Ion activation methods for tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 39, Issue 10, 2004, Pages 1091-1112

  Sleno, Lekha ^a   Volmer, Dietrich A ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Blackbody infrared radiative dissociation; Collision induced dissociation; Electron capture dissociation; Infrared multiphoton dissociation; Ion activation; Surface induce dissociation; Tandem mass spectrometry

Indexed keywords

CHEMICAL ACTIVATION; CYCLOTRON RESONANCE; DECOMPOSITION; DISSOCIATION; INFRARED RADIATION; IONIZATION; MULTIPHOTON PROCESSES;

COLLISION INDUCED DISSOCIATION (CID); INFRARED MULTIPHOTON DISSOCIATION (IRMPD); ION ACTIVATION; SURFACE INDUCED DISSOCIATION (SID); TANDEM MASS SPECTROMETRY;

MASS SPECTROMETRY;

CIPROFLOXACIN; PURINE DERIVATIVE; THEOBROMINE;

ANALYTIC METHOD; COLLISIONALLY ACTIVATED DISSOCIATION; COVALENT BOND; DISSOCIATION CONSTANT; DRUG DETERMINATION; DRUG STRUCTURE; ELECTRON CAPTURE DETECTION; EXPERIMENTAL DESIGN; FRAGMENTATION REACTION; HUMAN; INTERMETHOD COMPARISON; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; ION TRAP MASS SPECTROMETRY; IONIZATION; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEOMICS; QUANTUM YIELD; REVIEW; SOLID STATE; STRUCTURE ANALYSIS; SURFACE PROPERTY; TANDEM MASS SPECTROMETRY; THEORETICAL STUDY; TIME OF FLIGHT MASS SPECTROMETRY;

CHEMISTRY, CLINICAL; HUMANS; MASS SPECTROMETRY; METABOLIC DISEASES; PHARMACOKINETICS; URINE;

EID: 6944233454     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.703     Document Type: Review

References (127)

1. Barber M, Bordoli RS, Sedgwick RD. In Soft Ionization Biological Mass Spectrometry, Morris HR (ed). Heyden: London, 1981; 137.
2. Yamashita M, Fenn JB. Electrospray ion source. Another variation on the free-jet theme. J. Phys. Chem. 1984; 88: 4451.
3. Yamashita M, Fenn JB. Negative ion production with the electrospray source. J. Phys. Chem. 1984; 88: 4671.
4. Karas M, Bachmann D, Bahr U, Hillenkamp F. Matrix-assisted ultraviolet laser desorption of non-volatile compounds. Int. J. Mass Spectrom. Ion Processes 1987; 78: 53.
5. Lorquet JC. In The Structure, Energetics and Dynamics of Organic Ions, Baer T, Ng CY, Powis I (eds). Wiley: Chichester, 1996; 167.
6. Rosenstock HM, Wallenstein MB, Wahrhartig A, Eyring H. Absolute rate theory for isolated systems and the mass spectra of polyatomic molecules. Proc. Natl. Acad. Sci. USA. 1952; 38: 667.
7. Marcus RA. Unimolecular dissociations and free radical recombination reactions. J. Chem. Phys. 1952; 20: 359.
8. Longevialle P. In Principes de la Spectrometrie de Masse des Substances Organiques. Masson: Paris, 1981; 21.
9. Gilbert RG, Smith SC. In Theory of Unimolecular and Recombination Reactions. Blackwell: Oxford, 1990; 52.
10. McLafferty FW, Tureček F. In Interpretation of Mass Spectra (4th edn). University Science Books: Mill Valley, CA, 1993; Ch. 7 (McLafferty rearrangement, radical ion fragmentations), 116 (metastable ions), 138 (relative fragmentation energies).
11. Williams DH, Cooks RG. The role of 'frequency factors' in determining the difference between low- and high-voltage mass spectra. Chem. Commun. 1968; 663.
