메뉴 건너뛰기




Volumn 9, Issue 9, 2008, Pages 765-770

Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy

Author keywords

HIV; Integrase; Raltegravir; Resistance

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; DARUNAVIR PLUS RITONAVIR; EMTRICITABINE; ENFUVIRTIDE; ETRAVIRINE; INTEGRASE; INTEGRASE INHIBITOR; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; RALTEGRAVIR; TENOFOVIR; UNCLASSIFIED DRUG; VIRUS DNA; ZIDOVUDINE;

EID: 54049102468     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2008.00628.x     Document Type: Article
Times cited : (90)

References (18)
  • 1
  • 2
    • 34248177765 scopus 로고    scopus 로고
    • Results of BENCHMRK-1, a phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus
    • for the BENCHMRK-1 Study Group. Los Angeles, USA, February [Abstract 105aLB]
    • Cooper D, Gatell J, Rockstroh J et al. for the BENCHMRK-1 Study Group. Results of BENCHMRK-1, a phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus. 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, USA, February 2007 [Abstract 105aLB].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Cooper, D.1    Gatell, J.2    Rockstroh, J.3
  • 3
    • 34248205567 scopus 로고    scopus 로고
    • Results of BENCHMRK-2, a phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus
    • for the BENCHMRK-2 Study Group. Los Angeles, USA, February [Abstract 105bLB]
    • Steigbigel R, Kumar P, Eron J et al. for the BENCHMRK-2 Study Group. Results of BENCHMRK-2, a phase III study evaluating the efficacy and safety of MK-0518, a novel HIV-1 integrase inhibitor, in patients with triple-class resistant virus. 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, USA, February 2007 [Abstract 105bLB].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Steigbigel, R.1    Kumar, P.2    Eron, J.3
  • 4
    • 34147136222 scopus 로고    scopus 로고
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial
    • Grinsztejn B, Nguyen BY, Katlama C et al. Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial. Lancet 2007; 369: 1261-1269.
    • (2007) Lancet , vol.369 , pp. 1261-1269
    • Grinsztejn, B.1    Nguyen, B.Y.2    Katlama, C.3
  • 5
    • 34748860363 scopus 로고    scopus 로고
    • Rapid and durable antiretroviral effect of the HIV-1 integrase inhibitor raltegravir as part of combination therapy in treatment-naïve patients with HIV-1 infection: Results of a 48-week controlled study
    • Markowitz M, Nguyen BY, Gotuzzo E et al. Rapid and durable antiretroviral effect of the HIV-1 integrase inhibitor raltegravir as part of combination therapy in treatment-naïve patients with HIV-1 infection: Results of a 48-week controlled study. J Acquir Immune Defic Syndr 2007; 46: 125-133.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 125-133
    • Markowitz, M.1    Nguyen, B.Y.2    Gotuzzo, E.3
  • 6
    • 10744226580 scopus 로고    scopus 로고
    • Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations
    • Fikkert V, Van Maele B, Vercammen J et al. Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations. J Virol 2003; 77: 11459-11470.
    • (2003) J Virol , vol.77 , pp. 11459-11470
    • Fikkert, V.1    Van Maele, B.2    Vercammen, J.3
  • 7
    • 3843108916 scopus 로고    scopus 로고
    • A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase
    • Hazuda DJ, Anthony NJ, Gomez RP et al. A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase. Proc Natl Acad Sci USA 2004; 101: 11233-11238.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11233-11238
    • Hazuda, D.J.1    Anthony, N.J.2    Gomez, R.P.3
  • 8
    • 34248203565 scopus 로고    scopus 로고
    • Resistance profile of HIV-1 mutants in vitro selected by the HIV-1 integrase inhibitor, GS-9137 (JTK-303)
    • Los. Angeles, USA, February [Abstract 627]
    • Jones G, Ledford R, Yu F et al. Resistance profile of HIV-1 mutants in vitro selected by the HIV-1 integrase inhibitor, GS-9137 (JTK-303). 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, USA, February 2007 [Abstract 627].
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Jones, G.1    Ledford, R.2    Yu, F.3
  • 9
    • 35648950291 scopus 로고    scopus 로고
