Metastable atom-activated dissociation mass spectrometry: Leucine/isoleucine differentiation and ring cleavage of proline residues

Journal of Mass Spectrometry

Volumn 44, Issue 8, 2009, Pages 1211-1223

  Cook, Shannon L ^a   Collin, Olivier L ^a   Jackson, Glen P ^a  

^a OHIO UNIVERSITY   (United States)

Author keywords

CAD; Leucine isoleucine; Metastable atom; Nonergodic fragmentation; Peptide sequencing; Post translational modifications; Quadrupole ion traps

Indexed keywords

CAD; LEUCINE/ISOLEUCINE; METASTABLE ATOM; NONERGODIC FRAGMENTATION; PEPTIDE SEQUENCING; POST TRANSLATIONAL MODIFICATIONS; QUADRUPOLE ION TRAPS;

AMINES; AMINO ACIDS; ARGON; ATOMS; DISSOCIATION; ELECTROCHEMICAL SENSORS; ELECTROCHROMIC DEVICES; FREE RADICAL REACTIONS; HELIUM; MASS SPECTROMETERS; MASS SPECTROMETRY; MOLECULAR BIOLOGY; PEPTIDES; REDUCTION;

IONS;

BRADYKININ; HELIUM; ION; ISOLEUCINE; LEUCINE; PROLINE; SUBSTANCE P;

AMINO ACID ANALYSIS; ARTICLE; ATOM; CHEMICAL BINDING; COVALENT BOND; DISSOCIATION; ELECTRICITY; ELECTRON CAPTURE DISSOCIATION; ELECTRON IONIZATION DISSOCIATION; ELECTRON TRANSFER DISSOCIATION; FRAGMENTATION REACTION; IONIZATION; MASS SPECTROMETRY; METASTABLE ATOM ACTIVATED DISSOCIATION MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; PROTEOMICS; WILD TYPE;

ANGIOTENSIN II; BRADYKININ; CHOLECYSTOKININ; DIPEPTIDES; FIBRINOPEPTIDE B; ISOLEUCINE; LEUCINE; MASS SPECTROMETRY; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PROLINE; PROTEINS; SUBSTANCE P;

EID: 70349144105     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1598     Document Type: Article

References (62)

