue.9 , pp. 1091-1092
    • Garrett, N.1    Xu, L.2    Smit, E.3
  • 8
    • 43149114678 scopus 로고    scopus 로고
    • Virological and immunological response to HAART regimen containing integrase inhibitors in HIV-2-infected patients
    • Damond F, Lariven S, Roquebert B, et al.: Virological and immunological response to HAART regimen containing integrase inhibitors in HIV-2-infected patients. AIDS 2008; 22(5):665-666.
    • (2008) AIDS , vol.22 , Issue.5 , pp. 665-666
    • Damond, F.1    Lariven, S.2    Roquebert, B.3
  • 9
    • 37249065868 scopus 로고    scopus 로고
    • Resistance to the HIV-integrase inhibitor raltegravir: Analysis of protocol 005, a Phase II study in patients with triple-class resistant HIV-1 infection
    • Abstract 8
    • Hazuda DJ, Miller MD, Nguyen BY, et al.: Resistance to the HIV-integrase inhibitor raltegravir: Analysis of protocol 005, a Phase II study in patients with triple-class resistant HIV-1 infection. Antiviral Ther 2007;12:S10 (Abstract 8).
    • (2007) Antiviral Ther , vol.12
    • Hazuda, D.J.1    Miller, M.D.2    Nguyen, B.Y.3
  • 10
    • 47949114939 scopus 로고    scopus 로고
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection
    • Cooper DA, Steigbigel RT, Gatell JM, et al.: Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. N Engl J Med 2008;359(4):355-365.
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 355-365
    • Cooper, D.A.1    Steigbigel, R.T.2    Gatell, J.M.3
  • 11
    • 54049102468 scopus 로고    scopus 로고
    • Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy
    • Charpentier C, Karmochkine M, Laureillard D, et al.: Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy. HIV Med 2008;9(9): 765-770.
    • (2008) HIV Med , vol.9 , Issue.9 , pp. 765-770
    • Charpentier, C.1    Karmochkine, M.2    Laureillard, D.3
  • 12
    • 42049119625 scopus 로고    scopus 로고
    • Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro
    • Malet I, Delelis O, Valantin MA, et al.: Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro. Antimicrob Agents Chemother 2008;52(4):1351-1358.
    • (2008) Antimicrob Agents Chemother , vol.52 , Issue.4 , pp. 1351-1358
    • Malet, I.1    Delelis, O.2    Valantin, M.A.3
  • 13
    • 40549125135 scopus 로고    scopus 로고
    • Resistance and cross-resistance to first generation integrase inhibitors: Insights from a phase II study of elvitegravir (GS-9137
    • Abstract 9
    • McColl DJ, Fransen S, Gupta S, et al.: Resistance and cross-resistance to first generation integrase inhibitors: Insights from a phase II study of elvitegravir (GS-9137). Antiviral Ther 2007;12:S11 (Abstract 9).
    • (2007) Antiviral Ther , vol.12
    • McColl, D.J.1    Fransen, S.2    Gupta, S.3
  • 14
    • 55249105017 scopus 로고    scopus 로고
    • Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors
    • Goethals O, Clayton R, Van GM, et al.: Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors. J Virol 2008;82(21):10366-10374.
    • (2008) J Virol , vol.82 , Issue.21 , pp. 10366-10374
    • Goethals, O.1    Clayton, R.2    Van, G.M.3
  • 15
    • 0037119027 scopus 로고    scopus 로고
    • Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients
    • Xu L, Hue S, Taylor S, et al.: Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients. AIDS 2002;16(12):1684-1686.
    • (2002) AIDS , vol.16 , Issue.12 , pp. 1684-1686
    • Xu, L.1    Hue, S.2    Taylor, S.3
  • 16
    • 48749125376 scopus 로고    scopus 로고
    • Genetic diversity of integrase (IN) sequences in antiretroviral treatment-naive and treatment-experienced HIV type 2 patients
    • Xu L, Anderson J, Ferns B, et al.: Genetic diversity of integrase (IN) sequences in antiretroviral treatment-naive and treatment-experienced HIV type 2 patients. AIDS Res Hum Retroviruses 2008;24(7):1003-1007.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , Issue.7 , pp. 1003-1007
    • Xu, L.1    Anderson, J.2    Ferns, B.3
  • 17
    • 0033840455 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy
    • Bacheler LT, Anton ED, Kudish P, et al.: Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy. Antimicrob Agents Chemother 2000;44(9):2475-2484.
