-
1
-
-
0025014499
-
Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
-
Pauwels, R.; Andries, K.; Desmyter, J.; Schols, D.; Kukla, M. J. Breslin, H. J.; Raeymaechers, A.; Gelder, J. V.; Woestenborgs, R.; Heykants, J.; Schellekens, K.; Janessen, M. A. C.; De Clercq, E.; Janssen, P. A. J. Potent and Selective Inhibition of HIV-1 Replication in vitro by a Novel Series of TIBO Derivatives. Nature 1990, 343, 470-474.
-
(1990)
Nature
, vol.343
, pp. 470-474
-
-
Pauwels, R.1
Andries, K.2
Desmyter, J.3
Schols, D.4
Kukla, M.J.5
Breslin, H.J.6
Raeymaechers, A.7
Gelder, J.V.8
Woestenborgs, R.9
Heykants, J.10
Schellekens, K.11
Janessen, M.A.C.12
De Clercq, E.13
Janssen, P.A.J.14
-
2
-
-
0032741707
-
Quantitative structure-activity relationships and comparative molecular field analysis of TIBO derivatised HIV-1 reverse transcriptase inhibitors
-
Hannongbua, S.; Pungpo, P.; Limtrakul, J.; Wolschann, P. Quantitative Structure-Activity Relationships and Comparative Molecular Field Analysis of TIBO Derivatised HIV-1 Reverse Transcriptase Inhibitors. J. Comput.-Aided. Mol. Des. 1999, 13, 563-577.
-
(1999)
J. Comput.-Aided. Mol. Des.
, vol.13
, pp. 563-577
-
-
Hannongbua, S.1
Pungpo, P.2
Limtrakul, J.3
Wolschann, P.4
-
3
-
-
0033491040
-
Comparative molecular field analysis (CoMFA) and docking studies of nonnucleoside HIV-1 RT inhibitors
-
Barreca, M. L.; Carotti, A.; Carrieri, A.; Chimirri, A.; Monforte, A. M.; Calace, M. P.; Rao, A. Comparative Molecular Field Analysis (CoMFA) and Docking Studies of Nonnucleoside HIV-1 RT Inhibitors. Bioorg. Med. Chem. 1999, 7, 2283-2292.
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 2283-2292
-
-
Barreca, M.L.1
Carotti, A.2
Carrieri, A.3
Chimirri, A.4
Monforte, A.M.5
Calace, M.P.6
Rao, A.7
-
4
-
-
0030596068
-
Crystal structure of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant
-
Das, K.; Ding, J.; Hsiou, Y.; Clark Jr., A. D.; Moereels, H.; Koymans, L.; Andries, K.; Pauwels, R,; Janssen, R. A. J.; Boyer, P. L.; Clark, P.; Smith Jr., R. H.; Smith, M. B. K.; Michejda, C. J.; Hughes, S. H.; Arnold, E. Crystal Structure of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant. J. Mol. Biol. 1996, 264, 1085-1100.
-
(1996)
J. Mol. Biol.
, vol.264
, pp. 1085-1100
-
-
Das, K.1
Ding, J.2
Hsiou, Y.3
Clark Jr., A.D.4
Moereels, H.5
Koymans, L.6
Andries, K.7
Pauwels, R.8
Janssen, R.A.J.9
Boyer, P.L.10
Clark, P.11
Smith Jr., R.H.12
Smith, M.B.K.13
Michejda, C.J.14
Hughes, S.H.15
Arnold, E.16
-
5
-
-
0028172345
-
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transciptase. implications for mechanisms of drug inhibition and resistance
-
Tantillo, C.; Ding, J.; Jacobo-Molina, A.; Nanni, R. G.; Boyer, P. L.; Hughes, S. H.; Pauwels, R.; Andries, K.; Janssen, P. A. J.; Arnold, E. Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse Transciptase. Implications for Mechanisms of Drug Inhibition and Resistance. J. Mol. Biol. 1994, 243, 369-387.
-
(1994)
J. Mol. Biol.
, vol.243
, pp. 369-387
-
-
Tantillo, C.1
Ding, J.2
Jacobo-Molina, A.3
Nanni, R.G.4
Boyer, P.L.5
Hughes, S.H.6
Pauwels, R.7
Andries, K.8
Janssen, P.A.J.9
Arnold, E.10
-
6
-
-
0030900210
-
Neural network modeling for estimation of aqueous solubility of structurally related drugs
-
Huuskonen, J.; Salo, M.; Taskinen, J. Neural Network Modeling for Estimation of Aqueous Solubility of Structurally Related Drugs. J. Pharm. Sci. 1997, 86, 450-454.
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 450-454
-
-
Huuskonen, J.1
Salo, M.2
Taskinen, J.3
-
7
-
-
0029963792
-
Atom level electrotopological state indices in QSAR: Design and testing antithyroid agents
-
Abou-Shaaban, R. R.; al-Khamees, H. A.; Abou-Auda, H. S.; Simonelli, A. P. Atom Level Electrotopological State Indices in QSAR: Design and Testing Antithyroid Agents. Pharm. Res. 1996, 13, 129-136.
-
(1996)
Pharm. Res.
, vol.13
, pp. 129-136
-
-
Abou-Shaaban, R.R.1
Al-Khamees, H.A.2
Abou-Auda, H.S.3
Simonelli, A.P.4
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