12. Aston FW. The distribution of intensity along the positive ray parabolas of atoms and molecules of hydrogen and its possible explanation. Proc. Cambridge Philos. Soc. 1919; 19: 317.
13. Hipple JA, Condon EU. Detection of metastable ions with the mass spectrometer. Phys. Rev. 1945; 68: 54.
14. Spiteller G, Spiteller-Friedmann M. Vergleichende massen-spektrometrische Untersuchung einiger Purinderivate. Monatsh. Chem. 1962; 93: 632.
15. de Hoffmann E, Stroobant V. In Mass Spectrometry. Principles and Applications (2nd edn). Wiley: Chichester 2002; 108, 246.
16. Spengler B, Kirsch D, Kaufmann R. Fundamentals of post source decay in MALDI-MS. 1. Residual gas effects. J. Phys. Chem. 1992; 96: 9678.
17. Kaufmann R, Kirsh D, Spengler B. Sequencing of peptides in a time-of-flight mass spectrometer: evaluation of postsource decay following matrix-assisted laser desorption ionization (MALDI). Int. J. Mass Spectrom. Ion Processes 1994; 131: 355.
18. Karas M, Hillenkamp F. Laser desorption ionization of proteins with molecular masses exceeding 10000 daltons. Anal. Chem. 1988; 60: 2299.
19. Kaufmann R, Spengler B, Lützenkirchen F. Mass spectrometric sequencing of linear peptides by product-ion analysis in a reflectron time-of-flight mass spectrometer using matrix-assisted laser desorption ionization. Rapid Commun. Mass Spectrom. 1993; 7: 902.
20. Beynon JH, Cooks RG, Amy JM, Baitinger WE, Ridley TY. Design and performance of a mass-analysed ion kinetic energy (MIKE) spectrometer. Anal. Chem. 1973; 45: 1023A.
21. Walton TJ, Bayliss MA, Pereira ML, Games DE, Genieser H-G, Brenton AG, Harris FM, Newton RP. Fast-atom bombardment tandem mass spectrometry of cyclic nucleoside analogues used as site-selective activators of cyclic nucleotide-dependent protein kinases. Rapid Commun. Mass Spectrom. 1998; 12: 449.
22. Frański R, Gierczyk B, Fiedorow P, Chadyniak D, Urbaniak W. Investigation of 4-(nitrophenylamino)pent-3-en-2-ones and 4-(nitrobenzylamino)pent-3-en-2-ones by electron ionization mass spectrometry. Observation of characteristic ortho effects. Eur. J. Mass Spectrom. 2003; 9: 465.
23. Cooks RG, Beynon JH, Caprioli RM, Lester GR. Metastable Ions. Gross ML (ed.). Elsevier: Amsterdam 1973; 57.
24. Bruins AP, Jennings KR. The observation of metastable transitions in a double-focusing mass spectrometer using a linked scan of the electric sector and magnetic sector fields. Int. J. Mass Spectrom. 1978; 26: 395.
25. Jenning KR. High Performance Mass Spectrometry: Chemical Applications: a Symposium. American Chemical Society: Washington, DC, 1978; 3.
26. Boyd RK, Porter CJ, Beynon JH. A new linked scan for reversed geometry mass spectrometers. Org. Mass Spectrom. 1981; 16: 493.
27. Haddon WF. The constant neutral linked magnetic field-electric sector scan. Org. Mass Spectrom. 1980; 15: 539.
28. McLuckey SA. Principles of collisional activation in analytical mass spectrometry. J. Am. Soc. Mass Spectrom. 1992; 3 599.
29. Shukla AK, Futrell JH. Tandem mass spectrometry: dissociation of ions by collisional activation. J. Mass Spectrom. 2000; 35 1069.
30. Jennings KR. The changing impact of the collision-induced decomposition of ions on mass spectrometry. Int. J. Mass Spectrom. 2000; 200: 479.
31. Levsen K. In Fundamental Aspects of Organic Mass Spectrometry. Verlag Chemie: Weinheim, 1978; 138 (collision process), 92 (energy dependence of CID products).
