Lithiation of N-alkyl-(o-tolyl)aziridine: Stereoselective synthesis of isochromans

Journal of Organic Chemistry

Volumn 74, Issue 16, 2009, Pages 6319-6322

  Dammacco, Mariangela ^a   Degennaro, Leonardo ^a   Florio, Saverio ^a   Luisi, Renzo ^a   Musio, Biagia ^a   Altomare, Angela ^b  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AZIRIDINE RING; AZIRIDINES; CHEMICAL EQUATIONS; ELECTROPHILES; FUNCTIONALIZED; LITHIATION; LITHIATION REACTION; METALATIONS; STEREOSELECTIVE PREPARATION; STEREOSELECTIVE SYNTHESIS;

CHEMICAL REACTIONS; STEREOCHEMISTRY; STEREOSELECTIVITY;

IONIC LIQUIDS;

1 METHYLAMINOMETHYL 3,3 DIPHENYL 3,4 DIHYDRO 1H ISOCHROMENE; 2 (2 DEUTERIOMETHYLPHENYL) 1 METHYLAZIRIDINE; 2 [2 (1 METHYLAZIRIDIN 2 YL)PHENYL] 1,1 DIPHENYLETHANOL; AZIRIDINE DERIVATIVE; ELECTROPHILE; ISOCHROMAN DERIVATIVE; LITHIUM DERIVATIVE; UNCLASSIFIED DRUG; AZIRIDINE; CHROMAN DERIVATIVE; LITHIUM;

ARTICLE; LITHIATION; STEREOCHEMISTRY; SYNTHESIS; ALKYLATION; CHEMISTRY; STEREOISOMERISM;

ALKYLATION; AZIRIDINES; CHROMANS; LITHIUM; STEREOISOMERISM;

EID: 70349115204     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9011943     Document Type: Article

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50. The absolute configuration could be assigned considering that the intramolecular cyclization is highly stereospecific (see infra).