Holographic enzyme inhibition assays for drug discovery

Analytical Chemistry

Volumn 81, Issue 18, 2009, Pages 7579-7589

  Eu, Vian Tan ^a   Lowe, Christopher R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; BIOMOLECULAR INTERACTIONS; DRUG DISCOVERY; FUNCTIONAL PROPERTIES; HIGH-THROUGHPUT SCREENING; HOLOGRAPHIC SENSORS; HYDROGEL FILMS; IN-SITU; IN-VITRO; LABEL-FREE DETECTION; PH CHANGE; PH-RESPONSIVE; REFLECTION HOLOGRAM; SCREENING METHODS; SINGLE SENSOR; STORAGE STABILITY;

ASSAYS; CHEMICAL MODIFICATION; DRUG INTERACTIONS; ENZYMES; OPTICAL PROPERTIES; OPTICAL SENSORS; SENSORS;

ENZYME INHIBITION;

ACETIC ACID; ACETYLCHOLINE; ACETYLCHOLINESTERASE; EDROPHONIUM; GALANTAMINE; NEOSTIGMINE; PHYSOSTIGMINE; TACRINE;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG RESEARCH; ENZYME ASSAY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HOLOGRAPHIC ENZYME INHIBITION ASSAY; HOLOGRAPHY; HYDROGEL; MOLECULAR SENSOR; PH MEASUREMENT;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; DRUG DISCOVERY; ENZYMES, IMMOBILIZED; FLUORESCENT DYES; HOLOGRAPHY; HYDROGEL; HYDROGEN-ION CONCENTRATION;

EID: 70349099635     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9008989     Document Type: Article

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