Mercury induces regional and cell-specific stress protein expression in rat kidney

Toxicological Sciences

Volumn 53, Issue 2, 2000, Pages 447-457

  Goering, Peter L ^a,d   Fisher, Benjamin R ^a,c   Noren, Bradley T ^b   Papaconstantinou, Andriana ^a   Rojko, Jennifer L ^b   Marler, Ronald J ^c  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

^c UK   (United States)

^d CENTER FOR DEVICES AND RADIOLOGICAL HEALTH   (United States)

Author keywords

Acute renal injury; Glucose regulated proteins; Grp94; Heat shock proteins; Hsp72; Immunohistochemistry; Kidney; Mercury; Stress proteins

Indexed keywords

GLUCOSE REGULATED PROTEIN; HEAT SHOCK PROTEIN; MERCURY; MERCURY CHLORIDE; MONOCLONAL ANTIBODY;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; NEPHROTOXICITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; RAT;

EID: 0033966551     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/53.2.447     Document Type: Article

References (62)

1. Aoki, Y., Lipsky, M. M., and Fowler, B. A. (1990). Alteration in protein synthesis in primary cultures of rat kidney proximal tubule epithelial cells by exposure to gallium, indium, and arsenite. Toxicol. Appl. Pharmacol. 106, 462-468.
2. Arrigo, A. P., Suhan, J. P., and Welch, W. J. (1988). Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat-shock protein. Mol. Cell Biol. 8, 5059-5071.
3. Bardella, L., and Comolli, R. (1994). Differential expression of c-jun, c-fos, and hsp70 mRNAs after folic acid and ischemia-reperfusion injury: Effect of antioxidant treatment. Exp. Nephrol. 2, 158-165.
4. Beckmann, R. P., Mizzen, L. A., and Welch, W. J. (1990). Interaction of hsp70 with newly synthesized proteins: Implications for protein folding and assembly. Science 248, 850-854.
5. Beckmann, R. P., Lovett, M., and Welch, W. J. (1992). Examining the function and regulation of hsp70 in cells subjected to metabolic stress. J. Cell Biol. 117, 1137-1150.
6. Borkan, S. C., Emami, C. A., and Schwartz, J. H. (1993). Heat stress protein-associated cytoprotection of inner medullary collecting duct cells from rat kidney. Am. J. Physiol. 265, F333-341.
7. Brown, C. R., Martin, R. L., Hansen, W. J., Beckmann, R. P., and Welch, W. J. (1993). The constitutive and stress-inducible forms of hsp70 exhibit functional similarities and interact with one another in an ATP-dependent fashion. J. Cell Biol. 120, 1101-1112.
8. Buckiová, D., and Jelínek, R. (1995). Heat-shock proteins and teratogenesis. Reprod. Toxicol. 9, 501-511.
9. Chatson, G., Perdrizet, G., Anderson, C., Pleau, M., Berman, M., and Schweizer, R. (1990). Heat shock protects kidneys against warm ischemic injury. Curr. Surg. Nov-Dec, 420-423.
10. Chiang, H. L., Terlecky, S. R., Plant, C. P., and Dice, J. F. (1989). A role for a 70-kilodalton heat-shock protein in lysosomal degradation of intracellular proteins. Science 246, 382-385.
11. Coimbra, T. M., Cieslinski, D. A., and Humes, H. D. (1990). Epidermal growth factor accelerates renal repair in mercuric chloride nephrotoxicity. Am. J. Physiol. 259, F438-443.
12. Cowley, Jr., B. D., and Gudapaty, S. (1995). Temporal alterations in regional gene expression after nephrotoxic renal injury. J. Lab. Clin. Med. 125, 187-199.
13. Craig, E. A., Baxter, B. K., Becker, J., Halladay, J., and Ziegelhoffer, T. (1994). Cytosolic hsp70s of Saccharomyces cerevisiae: Roles in protein synthesis, protein translocation, proteolysis, and regulation. In The Biology of Heat-Shock Proteins and Molecular Chaperones (R. I. Morimoto, A. Tissieres, and C. Georgopoulos, Eds.), pp. 31-53. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
14. Ellis, R. J. (1989). The molecular chaperone concept. (Review) Semin. Cell Biol. 1, 1-9.
15. Emami, A., Schwartz, J., and Borkan, S. (1991). Transient ischemia or heat-shock stress induces a cytoprotective protein in rat kidney. Am. J. Physiol. 262, F479-486.
16. Fisher, B. R., Heredia, D. J., and Brown, K. (1995). Induction of hsp72 in heat-treated rat embryos: A tissue-specific response. Teratology 52, 90-100.
