Taking microRNAs to heart

Trends in Molecular Medicine

Volumn 14, Issue 6, 2008, Pages 254-260

  Callis, Thomas E ^a   Wang, Da Zhi ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MICRORNA;

CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CORONARY ARTERY DISEASE; GENE EXPRESSION REGULATION; HEART ARRHYTHMIA; HEART CONDUCTION; HEART DEVELOPMENT; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; NONHUMAN; REVIEW; RNA TRANSLATION;

ANIMALS; CARDIOMEGALY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HEART; HUMANS; MICRORNAS;

MURINAE;

EID: 44649106334     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2008.03.006     Document Type: Review

References (54)

1. Kiriakidou M., et al. An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell 129 (2007) 1141-1151
2. Bagga S., et al. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122 (2005) 553-563
3. Humphreys D.T., et al. MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 16961-16966
4. Vasudevan S., et al. Switching from repression to activation: microRNAs can up-regulate translation. Science 318 (2007) 1931-1934
5. Lewis B.P., et al. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120 (2005) 15-20
6. Olson E.N. A decade of discoveries in cardiac biology. Nat. Med. 10 (2004) 467-474
7. Olson E.N. Gene regulatory networks in the evolution and development of the heart. Science 313 (2006) 1922-1927
8. Chen J.F., et al. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 2111-2116
9. Zhao Y., et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129 (2007) 303-317
10. Thum T., et al. MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 116 (2007) 258-267
11. van Rooij E., et al. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 18255-18260
12. Zhao Y., et al. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436 (2005) 214-220
13. + channel expression contributing to QT prolongation in diabetic hearts. J. Biol. Chem. 282 (2007) 12363-12367
14. Yang B., et al. The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat. Med. 13 (2007) 486-491
15. Care A., et al. MicroRNA-133 controls cardiac hypertrophy. Nat. Med. 13 (2007) 613-618
16. van Rooij E., et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316 (2007) 575-579
17. Bernstein E., et al. Dicer is essential for mouse development. Nat. Genet. 35 (2003) 215-217
18. Wienholds E., et al. The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat. Genet. 35 (2003) 217-218
19. Giraldez A.J., et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308 (2005) 833-838
20. Andl T., et al. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr. Biol. 16 (2006) 1041-1049
21. O'Rourke J.R., et al. Essential role for Dicer during skeletal muscle development. Dev. Biol. 311 (2007) 359-368
22. Harfe B.D., et al. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 10898-10903
23. Harris K.S., et al. Dicer function is essential for lung epithelium morphogenesis. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 2208-2213
24. Chen J.F., et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat. Genet. 38 (2006) 228-233
25. Rao P.K., et al. Myogenic factors that regulate expression of muscle-specific microRNAs. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 8721-8726
26. Wienholds E., et al. MicroRNA expression in zebrafish embryonic development. Science 309 (2005) 310-311
27. Krek A., et al. Combinatorial microRNA target predictions. Nat. Genet. 37 (2005) 495-500
28. Griffiths-Jones S., et al. miRBase: tools for microRNA genomics. Nucleic Acids Res. 36 (2008) D154-D158
29. Srivastava D., et al. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16 (1997) 154-160
30. Hunter J.J., and Chien K.R. Signaling pathways for cardiac hypertrophy and failure. N. Engl. J. Med. 341 (1999) 1276-1283
31. Heineke J., and Molkentin J.D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 7 (2006) 589-600
32. Frey N., and Olson E.N. Cardiac hypertrophy: the good, the bad, and the ugly. Annu. Rev. Physiol. 65 (2003) 45-79
33. Cheng Y., et al. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am. J. Pathol. 170 (2007) 1831-1840
34. Tatsuguchi M., et al. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J. Mol. Cell. Cardiol. 42 (2007) 1137-1141
35. Sayed D., et al. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ. Res. 100 (2007) 416-424
36. Xu C., et al. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J. Cell Sci. 120 (2007) 3045-3052
37. Chan J.A., et al. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65 (2005) 6029-6033
38. Cheng A.M., et al. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 33 (2005) 1290-1297
39. Si M.L., et al. miR-21-mediated tumor growth. Oncogene 26 (2006) 2799-2803
40. Rosamond W., et al. Heart disease and stroke statistics-2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117 (2008) e25-e146
41. Mandel E.M., et al. Transcriptional mechanisms of congenital heart disease. Drug Discov. Today 2 (2005) 33-38
42. Ransom J., and Srivastava D. The genetics of cardiac birth defects. Semin. Cell Dev. Biol. 18 (2007) 132-139
43. Clop A., et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat. Genet. 38 (2006) 813-818
44. Lee S.J. Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 20 (2004) 61-86
45. Schuelke M., et al. Myostatin mutation associated with gross muscle hypertrophy in a child. N. Engl. J. Med. 350 (2004) 2682-2688
46. Mardis E.R. The impact of next-generation sequencing technology on genetics. Trends Genet. 24 (2008) 133-141
47. Krutzfeldt J., et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438 (2005) 685-689
48. Esau C., et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab. 3 (2006) 87-98
49. Kwon C., et al. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 18986-18991
50. Sokol N.S., and Ambros V. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev. 19 (2005) 2343-2354
51. Boutz P.L., et al. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev. 21 (2007) 71-84
52. Meng F., et al. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133 (2007) 647-658
53. Zhu S., et al. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem. 282 (2007) 14328-14336
54. Filipowicz W., et al. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat. Rev. Genet. 9 (2008) 102-114