The biological chemistry of lead

Current Opinion in Chemical Biology

Volumn 5, Issue 2, 2001, Pages 223-227

  Godwin, Hilary Arnold ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LEAD; PEPTIDE; PORPHOBILINOGEN SYNTHASE; RECOMBINANT PROTEIN; SYNAPTOTAGMIN; ZINC;

BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; BIOAVAILABILITY; ENZYME ANALYSIS; HUMAN; LEAD POISONING; METAL BINDING; NONHUMAN; PROTEIN BINDING; PROTEIN TARGETING; REVIEW;

EID: 0035313109     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00194-0     Document Type: Review

References (47)

1. Lead in the inner cities
2. The paradox of lead poisoning and prevention
3. Childhood lead poisoning: The promise and abandonment of primary prevention
4. Finger-loops, oncogenes, and metals
5. Evidence that lead acts as a calcium substitute in second messenger metabolism
6. Lead-calcium interactions in cellular lead toxicity
7. Lead poisoning, haem synthesis and 5-aminolaevulinic acid dehydratase
8. Molecular mechanisms of lead neurotoxicity
9. 2+
10. A highly sensitive and selective catalytic DNA biosensor for lead ions
11. Lead
12. Picomolar concentrations of lead stimulate brain protein kinase C
13. Measurement of intracellular free zinc in living cortical neurons: Routes of entry
14. Transition-metal storage, transport, and biomineralization
15. Characteristics of lead adaption in a rat kidney cell line. I. Uptake and subcellular and subnuclear distribution of lead
16. Lead and δ-aminolevulinic acid dehydratase levels in mentally retarded children and in lead-poisoned suckling rats
17. 2+
18. X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase
19. The molecular mechanism of lead inhibition of human porphobilinogen synthase
20. 4]
21. Interactions of metal ions with the sulfhydryl group of serum albumin
22. Chain length-dependent Pb(II)-coordination in phytochelatins
23. Lead fingers: Pb(II) binding to structural zinc-binding domains determined directly by monitoring lead-thiolate charge-transfer bands
24. Lead interaction with human protamine (HP2) as a mechanism of male reproductive toxicity
25. Lone pair functionality in divalent lead compounds
26. Lead inhibition of DNA-binding mechanism of Cys(2)His(2) zinc finger proteins
27. Immediate early gene expression in PC12 cells exposed to lead: Requirement for protein kinase C
28. Low-level lead-induced neurotoxicity in children: An update on central nervous system effects
29. Presynaptic and postsynaptic effects of lead at the frog neuromuscular junction
30. 2+ in calmodulin
31. Protein kinase C: Structure, function, and regulation
32. 2+-binding domain
33. 2+/phospholipid-binding fold
34. Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction
35. Synaptotagmin is a molecular target for lead
36. Exploring the new world of the genome with DNA microarrays
37. Proteomics to study genes and genomics
38. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
39. Cloning and characterization of a mammalian proton-coupled metal-ion transporter
40. Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells
41. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
42. Pb(II)-translocating P-type ATPases
43. The ATP hydrolytic activity of purified ZntA, a Pb(II)/Cd(II)/Zn(II)-translocating ATPase from Escherichia coli
44. 2+ with high selectivity
45. Cadmium and lead interactions with transcription factor IIIA from Xenopus laevis: A model for zinc finger protein reactions with toxic metal ions and metallothionein