32. Cooks RG. In Collision Spectroscopy. Plenum Press: New York, 1979; 8 (Newton diagrams), 372 (QET fragmentation).
33. com), 84 (pressure effects).
34. Durup J. In Recent Developments in Mass Spectrometry, Ogata K, Hayakawa T (eds). University Park Press: Baltimore, MD, 1970; 921.
35. McLuckey SA, Goeringer DE. Slow heating methods in tandem mass spectrometry. J. Mass Spectrom. 1997; 32: 461.
36. Gauthier JW, Trautman TR, Jacobson DB. Sustained off-resonance irradiation for collision-activated dissociation involving Fourier transform mass spectrometry. Collision-activated dissociation technique that emulates infrared multiphoton dissociation. Anal. Chim. Acta 1991; 246: 211.
37. Schwartz RN, Slawsky ZI, Herzfeld KF. Calculation of vibrational relaxation times in gases. J. Chem. Phys. 1952; 20 1591.
38. Volmer DA, Mansoori B, Locke SJ. Study of 4-quinolone antibiotics in biological samples by short-column liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Anal. Chem. 1997; 69: 4143.
39. Chace DH, Hillman SL, Millington DS, Kahler SG, Adam BW, Levy HL. Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry. Clin. Chem. 1996; 42: 349.
40. trap (Q TRAP™) mass spectrometer. Rapid Commun. Mass Spectrom. 2003; 17: 1056.
41. Chernushevich IV, Loboda AV, Thomson BA. An introduction to quadrupole-time-of-flight mass spectrometry. J. Mass Spectrom. 2001; 36: 849.
42. Akashi S, Takio K. Structure of melittin bound to phospholipid micelles studied using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. J. Am. Soc. Mass Spectrom. 2001; 12: 1247.
43. Olsen JV, Ong S-E, Mann M. Trypsin cleaves exclusively C-terminal to arginine and lysine residues. Mol. Cell. Proteomics 2004; 3: 608.
44. Spengler B. Post-source decay analysis in matrix-assisted laser desorption/ionization mass spectrometry of biomolecules. J. Mass Spectrom. 1997; 32: 1019.
45. Cotter RJ. In Time-of-Flight Mass Spectrometry: Instrumentation and Applications in Biological Research. American Chemical Society: Washington, DC, 1997; 204.
46. 2H. J. Chem. Phys. 1969; 51: 3465.
47. Franchetti V, Freiser BS, Cooks RG. Excitation in ion-molecule collisions. A study of protonated aromatic molecules by ion kinetic energy spectrometry. Org. Mass Spectrom. 1978; 13: 106.
48. Beynon JH, Boyd RK, Brenton AG. In Advances in Mass Spectrometry (1985), Todd JFJ (ed). Wiley: New York, 1986; 437.
49. Wysocki V, Kenttämaa HI, Cooks RG. Internal energy distributions of isolated ions after activation by various methods. Int. J. Mass Spectrom. Ion Processes 1987; 75: 181.
50. Biemann K. Contributions of mass spectrometry to peptide and protein structure. Biomed. Environ. Mass Spectrom. 1988; 16: 99.
51. Papayannopoulos IA. The interpretation of collision-induced dissociation tandem mass spectra of peptides. Mass Spectrom. Rev. 1995; 14: 49.
52. Schlosser A, Lehmann WD. Five-membered ring formation in unimolecular reactions of peptides: a key structural element controlling low-energy collision-induced dissociation of peptides. J. Mass Spectrom. 2000; 35: 1382.
53. Fabris D, Kelly M, Murphy C, Wu Z, Fenselau C. High-energy collision-induced dissociation of multiply charged polypeptides produced by electrospray. J. Am. Soc. Mass Spectrom. 1993; 4: 652.
54. Cooks RG, Ast T, Beynon JH. Anomalous metastable peaks. Int. J. Mass Spectrom. Ion Phys. 1975; 16: 348.
55. Cooks RG, Ast T, Mabud MdA. Collisions of polyatomic ions with surfaces. Int. J. Mass Spectrom. Ion Processes 1990; 100 209.