17. Fukuda, A., Osawa, T., Oda, H., Tanaka, T., Toyokuni, S., and Uchida, K. (1996). Oxidative stress response in iron-induced acute nephrotoxicity: Enhanced expression of heat-shock protein 90. Biochem. Biophys. Res. Commun. 219, 76-81.
18. Gething, M. J., and Sambrook, J. (1992). Protein folding in the cell. Nature 355, 33-45.
19. Goering, P. L., and Fisher, B. R. (1995). Metals and stress proteins. In Handbook of Experimental Pharmacology, Vol. 115: Toxicology of Metals - Biochemical Aspects (R. A. Goyer and M. G. Cherian, Eds.), pp. 229-266. Springer Verlag, New York.
20. Goering, P. L., Fisher, B. R., Chaudhary, P. P., and Dick, C. A. (1992). Relationship between stress protein induction in rat kidney by mercuric chloride and nephrotoxicity. Toxicol. Appl. Pharmacol. 113, 184-191.
21. Goering, P. L., Fisher, B. R., and Kish, C. L. (1993a). Stress protein synthesis induced in rat liver by cadmium precedes hepatotoxicity. Toxicol. Appl. Pharmacol. 122, 139-148.
22. Goering, P. L., Kish, C. L., and Fisher, B. R. (1993b). Stress protein synthesis induced by cadmium-cysteine in rat kidney. Toxicol. 85, 25-39.
23. Gritzka, T. L., and Trump, B. F. (1968). Renal tubular lesions caused by mercuric chloride. Am. J. Pathol. 52, 1225-1227.
24. Hansen, D. K., Anson, J. F., Hinson, W. G., and Pipkin, J. L., Jr. (1988). Phenytoin-induced stress protein synthesis in mouse embryonic tissue. Proc. Soc. Exp. Biol. Med. 189, 136-140.
25. Hernádez-Pando, R., Pedraza-Chaverri, J., Orozco-Estévez, H., Silva-Serna, P., Moreno, I., Rondán-Zárate, A., Elinos, M., Correa-Rotter, R., and Larriva-Sahd, J. (1995). Histological and subcellular distribution of 65 and 70 kDa heat-shock proteins in experimental nephrotoxic injury. Exp. Toxic Pathol. 47, 501-508.
26. Hightower, L. E. (1991). Heat shock, stress proteins, chaperones, and proteotoxicity. Cell 66, 191-197.
27. Hightower, L. E., Sadis, S. E., and Takenaka, I. M. (1994). Interaction of vertebrate hsc70 and hsp70 with unfolded proteins and peptides. In The Biology of Heat-shock Proteins and Molecular Chaperones (R. I. Morimoto, A. Tissieres, and C. Georgopoulos, Eds.), pp. 179-209. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
28. Howard, K. J., Holley, S. J., Yamamoto, K. R., and Distelhorst, C. W. (1990). Mapping the HSP90 binding region of the glucocorticoid receptor. J. Biol. Chem. 265, 11928-11935.
29. Johnston, R. N., and Kucey, B. L. (1988). Competitive inhibition of hsp70 gene expression causes thermosensitivity. Science 242, 1551-1554.
30. Kimmel, G. L., Cuff, J. M., Kimmel, C. A., Heredia, D. J., Tudor, N., and Silverman, P. M. (1993). Embryonic development in vitro, following short-duration exposure to heat. Teratology 47, 243-251.
31. Lindquist, S. (1986). The heat-shock response. Ann. Rev. Biochem. 55, 1151-1191.
32. Lovis, C., Mach, F., Donati, Y. R. A., Bonventre, J. V., and Polla, B. S. (1994). Heat shock proteins and the kidney. Renal Failure 16, 179-192.
33. Mirkes, P. E. (1985). Effects of acute exposure to elevated temperatures on rat embryo growth and development in vitro. Teratology 32, 259-266.
34. Mirkes, P. E. (1987). Hyperthermia-induced heat-shock response and thermotolerance in postimplantation rat embryos. Dev. Biol. 119, 115-122.
35. Morimoto, R. I., Tissieres, A., and Georgopoulos, C. (1990). The stress response, function of the proteins, and perspectives. In Stress Proteins in Biology and Medicine (R. I. Morimoto, A. Tissieres, and C. Georgopoulos, Eds.), pp. 1-36. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
36. 1 mice. Technical Report No. 408, pp. 36-65. U.S. Dept. of Hlth. Human Services, Natl. Inst. Hlth., Res. Tri. Pk., NC.
37. Nissim, I., Hardy, M., Pleasure, J., Nissim, I., and States, B. (1992). A mechanism of glycine and alanine cytoprotective action: Stimulation of stress-induced HSP-70 mRNA. Kidney Intl. 42, 775-782.
38. Nover, L. (1991). Heat Shock Response. CRC Press, Boca Raton, FL.
39. Nowak, T. S., Jr. (1993). Synthesis of heat-shock/stress proteins during cellular injury. Ann. N Y Acad. Sci. 679, 142-156.
