Ultrasound-enhanced transdermal transport

Journal of Pharmaceutical Sciences

Volumn 92, Issue 6, 2003, Pages 1125-1137

  Merino, Gustavo ^a,b   Kalia, Yogeshvar N ^a,b   Guy, Richard H ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Centre Interuniversitaire Recherche   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BUTANOL; CORTICOSTERONE; EMLA; ERYTHROPOIETIN; ESTRADIOL; FLUOCINOLONE ACETONIDE; GAMMA INTERFERON; HEPARIN; HYDROCORTISONE; INSULIN; LIDOCAINE; LOW MOLECULAR WEIGHT HEPARIN; PREDNISOLONE; SALICYLIC ACID DERIVATIVE; SUCROSE; WATER;

CLINICAL TRIAL; DERMIS; DEVICE; DIAGNOSTIC TEST; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG METABOLISM; ENERGY; HUMAN; IN VITRO STUDY; NONHUMAN; PHYSICS; REVIEW; SAFETY; SKIN ABSORPTION; STRATUM CORNEUM; THERMAL ANALYSIS; ULTRASOUND;

EID: 0037945771     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10369     Document Type: Review

References (69)

1. Zagzebski JA. 1996. Physics of diagnostic ultrasound. In: Lading DE, Potts L, editors. Essentials of ultrasound physics. St. Louis, MO: Mosby-Year Book, pp. 1-19.
2. Weyman AE. 1994. Physical principles of ultrasound. In: Weyman AE, editor. Principles and practice of echocardiography. Philadelphia: Lea and Febiger, pp. 3-28.
3. Benwell AD, Bly SHP. 1987. Sources and applications of ultrasound. In: Repacholi MH, Grandolfo M, Rindi A, editors. Ultrasound: Medical application, biological effects and hazard potentials. New York: Plenum Press. pp. 29-47.
4. Skauen DM, Zentner GM. 1984. Phonophoresis. Int J Pharm 20:235-245.
5. McElnay JC, Matthews MP, Harland R, McCafferty DF. 1985. The effect of ultrasound on the percutaneous absorption of lignocaine. Br J Clin Pharmacol 20:421-424.
6. Mitragotri S, Blanckschtein D, Langer R. 1996. Transdermal drug delivery using low frequency sonophoresis. Pharm Res 13:411-420.
7. Kost J, Mitragotri S, Gabbay RA, Pishko M, Langer R. 2000. Transdermal monitoring of glucose and other analytes using ultrasound. Nature Med 6:327-350.
8. Walters KA. 1989. Stratum corneum: Biological and biochemical considerations. In: Hadgraft J, Guy RH, editors. Transdermal drug delivery: Development issues and research initiatives. New York: Marcel Dekker, pp. 23-57.
9. Kim N, El-Kattan AF, Asbill CS, Kennette RJ, Sowell JW Sr, Latour R, Michniak BB. 2001. Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine)-hexahydro-1H-azepine-2-one as dermal penetration enhancers: Side chain length variation and molecular modeling. J Controlled Release 73:183-196.
10. Guy RH, Kalia YN, Delgado-Charro MB, Merino V, Lopez A, Marro D. 2000. Iontophoresis: Electrorepulsion and electroosmosis. J Controlled Release 64:129-132.
11. Dujardin N, Van Der Smissen P, Preat V. 2001. Topical gene transfer into rat skin using electroporation. Pharm Res 18:61-66.
12. Mitragotri S, Blanckschtein D, Langer R. 1997. An explanation for the variation of the sonophoretic transdermal transport enhancement from drug to drug. J Pharm Sci 86:1190-1192.
13. Bommanan DB, Menon GK, Okuyama H, Elias PM, Guy RH. 1992. Sonophoresis I. The use of high-frequency ultrasound to enhance transdermal drug delivery. Pharm Res 9:559-564.
14. Brucks R, Nanavaty M, Jung D, Siegel F. 1989. The effect of ultrasound on the in vitro penetration of ibuprofen through human epidermis. Pharm Res 6:697-701.
15. Hikima T, Hirai Y, Tojo K. 1998. Effect of ultrasound application on skin metabolism of prednisolone 21-acetate. Pharm Res 15:1680-1683.
16. Novak EJ. 1964. Experimental transmission of lidocaine through intact skin by ultrasound. Arch Phys Med Rehab 45:231-232.
17. McElnay JC, Matthews MP, Harland R, McCafferty DF. 1985. The effect of ultrasound on the percutaneous absorption of lignocaine. Br J Clin Pharmacol 20:421-424.
18. McElnay JC, Matthews MP, Harland H. 1985. The influence of ultrasound on the percutaneous absorption of fluocinolona acetonide. Int J Pharm 40:421-424.
19. Benson HAE, McElnay JC, Harland R. 1998. Phonophoresis of lignocaine and prilocaine from Emla cream. Int J Pharm 44:65-69.