56. Williams ER, Henry KD, McLafferty FW, Shabanowitz J, Hunt DF. Surface-induced dissociation of peptide ions in Fourier-transform mass spectrometry. J. Am. Soc. Mass Spectrom. 1990; 1: 413.
57. Chorush RA, Little DP, Beu SC, Wood TD, McLafferty FW. Surface-induced dissociation of multiply-protonated proteins. Anal. Chem. 1995; 67: 1042.
58. Schaaff TG, Qu Y, Farrell N, Wysocki VH. Investigation of the trans effect in the fragmentation of dinuclear platinum complexes by electrospray ionization surface-induced dissociation tandem mass spectrometry. J. Mass Spectrom. 1998; 33: 436.
59. Nair H, Somogyi Á, Wysocki VH. Effect of alkyl substitution at the amide nitrogen on amide bond cleavage electrospray ionization/surface-induced dissociation fragmentation of substance P and two alkylated analogs. J. Mass Spectrom. 1996; 31: 1141.
60. Dongré AR, Somogyi Á, Wysocki VH. Surface-induced dissociation: an effective tool to probe structure, energetics and fragmentation mechanisms of protonated peptides. J. Mass Spectrom. 1996; 31: 339.
61. Laskin J, Denisov EV, Shukla AK, Barlow SE, Futrell JH. Surface-induced dissociation in a Fourier transform ion cyclotron resonance mass spectrometer: instrument design and evaluation. Anal. Chem. 2002; 74: 3255.
62. Laskin J, Bailey TH, Futrell JH. Shattering of peptide ions on self-assembled monolayer surfaces. J. Am. Chem. Soc. 2003; 125: 1625.
63. Laskin J, Beck KM, Hache JJ, Futrell JH. Surface-induced dissociation of ions produced by matrix-assisted laser desorption/ionization in a Fourier transform ion cyclotron resonance mass spectrometer. Anal. Chem. 2004; 76: 351.
64. Laskin J, Futrell JH. Collisional activation of peptide ions in FT-ICR mass spectrometry. Mass Spectrom. Rev. 2003; 22: 158.
65. Grill V, Shen J, Evans C, Cooks RG. Collisions of ions with surfaces at chemically relevant energies: instrumentation and phenomena. Rev. Sci. Instrum. 2001; 72: 3149.
66. Franchetti V, Solka BH, Baitinger WE, Amy JW, Cooks RG. Soft landing of ions as a means of surface modification. Int. J. Mass Spectrom. Ion Phys. 1977; 23: 29.
67. Laskin J, Futrell JH. Surface-induced dissociation of peptide ions: kinetics and dynamics. J. Am. Soc. Mass Spectrom. 2003; 14 1340.
68. Schulz DG, Lim H, Garbis S, Hanley L. Energy partitioning in the surface-induced dissociation of linear and cyclic protonated peptides at an organic surface. J. Mass Spectrom. 1999; 34: 217.
69. Wysocki VH, Ding J-M, Jones JL, Callahan JH, King FL. Surface-induced dissociation in tandem quadrupole mass spectrometers: a comparison of three designs. J. Am. Soc. Mass Spectrom. 1992; 3 27.
70. Meroueh O, Hase WL. Dynamics of energy transfer in peptide-surface collisions. J. Am. Soc. Chem. 2002; 124: 1524.
71. Murata Y. In Unimolecular and Bimolecular Ion-Molecule Reaction Dynamics, Ng CY, Baer T, Powis I (eds). Wiley: Chichester, 1994; 427.
72. Ast T, Mabud MdA, Cooks RG. Reactive collisions of polyatomic ions at solid surfaces. Int. J. Mass Spectrom. Ion Processes 1988; 82: 131.
73. 2+ ions. J. Am. Soc. Chem. 1988; 110: 1343.