    • Resistance to the HIV-integrase inhibitor raltegravir: Analysis of protocol 005, a phase 2 study in patients with triple-class resistant HIV-1 infection
    • Barbados, West Indies, June [Abstract 8]
    • Hazuda DJ, Miller MD, Nguyen BY, Zhao J. Resistance to the HIV-integrase inhibitor raltegravir: Analysis of protocol 005, a phase 2 study in patients with triple-class resistant HIV-1 infection. XVI International HIV Drug Resistance Workshop. Barbados, West Indies, June 2007 [Abstract 8].
    • (2007) XVI International HIV Drug Resistance Workshop
    • Hazuda, D.J.1    Miller, M.D.2    Nguyen, B.Y.3    Zhao, J.4
  • 10
    • 35648940077 scopus 로고    scopus 로고
    • Resistance and cross-resistance to first generation integrase inhibitors: Insights from a phase 2 study of elvitegravir (GS-9137)
    • Barbados, West Indies, June [Abstract 9]
    • McColl DJ, Fransen S, Gupta S et al. Resistance and cross-resistance to first generation integrase inhibitors: Insights from a phase 2 study of elvitegravir (GS-9137). XVI International HIV Drug Resistance Workshop. Barbados, West Indies, June 2007 [Abstract 9].
    • (2007) XVI International HIV Drug Resistance Workshop
    • McColl, D.J.1    Fransen, S.2    Gupta, S.3
  • 11
    • 37549021644 scopus 로고    scopus 로고
    • Biochemical characterizations and drug sensitivity of the effect of mutations selected in HIV-1 integrase gene associated with failure to raltegravir (MK-0518)
    • Barbados, West Indies, June [Abstract 7]
    • Malet I, Delelis O, Valantin MA et al. Biochemical characterizations and drug sensitivity of the effect of mutations selected in HIV-1 integrase gene associated with failure to raltegravir (MK-0518). XVI International HIV Drug Resistance Workshop. Barbados, West Indies, June 2007 [Abstract 7].
    • (2007) XVI International HIV Drug Resistance Workshop
    • Malet, I.1    Delelis, O.2    Valantin, M.A.3
  • 12
    • 5644220295 scopus 로고    scopus 로고
    • Potential drug resistance polymorphisms in the integrase gene of HIV type 1 subtype A
    • Herring BL, Cunningham AL, Dwyer DE. Potential drug resistance polymorphisms in the integrase gene of HIV type 1 subtype A. AIDS Res Hum Retroviruses 2004; 20: 1010-1014.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 1010-1014
    • Herring, B.L.1    Cunningham, A.L.2    Dwyer, D.E.3
  • 13
    • 42549140294 scopus 로고    scopus 로고
    • Impact of baseline NNRTI mutations on the virological response to TMC125 in the Phase III clinical trials DUET-1 and DUET-2
    • Barbados, West Indies, June [Abstract 32]
    • Vingerhoets J, Buelens A, Peeters M et al. Impact of baseline NNRTI mutations on the virological response to TMC125 in the Phase III clinical trials DUET-1 and DUET-2. XVI International HIV Drug Resistance Workshop. Barbados, West Indies, June 2007 [Abstract 32].
    • (2007) XVI International HIV Drug Resistance Workshop
    • Vingerhoets, J.1    Buelens, A.2    Peeters, M.3
  • 14
    • 34447263572 scopus 로고    scopus 로고
    • Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance
    • Lataillade M, Chiarella J, Kozal MJ. Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance. Antivir Ther 2007; 12: 563-570.
    • (2007) Antivir Ther , vol.12 , pp. 563-570
    • Lataillade, M.1    Chiarella, J.2    Kozal, M.J.3
  • 16
    • 0027968068 scopus 로고
    • Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ. Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22: 4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 17
    • 0024307824 scopus 로고
    • Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea
    • Kishino H, Hasegawa M. Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea. J Mol Evol 1989; 29: 170-179.
    • (1989) J Mol Evol , vol.29 , pp. 170-179
    • Kishino, H.1    Hasegawa, M.2
  • 18
    • 0030203863 scopus 로고    scopus 로고
    • TreeView: An application to display phylogenetic trees on personal computers
    • Page RD. TreeView: An application to display phylogenetic trees on personal computers. Comput Appl Biosci 1996; 12: 357-358.
    • (1996) Comput Appl Biosci , vol.12 , pp. 357-358
    • Page, R.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.