20. Weimann LJ, Junru W. 1999. Enhancement of skin penetration of Poly-L-lysine by ultrasound. Proceed Intl Symp Controlled Release Bioact Mater 26:417-418.
21. Ter Haar GR. 1988. Biological effects of ultrasound in clinical applications. In: Suslick KS, editor. Ultrasound: Its chemical, physical, and biological effects. New York: VCH Publishers, pp. 305-320.
22. Meidan VM, Walmsley AD, Docker MF, Irwin WJ. 1999. Ultrasound-enhanced diffusion into coupling gel during phonophoresis of 5-fluorouracil. Int J Pharm 185:205-213.
23. Machet L, Pinton J, Patat F, Arbeille B, Pourcelot L, Vaillant L. 1996. In vitro phonophoresis of digoxin across hairless mice and human skin: Thermal effect of ultrasound. Int J Pharm 133:39-45.
24. Machet L, Cochelin N, Patat F, Arbeille B, Machet MC, Lorette G, Vaillant L. 1998. In vitro phonophoresis of mannitol, oestradiol and hydrocortisone across human and hairless mouse. Int J Pharm 165:169-174.
25. Ueda H, Sugibayashi K, Morimoto Y. 1995. Skin penetration-enhancing effects of drugs by phonophoresis. J Controlled Release 37:291-297.
26. Liu J, Lewis TN, Prausnitz MR. 1998. Non-invasive assessment and control of ultrasound-mediated membrane permeabilization. Pharm Res 15:918-924.
27. Menon KG, Bommannan DB, Elias PM. 1994. High frequency sonophoresis: Permeation pathways and structural basis for enhanced permeability. Skin Pharmacol 7:130-1239.
28. Bommanan DB, Menon GP, Okuyama H, Elias PM, Guy RH. 1992. Sonophoresis II. Examination of the mechanisms of ultrasound-enhanced transdermal drug delivery. Pharm Res 9:1043-1047.
29. Potts RO, Francoeur ML. 1990. Lipid biophysics of water loss trough the skin. Proc Natl Acad Sci 87:3871-3873.
30. Benson HA, McElnay JC, Harland R, Hadgraft J. 1991. Influence of ultrasound on the percutaneous absorption of nicotinate esters. Pharm Res 8:204-209.
31. McElnay JC, Benson HA, Harland R, Hadgraft J. 1993. Phonophoresis of methyl nicotinate: A preliminary study to elucidate the mechanism of action. Pharm Res 10:1726-1731.
32. Monti D, Giannelli R, Trivella MG, Saettone MF. 1998. Ultrasonically-enhanced transdermal drug delivery. Proc 2nd World Meeting APFI/APV 905-906.
33. Merino G, Kalia YN, Delgado-Charro MB, Potts RO, Guy RH. 1999. Sonophoresis: How does ultrasound enhance drug transport across the skin?. Proceed Intl Symp Controlled Release Bioact Mater 26:383-384.
34. Anthony AA, Crum LA. 1988. Acoustic cavitation and bubble dynamics. In: Suslick KS, editor. Ultrasound: Its chemical, physical, and biological effects. New York: VCH Publishers, pp. 305-320.
35. Griffin JE, Touchstone JC. 1972. Effects of US frequency on cortisone into swine tissue. Am J Phys Med 51:62-78.
36. Flynn GL, Durrheim H, Higuchi WI. 1981. Permeation of hairless mouse skin II: Membrane sectioning techniques and influence on alkanol permeabilities. J Pharm Sci 70:52-56.
37. Mitragotri S, Kost J. 2001. Transdermal delivery of heparin and low-molecular weight heparin using low-frequency ultrasound. Pharm Res 18:1151-1156.
38. Tachibana K. 1992. Transdermal delivery of insulin to alloxan-diabetic rabbits by ultrasound exposure. Pharm Res 7:952-954.
39. Tachibana K, Tachibana S. 1993. Transdermal delivery of insulin by ultrasonic vibration. J Pharm Pharmacol 43:270-271.
40. Mitragotri S, Blanckschtein D, Langer R. 1995. Ultrasound-mediated transdermal protein delivery. Science 269:850-853.
41. Strickler HD, Wylie-Rosett J, Rohan T, Hoover DR, Smoller S, Burk RD, Yu H. 2001. The relation of type 2 diabetes and cancer. Diabetes Technol Ther 3:263-274.
42. See www.glucowatch.com and www.cygn.com
43. Cantrell JT, McArthur MJ, Pishko MV. 2000. Transdermal extraction of interstitial fluid by low-frequency ultrasound quantified with 3H2O as a tracer molecule. J Pharm Sci 89:1170-1179.
44. Mitragotri S, Coleman M, Kost J, Langer R. 2000. Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels. J App Physiol 89:961-966.
45. Mitragotri S, Coleman M, Kost J, Langer R. 2000. Transdermal extraction of analytes using low-frequency ultrasound. Pharm Res 17:466-470.