74. + at self-assembled monolayer films prepared on gold from n-alkanethiols and a fluorinated alkanethiol: the influence of chain length on the reactivity of the films and the neutralization of the projectile. J. Am. Chem. Soc. 1993; 115 5275.
75. 5 as probes for the characterization of self-assembled monolayer films on gold. Org. Mass Spectrom. 1993; 28: 1665.
76. Bier ME, Amy JW, Cooks RG, Syka JEP, Ceja P, Stafford G. A tandem quadrupole mass spectrometer for the study of surface-induced dissociation. Int. J. Mass Spectrom. Ion Processes 1987; 77: 31.
77. Schey K, Cooks RG, Grix R, Wollnik H. A tandem time-of-flight mass spectrometer for surface-induced dissociation. Int. J. Mass Spectrom. Ion Processes 1987; 77: 49.
78. Williams ER, Fang L, Zare RN. Surface induced dissociation for tandem time-of-flight mass spectrometry. Int. J. Mass Spectrom. Ion Processes 1993; 123: 233.
79. Schey KL, Cooks RG, Kraft A, Grix R, Wollnik H. Ion/surface collision phenomena in an improved tandem time-of-flight instrument. Int. J. Mass Spectrom. Ion Processes 1989; 94: 1.
80. Beck RD, St. John P, Homer ML, Whetten RL. Impact-induced cleaving and melting of alkali-halide nanocrystals. Science 1991; 253: 879.
81. St. John PM, Beck RD, Whetten RL. Reactions in cluster-surface collisions. Phys. Rev. Lett. 1992; 69: 1467.
82. St. John PM, Whetten RL. Hyperthermal collisions of silicon clusters with solid surfaces. Chem. Phys. Lett. 1992; 196: 330.
83. Ijames CF, Wilkins CL. Surface-induced dissociation by Fourier transform mass spectrometry. Anal. Chem. 1990; 62: 1295.
84. Castoro JA, Nuwaysir LM, Ijames CF, Wilkins CL. Comparative study of photodissociation and surface-induced dissociation by laser desorption Fourier transform mass spectrometry. Anal. Chem 1992; 64: 2238.
85. Lammert SA, Cooks RG. Surface-induced dissociation of molecular ions in a quadrupole ion trap mass spectrometer. J. Am. Soc. Mass Spectrom. 1991; 2: 487.
86. McLafferty FW, Amster IJ, Furlong JJP, Loo JA, Wang BH, Williams ER. In Fourier Transform Mass Spectrometry: Evolution Innovation and Applications. ACS Symposium Series, No. 359, Buchanan MV (ed). American Chemical Society: Washington, DC 1987; 116.
87. Zubarev RA, Kelleher NL, McLafferty FW. Electron capture dissociation of multiply charged protein cations. A nonergodic process. J. Am. Soc. Chem. 1998; 120: 3265.
88. Zubarev RA, Haselmann KF, Budnik B, Kjeldsen F, Jensen F. Towards an understanding of the mechanism of electron-capture dissociation: a historical perspective and modern ideas. Eur. J. Mass Spectrom. 2002; 8: 337.
89. McLafferty FW, Horn DM, Breuker K, Ge Y, Lewis MA, Cerda B, Zubarev RA, Carpenter BK. Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance. J. Am. Soc. Mass Spectrom. 2001; 12: 245.
90. Haselmann KF, Budnik BA, Olsen JV, Nielsen ML, Reis CA, Clausen H, Johnson AH, Zubarev RA. Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry. Anal. Chem. 2001; 73: 2998.
91. Zubarev RA. Reactions of polypeptide ions with electrons in the gas phase. Mass Spectrom. Rev. 2003; 22: 57.
92. Bardsley JN, Bionidi MA. In Advances in Atomic and Molecular Physics, vol. 6, Bates DR (ed). Academic Press: New York, 1970; 5.
93. Zubarev RA, Horn DM, Fridriksson EK, Kelleher NL, Kruger NA, Lewis MA, Carpenter BK, McLafferty FW. Electron capture dissociation for structural characterization of multiply charged protein cations. Anal. Chem. 2000; 72: 563.