40. Perdrizet, G. A., Kaneko, H., Buckley, T. M., Fishman, M. S., Pleau, M., Bow, L., and Schweizer, R. T. (1993). Heat shock and recovery protects renal allografts from warm ischemic injury and enhances hsp72 production. Transplantation Proc. 25, 1670-1673.
41. Plumier, J. C., Krueger, A. M., Currie, R. W., Kontoyiannis, D., Kollias, G., and Pagoulatos, G. N. (1997). Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury. Cell Stress Chaperones 2, 162-167.
42. Plumier, J. C., Ross, B. M., Currie, R. W., Angelidis, C. E., Kazlaris, H., Kollias, G., and Pagoulatos, G. N. (1995). Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. J. Clin. Invest. 95, 1854-1860.
43. Riabowol, K. T., Mizzen, L. A., and Welch, W. J. (1988). Heat shock is lethal to libroblasts microinjected with antibodies against hsp70. Science 242, 433-436.
44. Ritossa, F. M. (1962). A new puffing pattern induced by heat shock and DNP in Drosophila. Experimentia 18, 571-573.
45. Rothman, J. E. (1989). Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells. Cell 59, 591-601.
46. Salminen, W. F., Jr., Roberts, S. M., Fenna, M., and Voellmy, R. (1997). Heat-shock protein induction in murine liver after acute treatment with cocaine. Hepatology 25, 1147-1153.
47. Salminen, W. F., Jr., Voellmy, R., and Roberts, S. M. (1997). Effect of N-acetylcysteine on heat-shock-protein induction by acetaminophen in mouse liver. J. Pharmacol. Exp. Ther. 286, 519-524.
48. Sanchez, Y., and Lindquist, S. L. (1990). HSP104 required for induced thermotolerance. Science 248, 1112-1115.
49. Sanders, B. M., Goering, P. L., and Jenkins, K. (1996). The role of general and metal-specific cellular responses in protection and repair of metal-induced damage: Stress proteins and metallothioneins. In Toxicology of Metals (L. W. Chang, Ed.), pp. 165-187. CRC/Lewis Publishers, New York.
50. Satoh, K., Wakui, H., Komatsuda, A., Nakamoto, Y., Miura, A. B., Itoh, H., and Tashima, Y. (1994). Induction and altered localization of 90-kDa heat-shock protein in rat kidneys with cisplatin-induced acute renal failure. Ren. Fail. 16, 313-323.
51. Schlesinger, M. J. (1990). Heat shock proteins. J. Biol. Chem. 265, 12111-12114.
52. Schlesinger, M. J. (1994). How the cell copes with stress and the function of proteins. Pediatric Res. 36, 1-6.
53. Shelton, K. R., Todd, J. M., and Egle, P. M. (1986). The induction of stress-related proteins by lead. J. Biol. Chem. 261, 1935-1940.
54. Tytell, M., Barbe, M. F., and Brown, I. R. (1994). Induction of heat-shock (stress) protein 70 and its mRNA in the normal and light-damaged rat retina after whole body hyperthermia. J. Neurosci. Res. 38, 19-31.
55. Van Why, S. K., Hildebrandt, F., Ardito, T., Mann, A. S., Siegel, N. J., and Kashgarian, M. (1992). Induction and intracellular localization of HSP-72 after renal ischemia. Am. J. Physiol. 263, F769-F775.
56. Van Why, S. K., Mann, A. S., Thulin, G., Zhu, X.-H., Kashgarian, M., and Siegel, N. J. (1994). Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat. J. Clin. Invest. 94, 1518-1523.
57. Walsh, D. A., Li, K., Speirs, J., Crowther, C. E., and Edwards, M. J. (1989). Regulation of the inducible heat-shock 71 genes in early neural development of cultured rat embryos. Teratology 40, 321-334.
58. Welch, W. J. (1992). Mammalian stress response: Cell physiology, structure/ function of stress proteins, and implications for medicine and disease. Physiol. Rev. 72, 1063-1081.
59. Welch, W. J. (1993). How cells respond to stress. Sci. Am. 268, 56-64.
60. Welch, W. J., and Feramisco, J. R. (1985). Disruption of the three cytoskeletal networks in mammalian cells does not affect transcription, translation, or protein translocation changes induced by heat shock. Mol. Cell Biol. 5, 1571-1581.
61. Welch, W. J., and Mizzen, L. A. (1988). Characterization of the thermotolerant cell: II. Effects on the intercellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes. J. Cell Biol. 106, 1117-1130.
62. Yamamoto N., Maki, A., Swann, J. D., Berezesky, I. K., and Trump, B. F. (1993). Induction of immediate early and stress genes in rat proximal tubule epithelium following injury: The significance of cytosolic ionized calcium. Ren. Fail. 15, 163-171.