46. Terahara T, Mitragotri S, Kost J, Langer R. 1999. Influence of ultrasonic parameters on low-frequency sonophoresis. Proceed Intl Symp Controlled Release Bioact Mater 26:437-438.
47. Mitragotri S, Farrell J, Tang H, Terahara T, Kost J, Langer R. 2000. Determination of threshold energy dose for ultrasound-induced transdermal drug transport. J Controlled Release 63:41-52.
48. Fang J, Fang C, Sung KC, Chen H. 1999. In vitro percutaneous absorption of clobetasol-17-propionate. Int J Pharm 191:33-42.
49. Wu J, Chappelow J, Yang J, Weimann L. 1998. Defects generated in human stratum corneum specimens by ultrasound. Ultrasound Med Biol 24:705-710.
50. Singer AJ, Homan CS, Church AL, McClain SA. 1998. Low-frequency sonophoresis: Pathologic and thermal effects in dogs. Acad Emerg Med 5:35-40.
51. Boucaud A, Montharu J, Machet L, Arbeille B, Machet MC, Patat F, Vaillant L. 2001. Clinical, histologic, and electron microscopy study of skin exposed to low-frequency ultrasound. Anat Rec 264:114-119.
52. Boucaud A, Machet L, Arbeille B, Machet MC, Sournac M, Mavon A, Patat F, Vaillant L. 2001. In vitro study of low-frequency ultrasound-enhanced transdermal transport of fentanyl and caffeine across human and hairless rat skin. Int J Pharm 228:69-77.
53. Johnson ME, Mitragotri S, Patel A, Blankschtein D, Langer R. 1996. Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery. J Pharm Sci 85:670-679.
54. Ueda H, Isshiki R, Ogihara M, Sugibayashi K, Morimoto Y. 1996. Combined effect of ultrasound and chemical enhancers on the skin permeation of aminopyrine. Int J Pharm 143:37-45.
55. Meidan VM, Docker MF, Walmsley AD, Irwin WJ. 1998. Phonophoresis of hydrocortisone with enhancers: an acoustically defined model. Int J Pharm 170:157-168.
56. Mitragotri S, Ray D, Farrell J, Tang H, Yu B, Kost J, Blankschtein D, Langer R. 2000. Synergistic effect of low-frequency ultrasound and sodium lauryl sulfate on transdermal transport. J Pharm Sci 89:892-900.
57. Mitragotri S. 2000. Synergistic effect of enhancers for transdermal drug delivery. Pharm Res 17:1354-1359.
58. Williams AC, Barry BW. 1991. Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement. Pharm Res 8:17-24.
59. Barry BW. 1987. Mode of action of penetration enhancers in human skin. J Controlled Release 6:85-97.
60. Le L, Kost J, Mitragotri S. 2000. Combined effect of low-frequency ultrasound and iontophoresis: Applications for transdermal heparin delivery. Pharm Res 17:1151-1154.
61. Kost J, Pliquett U, Mitragotri S, Yamamoto A, Langer R, Weaver J. 1996. Synergistic effect of electric field and ultrasound on transdermal transport. Pharm Res 13:633-638.
62. Potts RO. 1989. Physical characterization of the stratum corneum: The relationship of mechanical and barrier properties to lipid and protein structure. In: Hadgraft J, Guy RH, editors. Transdermal drug delivery. Developmental issues and research initiatives. New York: Marcel Dekker, pp. 23-57.
63. Merino G, Kalia YN, Delgado-Charro MB, Guy RH. 2000. Mechanism of enhanced transdermal transport by low-frequency sonophoresis. The role of local heating? Proceed Intl Symp Controlled Release Bioact Mater 27:942-943.
64. Merino G, Kalia YN, Delgado-Charro MB, Potts RO, Guy RH. Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis. J Controlled Release, in press.
65. Tezel A, Sens A, Tuchscherer J, Mitragotri S. 2001. Frequency dependence of sonophoresis. Pharm Res 18:1694-1700.
66. Henry S, McAllister DV, Allen MG, Prausnitz MR. 1998. Microfabricated microneedles: A novel approach to transdermal drug delivery. J Pharm Sci 87:922-925.
67. Treffel P, Gabard B. 1996. Measurement of sodium lauryl sulfate-induced skin irritation. Acta Derm Venereol 76:341-343.
68. Aramaki J, Loffler C, Kawana S, Effendy I, Happle R, Loffler H. 2001. Irritant patch testing with sodium lauryl sulphate: Interrelation between concentration and exposure time. Br J Dermatol 145:704-708.
69. Rao G, Glikfeld P, Guy RH. 1993. Reverse iontophoresis: Development of a noninvasive approach for glucose monitoring. Pharm Res 10:1751-1755.