94. Kjeldsen F, Haselmann KF, Budnik BA, Jensen F, Zubarev RA. Dissociation capture of hot (3-13 eV) electrons by polypeptide polycations: an efficient process accompanied by secondary fragmentation. Chem. Phys. Lett. 2002; 356: 201.
95. Tureček F, McLafferty FW. Non-ergodic behavior in acetone-enol ion dissociations. J. Am. Chem. Soc. 1984; 106: 2525.
96. Horn DM, Ge Y, McLafferty FW. Activated ion electron capture dissociation for mass spectral sequencing of larger (42 kDa) proteins. Anal. Chem. 2000; 72: 4778.
97. Cerda BA, Horn DM, Breuker K, Carpenter BK, McLafferty FW. Electron capture dissociation of multiply charged oxygenated cations. A nonergodic process. Eur. J. Mass Spectrom. 1999; 5: 335.
98. Cerda BA, Breuker K, Horn DM, McLafferty FW. Charge/radical site initiation versus coulombic repulsion for cleavage of multiply charged ions. Charge solvation in poly(alkene glycol) ions. J. Am. Soc. Mass Spectrom. 2001; 12: 565.
99. Olsen JV, Haselmann KF, Nielsen ML, Budnik BA, Nielsen PE, Zubarev RA. Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids. Rapid Commun. Mass Spectrom. 2001; 15: 969.
100. Håkansson K, Hudgins RR, Marshall AG, O'Hair RAJ. Electron capture dissociation and infrared multiphoton dissociation of oligodeoxynucleotide dications. J. Am. Soc. Mass Spectrom. 2003; 14: 23.
101. Håkansson K, Cooper HJ, Emmett MR, Costello CE, Marshall AG, Nilsson CL. Electron capture dissociation and infrared multiphoton dissociation MS/MS of an N-glycosylated tryptic peptide to yield complementary sequence information. Anal. Chem. 2001; 73: 4530.
102. Thorne LR, Beauchamp JL. In Gas Phase Ion Chemistry. Vol. 3: Ions and Light, MT Bowers (ed). Academic Press: London, 1984; 41.
103. van der Hart WJ. Studies of ion structures by photodissociation. Int. J. Mass Spectrom. Ion Processes 1992; 118/119: 617.
104. Uechi GT, Dunbar RC. The kinetics of infrared laser photodissociation of n-butylbenzene ions at low pressure. J. Chem. Phys. 1992; 96: 8897.
105. Colorado A, Shen JX, Vartanian VH, Brodbelt J. Use of infrared multiphoton photodissociation with SWIFT for electrospray ionization and laser desorption applications in a quadrupole ion trap mass spectrometer. Anal. Chem. 1996; 68: 4033.
106. Marshall AG, Wang TCL, Ricca TL. Tailored excitation for Fourier transform ion cyclotron resonance mass spectrometry. J. Am. Chem. Soc. 1985; 107: 7893.
107. Hofstadler SA, Sannes-Lowery KA, Griffey RH. Infrared multiphoton dissociation in an external ion reservoir. Anal. Chem. 1999; 71: 2067.
108. Hofstadler SA, Drader JJ, Gaus H, Hannis JC, Sannes-Lowery KA. Alternative approaches to infrared multiphoton dissociation in an ion external reservoir. J. Am. Soc. Mass Spectrom. 2003; 14: 1413.
109. Little DP, Speir JP, Senko MW, O'Connor PB, McLafferty FW. Infrared multiphoton dissociation of large multiply charged ions for biomolecule sequencing. Anal. Chem. 1994; 66: 2809.
110. Li W, Hendrickson CL, Emmett MR, Marshall AG. Identification of intact proteins in mixtures by alternated capillary liquid chromatography electrospray ionization and LC ESI infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry. Anal. Chem. 1999; 71: 4397.
