Quantitative structure-activity relationship studies on 2-amino-6-arylsulfonylbenzonitriles as human immunodeficiency viruses type 1 reverse transcriptase inhibitors using descriptors obtained from substituents and whole molecular structures

Chemical Biology and Drug Design

Volumn 74, Issue 4, 2009, Pages 405-415

  Hemmateenejad, Bahram ^a,b   Sabet, Razieh ^b,c,d   Fassihi, Afshin ^c,d  

^a SHIRAZ UNIVERSITY   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d Isfahan Pharmaceutical Sciences Research Center   (Iran)

Author keywords

Arylsulfonylbenzonitriles; HIV 1 reverse transcriptase; Quantitative structure activity relationship; Substituent electronic descriptors

Indexed keywords

BENZONITRILE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ANTI-HIV AGENTS; HIV REVERSE TRANSCRIPTASE; HUMANS; LEAST-SQUARES ANALYSIS; LINEAR MODELS; MODELS, CHEMICAL; NITRILES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REVERSE TRANSCRIPTASE INHIBITORS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 70349107717     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00871.x     Document Type: Article

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