1. K. L. Busch, G. L.Glish, S. A. McLuckey. Mass Spectrometry/Mass Spectrometry: Techniques and Applications of Tandem Mass Spectrometry, VCH Publishers: New York, 1988.
2. J. Laskin, J. H. Futrell. Collisional activation of peptide ions in FT-ICR mass spectrometry. Rapid Communications in Mass Spectrometry 2003, 17, 2694.
3. R. C. Dunbar, T. B. McMahon. Activation of unimolecular reactions by ambient blackbody radiation. Science 1998, 279, 194.
4. J. L. Stephenson Jr, R. A. Yost. Photodissociation in the ion trap. In Practical Aspects of Ion Trap Mass Spectrometry, vol.2, Chapter 5, R. E. March, J. F. J. Todd (eds). CRC Press: New York, 1995.
5. Z. Q. Guan, N. L. Kelleher, P. B. O'Connor, D. J. Aaserud, D. P. Little, F. W. McLafferty. 193 nm photodissociation of larger multiply-charged biomolecules. International Journal of Mass Spectrometry 1996, 158, 357.
6. D. P. Little, J. P. Speir, M. W. Senko, P. B. O'Connor, F. W. McLafferty. Infrared multiphoton dissociation of large multiply-charged ions for biomolecule sequencing. Analytical Chemistry 1994, 66, 2809.
7. W. J. Herron, D. E. Goeringer, S. A. McLuckey. Gas-phase electrontransfer reactions frommultiply-charged anions to rare-gas cations. Journal of the American Chemical Society 1995, 117, 11555.
8. R. A. Zubarev, N. L. Kelleher, F. W. McLafferty. Electron capture dissociation of multiply charged protein cations. A nonergodic process. Journal of the American Chemical Society 1998, 120, 3265.
9. L. Sleno, D. A. Volmer. Ion activation methods for tandem mass spectrometry. Journal of Mass Spectrometry 2004, 39, 1091.
10. E. A. Kapp, F. Schutz, G. E. Reid, J. S. Eddes, R. L. Moritz, R. A. J. O'Hair, T. P. Speed, R. J. Simpson. Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation. Analytical Chemistry 2003, 75, 6251.
11. B. Paizs, S. Suhai. Towards understanding the tandemmass spectra of protonated oligopeptides. 1: mechanism of amide bond cleavage. Journal of the American Society for Mass Spectrometry 2004, 15, 103.
12. A. Schlosser, W. D. Lehmann. Special feature: commentary - five-membered ring formation in unimolecular reactions of peptides: a key structural element controlling low-energy collision-induced dissociation of peptides. Journal of Mass Spectrometry 2000, 35, 1382.
13. D. L. Tabb, L. L. Smith, L. A. Breci, V. H. Wysocki, D. Lin, J. R. Yates. Statistical characterization of ion trap tandem mass spectra from doubly charged tryptic peptides. Analytical Chemistry 2003, 75, 1155.
14. S. A. McLuckey, D. E. Goeringer. Slow heating methods in tandem mass spectrometry. Journal of Mass Spectrometry 1997, 32, 461.
15. M. He, G. E. Reid, H. Shang, G. U. Lee, S. A. McLuckey. Dissociation of multiple protein ion charge states following a single gas-phase purification and concentration procedure. Analytical Chemistry 2002, 74, 4653.
16. J. M. Hogan, S. A. McLuckey. Charge state dependent collision induced dissociation of native and reduced porcine elastase. Journal of Mass Spectrometry 2003, 38, 245.
17. +). International Journal of Mass Spectrometry 2001, 212, 359.
18. A. J. Creese, H. J. Cooper. Liquid chromatography electron capture dissociation tandem mass spectrometry (LC-ECD-MS/MS) versus liquid chromatography collision-induced dissociation tandem mass spectrometry (LC-CID-MS/MS) for the identification of proteins. Journal of the American Society for Mass Spectrometry 2007, 18, 891.
19. D. M. Horn, Y. Ge, F. W. McLafferty. Activated ion electron capture dissociation for mass spectral sequencing of larger (42 kDa) proteins. Analytical Chemistry 2000, 72, 4778.
20. H. Satake, H. Hasegawa, A. Hirabayashi, Y. Hashimoto, T. Baba. Fast multiple electron capture dissociation in a linear radio frequency quadrupole ion trap. Analytical Chemistry 2007, 79, 8755.
21. N. Leymarie, C. E. Costello, P. B. O'Connor. Electron capture dissociation initiates a free radical reaction cascade. Journal of the American Chemical Society 2003, 125, 8949.
