Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-κB modulates glucocorticoid receptor and NF-κB signalling in HEK-293 cells

Biochemical Journal

Volumn 422, Issue 3, 2009, Pages 521-531

  Psarra, Anna Maria G ^a   Hermann, Stefan ^a,c   Panayotou, George ^b   Spyrou, Giannis ^a  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^c Glucometrix   (Germany)

Author keywords

Glucocorticoid receptor (GR); Mitochondria; Nuclear factor B (NF B); Reactive oxygen species (ROS); Thioredoxin; Transcription

Indexed keywords

293 CELLS; ANTI-APOPTOTIC FACTOR; APOPTOSIS; CELL VIABILITY; CYTOCHROME B; CYTOCHROME OXIDASE; DEXAMETHASONES; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR (GR); HEK293 CELLS; HUMAN EMBRYONIC KIDNEYS; MITOCHONDRIAL TRANSCRIPTION; MRNA LEVEL; NECROSIS FACTORS; NUCLEAR FACTORS; OVER-EXPRESSION; REACTIVE OXYGEN SPECIES (ROS); REDOX CONDITION; REPORTER GENE; SIGNALLING PATHWAYS; SPR (SURFACE PLASMON RESONANCE); THIOREDOXIN; THIOREDOXINS;

ACTIVATION ANALYSIS; CELL CULTURE; CELL DEATH; CELL MEMBRANES; LAWS AND LEGISLATION; MITOCHONDRIA; OXYGEN; SURFACE PLASMON RESONANCE; TRANSCRIPTION FACTORS; TUMORS;

TRANSCRIPTION;

CYTOCHROME B; CYTOCHROME C OXIDASE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; THIOREDOXIN REDUCTASE 1; THIOREDOXIN REDUCTASE 2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; CYCLOOXYGENASE 1; GLUCOCORTICOID; MITOCHONDRIAL PROTEIN; PTGS1 PROTEIN, HUMAN; TXN2 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; EMBRYO; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; TRANSCRIPTION REGULATION; CELL LINE; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN BINDING;

CELL LINE; CYCLOOXYGENASE 1; CYTOCHROMES B; DEXAMETHASONE; GENE EXPRESSION; GLUCOCORTICOIDS; HUMANS; IMMUNOPRECIPITATION; MITOCHONDRIAL PROTEINS; NF-KAPPA B; POLYMERASE CHAIN REACTION; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; THIOREDOXINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70249089081     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090107     Document Type: Article

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