Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin

Journal of Controlled Release

Volumn 117, Issue 2, 2007, Pages 238-245

  Verbaan, F J ^a   Bal, S M ^a   van den Berg, D J ^a   Groenink, W H H ^a   Verpoorten, H ^a   Luttge R ^b   Bouwstra, J A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Macromolecules; Microneedles; Skin; Transdermal drug delivery

Indexed keywords

CONTROLLED DRUG DELIVERY; DERMATITIS; MACROMOLECULES; MICROSTRUCTURE; MOLECULAR WEIGHT; SKIN;

MICRONEEDLE ARRAYS; MICRONEEDLES; TRANSDERMAL DRUG DELIVERY;

ARRAYS;

BLUE DEXTRAN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; TRYPAN BLUE;

ADULT; ARTICLE; CONTROLLED STUDY; DEGRADATION; DERMATOME; DIFFUSION; DRUG DELIVERY SYSTEM; FEASIBILITY STUDY; HUMAN; IN VITRO STUDY; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; NEEDLE; PASSIVE TRANSPORT; PRIORITY JOURNAL; SKIN WATER LOSS; STAINING;

ADMINISTRATION, CUTANEOUS; ADULT; DEXTRANS; DRUG DELIVERY SYSTEMS; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; MICROINJECTIONS; MOLECULAR WEIGHT; NEEDLES; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SKIN; SKIN ABSORPTION; TRYPAN BLUE; WATER;

EID: 33846542514     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.11.009     Document Type: Article

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