22. N. A. Kruger, R. A. Zubarev, B. K. Carpenter, N. L. Kelleher, D. M. Horn, F. W. McLafferty. Electron capture versus energetic dissociation of protein ions. International Journal of Mass Spectrometry 1999, 183, 1.
23. R. A. Zubarev, D. M. Horn, E. K. Fridriksson, N. L. Kelleher, N. A. Kruger, M. A. Lewis, B. K. Carpenter, F. W. McLafferty. Electron capture dissociation for structural characterization of multiply charged protein cations. Analytical Chemistry 2000, 72, 563.
24. R. A. Zubarev. Reactions of polypeptide ions with electrons in the gas phase. Mass Spectrometry Reviews 2003, 22, 57.
25. F. Kjeldsen, K. F. Haselmann, E. S. Sorensen, R. A. Zubarev. Distinguishing of Ile/Leu amino acid residues in the PP3 protein by (hot) electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry. Analytical Chemistry 2003, 75, 1267.
26. G. L. Glish, S. Ito, T. Baba, J. M. Bushey, N. Manri, H. Satake, T. Sakamoto, M. Watanabe, K. Yamada, K. Deguchi, H. Nakagawa. Liquid chromatography-tandemmass spectrometry using ion trap based electron capture dissociation. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO, 2008.
27. T. F. Greene, J. M. Bushey, T. Baba, G. L. Glish. Electron detachment dissociation in a hybrid radio frequency linear ion trap/time of flight mass spectrometer. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO, 2008.
28. J. J. Coon, J. E. P. Syka, J. C. Schwartz, J. Shabanowitz, D. F. Hunt. Anion dependence in the partitioning between proton and electron transfer in ion/ion reactions. International Journal of Mass Spectrometry 2004, 236, 33.
29. J. E. P. Syka, J. J. Coon, M. J. Schroeder, J. Shabanowitz, D. F. Hunt. Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 2004, 101, 9528.
30. D. M. Good, M. Wirtala, G. C. McAlister, J. J. Coon. Performance characteristics of electron transfer dissociation mass spectrometry. Molecular and Cellular Proteomics 2007, 6, 1942.
31. D. L. Swaney, G. C. McAlister, M. Wirtala, J. C. Schwartz, J. E. P. Syka, J. J. Coon. Supplemental activation method for high-efficiency electron-transfer dissociation of doubly protonated peptide precursors. Analytical Chemistry 2007, 79, 477.
32. S. J. Pitteri, P. A. Chrisman, S. A. McLuckey. Electron-transfer ion/ion reactions of doubly protonated peptides: effect of elevated bath gas temperature. Analytical Chemistry 2005, 77, 5662.
33. J. L. Stephenson Jr, S. A. McLuckey. Charge reduction of oligonucleotide anions via gas-phase electron transfer to xenon cations. Rapid Communications in Mass Spectrometry 1997, 11, 875.
34. M. Scigelova, A. Makarov. Orbitrap mass analyzer - overview and applications in proteomics. Proteomics 2006, 6, 16.
35. G. C. McAlister, D. Phanstiel, D. M. Good, W. T. Berggren, J. J. Coon. Implementation of electron-transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer. Analytical Chemistry 2007, 79, 3525.
36. F. Kjeldsen, O. A. Silivra, I. A. Ivonin, K. F. Haselmann, M. Gorshkov, R. A. Zubarev. C-alpha-C backbone fragmentation dominates in electron detachment dissociation of gas-phase polypeptide polyanions. Chemistry-A European Journal 2005, 11, 1803.
37. B. A. Budnik, K. F. Haselmann, R. A. Zubarev. Electron detachment dissociation of peptide di-anions: an electron-hole recombination phenomenon. Chemical Physics Letters 2001, 342, 299.
38. R. A. Zubarev, M. M. Savitski, E. M. Fung. New trends in ECD/ETD applications. 56th ASMS Conference on Mass Spectrometry and Allied Topics, Denvor, CO, 2008.
39. A. Armirotti, E. Millo, G. Damonte. How to discriminate between leucine and isoleucine by low energy ESI-TRAP MSn. Journal of the American Society for Mass Spectrometry 2007, 18, 57.
40. R. S. Johnson, S. A. Martin, K. Biemann, J. T. Stults, J. T. Watson. Novel fragmentation process of peptides by collision-induced decomposition in a tandem mass-spectrometer - differentiation of leucine and isoleucine. Analytical Chemistry 1987, 59, 2621.