    • (2000) Antimicrob Agents Chemother , vol.44 , Issue.9 , pp. 2475-2484
    • Bacheler, L.T.1    Anton, E.D.2    Kudish, P.3
  • 18
    • 54549099338 scopus 로고    scopus 로고
    • HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro
    • Roquebert B, Damond F, Collin G, et al.: HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro. J Antimicrob Chemother 2008;62(5): 914-920.
    • (2008) J Antimicrob Chemother , vol.62 , Issue.5 , pp. 914-920
    • Roquebert, B.1    Damond, F.2    Collin, G.3
  • 19
    • 52749086245 scopus 로고    scopus 로고
    • Natural variation of HIV-1 group M integrase: Implications for a new class of antiretroviral inhibitors
    • Rhee SY, Liu TF, Kiuchi M, et al.: Natural variation of HIV-1 group M integrase: Implications for a new class of antiretroviral inhibitors. Retrovirology 2008;5:74.
    • (2008) Retrovirology , vol.5 , pp. 74
    • Rhee, S.Y.1    Liu, T.F.2    Kiuchi, M.3
  • 21
    • 7744240084 scopus 로고    scopus 로고
    • Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360
    • Fikkert V, Hombrouck A, Van RB, et al.: Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360. AIDS 2004;18(15): 2019-2028.
    • (2004) AIDS , vol.18 , Issue.15 , pp. 2019-2028
    • Fikkert, V.1    Hombrouck, A.2    Van, R.B.3
  • 22
    • 50949119501 scopus 로고    scopus 로고
    • Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance
    • Zahm JA, Bera S, Pandey KK, et al.: Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance. Antimicrob Agents Chemother 2008;52(9):3358-3368.
    • (2008) Antimicrob Agents Chemother , vol.52 , Issue.9 , pp. 3358-3368
    • Zahm, J.A.1    Bera, S.2    Pandey, K.K.3
  • 23
    • 51549116289 scopus 로고    scopus 로고
    • Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants
    • Marinello J, Marchand C, Mott BT, et al.: Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants. Biochemistry 2008;47(36):9345-9354.
    • (2008) Biochemistry , vol.47 , Issue.36 , pp. 9345-9354
    • Marinello, J.1    Marchand, C.2    Mott, B.T.3
  • 24
    • 44449155764 scopus 로고    scopus 로고
    • Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137
    • Hombrouck A, Voet A, Van RB, et al.: Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137. Antimicrob Agents Chemother 2008;52(6):2069-2078.
    • (2008) Antimicrob Agents Chemother , vol.52 , Issue.6 , pp. 2069-2078
    • Hombrouck, A.1    Voet, A.2    Van, R.B.3
  • 25
    • 53549113615 scopus 로고    scopus 로고
    • Selection of the Q148R integrase inhibitor resistance mutation in a failing raltegravir containing regimen
    • Roquebert B, Blum L, Collin G, et al.: Selection of the Q148R integrase inhibitor resistance mutation in a failing raltegravir containing regimen. AIDS 2008;22(15):2045-2046.
    • (2008) AIDS , vol.22 , Issue.15 , pp. 2045-2046
    • Roquebert, B.1    Blum, L.2    Collin, G.3
  • 26
    • 37849002059 scopus 로고    scopus 로고
    • Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir ( JTK-303=GS-9137)
    • Shimura K, Kodama E, Sakagami Y, et al.: Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir ( JTK-303=GS-9137). J Virol 2008;82(2):764-774.
    • (2008) J Virol , vol.82 , Issue.2 , pp. 764-774
    • Shimura, K.1    Kodama, E.2    Sakagami, Y.3
  • 27
    • 11844257530 scopus 로고    scopus 로고
    • Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine
    • Lecossier D, Shulman NS, Morand-Joubert L, et al.: Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. J Acquir Immune Defic Syndr 2005;38(1):37-42.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , Issue.1 , pp. 37-42
    • Lecossier, D.1    Shulman, N.S.2    Morand-Joubert, L.3
  • 28
    • 1842484005 scopus 로고    scopus 로고
    • Role of minority populations of human immunodeficiency virus type 1 in the evolution of viral resistance to protease inhibitors
    • Charpentier C, Dwyer DE, Mammano F, et al.: Role of minority populations of human immunodeficiency virus type 1 in the evolution of viral resistance to protease inhibitors. J Virol 2004;78(8):4234-4247.
    • (2004) J Virol , vol.78 , Issue.8 , pp. 4234-4247
    • Charpentier, C.1    Dwyer, D.E.2    Mammano, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.