111. Xie Y, Lebrilla CB. Infrared multiphoton dissociation of alkali metal-coordinated oligosaccharides. Anal. Chem. 2003; 75 1590.
112. Little DP, Aaserud DJ, Valaskovic GA, McLafferty FW. Sequence information from 42-108-mer DNAs (complete for a 50-mer) by tandem mass spectrometry. J. Am. Chem. Soc. 1996; 118: 9352.
113. Sannes-Lowery KA, Hofstadler SA. Sequence confirmation of modified oligonucleotides using IRMPD in the external ion reservoir of an electrospray ionization Fourier transform ion cyclotron mass spectrometer. J. Am. Soc. Mass Spectrom. 2003; 14: 825.
114. Goolsby BJ, Brodbelt JS. Analysis of protonated and alkali metal cationized aminoglycoside antibiotics by collision-activated dissociation and infrared multiphoton dissociation in the quadrupole ion trap. J. Mass Spectrom. 2000; 35: 1011.
115. Crowe MC, Brodbelt JS, Goolsby BJ, Hergenrother P. Characterization of erythromycin analogs by collisional activated dissociation and infrared multiphoton dissociation in a quadrupole ion trap. J. Am. Soc. Mass Spectrom. 2002; 13: 630.
116. Håkansson K, Chalmers MJ, Quinn JP, McFarland MA, Hendrickson CL, Marshall AG. Combined electron capture and infrared multiphoton dissociation for multistage MS/MS in a Fourier transform ion cyclotron resonance mass spectrometer. Anal. Chem. 2003; 75: 3256.
117. Tsybin YO, Witt M, Bayhut G, Kjeldsen F, Håkansson P. Combined infrared multiphoton dissociation and electron capture dissociation with a hollow electron beam in Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun. Mass Spectrom. 2003; 17: 1759.
118. Hashimoto Y, Hasegawa H, Yoshinari K, Waki I. Collision-activated infrared multiphoton dissociation in a quadrupole ion trap mass spectrometer. Anal. Chem. 2003; 75: 420.
119. Price WD, Schnier PD, Williams ER. Tandem mass spectrometry of large biomolecule ions by blackbody infrared radiative dissociation. Anal. Chem. 1996; 68: 859.
120. Price WD, Schnier PD, Jockusch RA, Strittmatter EF, Williams ER. Unimolecular reaction kinetics in the high-pressure limit without collisions. J. Am. Chem. Soc. 1996; 118: 10 640.
121. Price WD, Williams ER. Activation of peptide ions by blackbody radiation: factors that lead to dissociation kinetics in the rapid energy exchange limit. J. Phys. Chem. A 1997; 101: 8844.
122. Dunbar RC, McMahon TB. Activation of unimolecular reactions by ambient blackbody radiation. Science 1998; 279: 194.
123. Benson SW. In Thermochemical Kinetics. Methods for the Estimation of Thermochemical Data and Rate Parameters. Wiley: New York, 1968; 70, 80.
124. Freitas MA, Hendrickson CL, Marshall AG. Gas phase activation energy for unimolecular dissociation of biomolecular ions determined by focused radiation for gaseous multiphoton energy transfer (FRAGMENT) Rapid Commun. Mass Spectrom. 1999; 13: 1639.
125. Klassen JS, Schnier PD, Williams ER. Blackbody infrared radiative dissociation of oligonucleotide anions. J. Am. Soc. Mass Spectrom. 1998; 9: 1117.
126. Jockusch RA, Schnier PD, Price WD, Strittmatter EF, Demirev PA, Williams ER. Effects of charge state on fragmentation pathways, dynamics, and activation energies of ubiquitin ions measured by blackbody infrared radiative dissociation. Anal. Chem. 1997; 69: 1119.
127. Felitsyn N, Kitova EN, Klassen JS. Thermal decomposition of a gaseous multiprotein complex studied by blackbody infrared radiative dissociation. Investigating the origin of the asymmetric dissociation behavior. Anal. Chem. 2001; 73: 4647.