41. T. Nakamura, H. Nagaki, Y. Ohki, T. Kinoshita. Differentiation of leucine and isoleucine residues in peptides by consecutive reaction mass-spectrometry. Analytical Chemistry 1990, 62, 311.
42. W. A. Tao, L. M. Wu, R. G. Cooks. Differentiation and quantitation of isomeric dipeptides by low-energy dissociation of copper(II)-bound complexes. Journal of the American Society for Mass Spectrometry 2001, 12, 490.
43. J. L. Seymour, F. Turecek. Distinction and quantitation of leucineisoleucine isomers and lysine-glutamine isobars by electrospray ionization tandem mass spectrometry (MSn, n = 2, 3) of copper(II)-diimine complexes. Journal of Mass Spectrometry 2000, 35, 566.
44. H. J. Cooper, R. R. Hudgins, K. Hakansson, A. G. Marshall. Secondary fragmentation of linear peptides in electron capture dissociation. International Journal of Mass Spectrometry 2003, 228, 723.
45. K. M. Choi, S. H. Yoon, M. L. Sun, J. Y. Oh, J. H. Moon, M. S. Kim. Characteristics of photodissociation at 193 nm of singly protonated peptides generated by matrix-assisted laser desorption ionization (MALDI). Journal of the American Society for Mass Spectrometry 2006, 17, 1643.
46. L. A. Breci, D. L. Tabb, J. R. Yates, V. H. Wysocki. Cleavage N-terminal to proline: analysis of a database of peptide tandem mass spectra. Analytical Chemistry 2003, 75, 1963.
47. V. D. Berkout. Fragmentation of protonated peptide ions via interaction with metastable atoms. Analytical Chemistry 2006, 78, 3055.
48. V. D. Berkout, V. M. Doroshenko. Fragmentation of phosphorylated and singly charged peptide ions via interaction with metastable ions. International Journal of Mass Spectrometry 2008, 278, 150.
49. A. S. Misharin, O. A. Silivra, F. Kjeldsen, R. A. Zubarev. Dissociation of peptide ions by fast atom bombardment in a quadrupole ion trap. Rapid Communications in Mass Spectrometry 2005, 19, 2163.
50. O. Collin, G. P. Jackson. Metastable-activated dissociation mass spectrometry (MAD-MS): a new paradigm for tandem mass spectrometry. 53rd ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, 2005.
51. R. A. Yost, D. D. Fetterolf. Tandem mass-spectrometry (MS/MS) instrumentation. Mass Spectrometry Reviews 1983, 2, 1.
52. H. J. Cooper, R. R. Hudgins, K. Hakansson, A. G. Marshall. Characterization of amino acid side chain losses in electron capture dissociation. Journal of the American Society for Mass Spectrometry 2002, 13, 241.
53. H. J. Cooper, K. Hakansson, A. G. Marshall. The role of electron capture dissociation in biomolecular analysis. Mass Spectrometry Reviews 2005, 24, 201.
54. M. M. Savitski, M. L. Nielsen, R. A. Zubarev. Side-chain losses in electron capture dissociation to improve peptide identification. Analytical Chemistry 2007, 79, 2296.
55. M. M. Savitski, F. Kjeldsen, M. L. Nielsen, R. A. Zubarev. Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides. Journal of the American Society for Mass Spectrometry 2007, 18, 113.
56. S. C. Moyer, R. J. Cotter, A. S. Woods. Fragmentation of phosphopeptides by atmospheric pressure MALDI and ESI/ion trap mass spectrometry. Journal of the American Society for Mass Spectrometry 2002, 13, 274.
57. H. Morgner. Photo- and Penning ionization of molecules in the gas phase and in the liquid phase. In Linking the Gaseous and Condensed Phases of Matter, L. G. Christophorouetal (ed). Plenum Press: New York, 1994.
58. F. M. Penning. Ionization by metastable atoms. Naturwissenschaften 1927, 15, 818.
59. P. E. Siska. Molecular-beam studies of Penning ionization. Reviews of Modern Physics 1993, 65, 337.
60. K. Ohno, S. Takano, K. Mase. Penning ionization electron spectroscopy of molecules containing the C O group: aldehydes and carboxylic acids. Journal of Physical Chemistry 1986, 90, 2015.
61. F. W. McLafferty. Interpretation of Mass Spectra: An Introduction. Benjamin: New York, 1967.
62. + ions of peptides - side-chain specific sequence ions. International Journal of Mass Spectrometry and Ion Processes 1988, 86, 137.