메뉴 건너뛰기




Volumn 100, Issue 9, 2009, Pages 1740-1747

Effect of the alcoholic extract of Ashwagandha leaves and its components on proliferation, migration, and differentiation of glioblastoma cells: Combinational approach for enhanced differentiation

Author keywords

[No Author keywords available]

Indexed keywords

3 RHAMNOPYRANOSYL(1 4) GLUCOPYRANOSYL 12 DIACETOXY 20 HYDROXYWITHA 5,24 DIENOLIDE; 3-RHAMNOPYRANOSYL(1-4)-GLUCOPYRANOSYL-12-DIACETOXY-20-HYDROXYWITHA-5,24-DIENOLIDE; DRUG DERIVATIVE; ERGOSTEROL; PLANT EXTRACT; WITHAFERIN A;

EID: 70149089441     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01236.x     Document Type: Article
Times cited : (91)

References (60)
  • 1
    • 0012913831 scopus 로고
    • A review of work on Indian Medicinal plants
    • Indian Council of Medical Research. Cambridge Printing Works, Kashmere Gate, New Delhi
    • Chopra RN. A review of work on Indian Medicinal plants. In Pharmacopoeia of India Indian Council of Medical Research. Cambridge Printing Works, Kashmere Gate, New Delhi, 1955.
    • (1955) In: Pharmacopoeia of India
    • Chopra, R.N.1
  • 2
    • 0032788630 scopus 로고    scopus 로고
    • Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation
    • Agarwal R, Diwanay S, Patki P, Patwardhan B. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. J Ethnopharmacol 1999; 67: 27-35.
    • (1999) J Ethnopharmacol , vol.67 , pp. 27-35
    • Agarwal, R.1    Diwanay, S.2    Patki, P.3    Patwardhan, B.4
  • 3
    • 0033845752 scopus 로고    scopus 로고
    • Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review
    • Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000; 5: 334-46.
    • (2000) Altern Med Rev , vol.5 , pp. 334-346
    • Mishra, L.C.1    Singh, B.B.2    Dagenais, S.3
  • 4
    • 0033918062 scopus 로고    scopus 로고
    • Review on some plants of Indian traditional medicine with antioxidant activity
    • Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J Ethnopharmacol 2000; 71: 23-43.
    • (2000) J Ethnopharmacol , vol.71 , pp. 23-43
    • Scartezzini, P.1    Speroni, E.2
  • 5
    • 0034717794 scopus 로고    scopus 로고
    • Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells
    • Tohda C, Kuboyama T, Komatsu K. Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells. Neuroreport 2000; 11: 1981-5.
    • (2000) Neuroreport , vol.11 , pp. 1981-1985
    • Tohda, C.1    Kuboyama, T.2    Komatsu, K.3
  • 6
    • 0036990430 scopus 로고    scopus 로고
    • Effect of Withania somnifera on cell mediated immune responses in mice
    • Davis L, Kuttan G. Effect of Withania somnifera on cell mediated immune responses in mice. J Exp Clin Cancer Res 2002; 21: 585-90.
    • (2002) J Exp Clin Cancer Res , vol.21 , pp. 585-590
    • Davis, L.1    Kuttan, G.2
  • 7
    • 17844363245 scopus 로고    scopus 로고
    • Neuritic regeneration and synaptic reconstruction induced by withanolide A
    • Kuboyama T, Tohda C, Komatsu K. Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol 2005; 144: 961-71.
    • (2005) Br J Pharmacol , vol.144 , pp. 961-971
    • Kuboyama, T.1    Tohda, C.2    Komatsu, K.3
  • 8
    • 0041696950 scopus 로고    scopus 로고
    • Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress.
    • Bhattacharya SK, Muruganandam AV. Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol Biochem Behav 2003; 75: 547-55.
    • (2003) Pharmacol Biochem Behav , vol.75 , pp. 547-555
    • Bhattacharya, S.K.1    Muruganandam, A.V.2
  • 9
    • 0345601897 scopus 로고    scopus 로고
    • Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidative modifications
    • Gupta SK, Dua A, Vohra BP. Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidative modifications. Drug Metabol Drug Interact 2003; 19: 211-22.
    • (2003) Drug Metabol Drug Interact , vol.19 , pp. 211-222
    • Gupta, S.K.1    Dua, A.2    Vohra, B.P.3
  • 10
    • 0038526374 scopus 로고    scopus 로고
    • Adaptogenic activity of a novel withanolide-free aqueous fraction from the roots of Withania somnifera Dun.(Part II)
    • Singh B, Chandan BK, Gupta DK. Adaptogenic activity of a novel withanolide-free aqueous fraction from the roots of Withania somnifera Dun.(Part II).Phytother Res 2003;17: 531-6
    • (2003) Phytother Res , vol.17 , pp. 531-536
    • Singh, B.1    Chandan, B.K.2    Gupta, D.K.3
  • 11
    • 34247536630 scopus 로고    scopus 로고
    • Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect
    • Widodo N, Kaur K, Shrestha BG et al. Selective killing of cancer cells by leaf extract of Ashwagandha: identification of a tumor-inhibitory factor and the first molecular insights to its effect. Clin Cancer Res 2007; 13: 2298-306.
    • (2007) Clin Cancer Res , vol.13 , pp. 2298-2306
    • Widodo, N.1    Kaur, K.2    Shrestha, B.G.3
  • 12
    • 42449099302 scopus 로고    scopus 로고
    • Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses
    • Widodo N, Takagi Y, Shrestha BG, Ishii T, Kaul SC, Wadhwa R. Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses. Cancer Lett 2008; 262: 37-47.
    • (2008) Cancer Lett , vol.262 , pp. 37-47
    • Widodo, N.1    Takagi, Y.2    Shrestha, B.G.3    Ishii, T.4    Kaul, S.C.5    Wadhwa, R.6
  • 13
    • 0034805009 scopus 로고    scopus 로고
    • Nootropic-like effect of ashwagandha (Withania somnifera L)
    • Dhuley JN. Nootropic-like effect of ashwagandha (Withania somnifera L.) in mice. Phytother Res 2001; 15: 524-8.
    • (2001) in mice. Phytother Res , vol.15 , pp. 524-528
    • Dhuley, J.N.1
  • 14
    • 33645108007 scopus 로고    scopus 로고
    • Withanoside IV and its active metabolite, sominone, attenuate Abeta (25-35)-induced neurodegeneration
    • Kuboyama T, Tohda C, Komatsu K. Withanoside IV and its active metabolite, sominone, attenuate Abeta (25-35)-induced neurodegeneration. Eur J Neurosci 2006; 23: 1417-26.
    • (2006) Eur J Neurosci , vol.23 , pp. 1417-1426
    • Kuboyama, T.1    Tohda, C.2    Komatsu, K.3
  • 15
    • 9644262477 scopus 로고    scopus 로고
    • Evaluation of the antigenotoxicity of leaf extract of Ashwagandha.
    • Rani G, Kaur K, Wadhwa R, Kaul SC, Nagpal A. Evaluation of the antigenotoxicity of leaf extract of Ashwagandha. Food Chem Toxicol 2005; 43: 95-8.
    • (2005) Food Chem Toxicol , vol.43 , pp. 95-98
    • Rani, G.1    Kaur, K.2    Wadhwa, R.3    Kaul, S.C.4    Nagpal, A.5
  • 16
    • 7044220551 scopus 로고    scopus 로고
    • Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha
    • Kaur K, Rani G, Widodo N et al. Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha. Food Chem Toxicol 2004; 42: 2015-20.
    • (2004) Food Chem Toxicol , vol.42 , pp. 2015-2020
    • Kaur, K.1    Rani, G.2    Widodo, N.3
  • 17
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989; 119: 203-10.
    • (1989) J Immunol Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, S.E.2    Berg, K.3
  • 18
    • 0027227379 scopus 로고
    • Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts
    • Wadhwa R, Kaul SC, Mitsui Y, Sugimoto Y. Differential subcellular distribution of mortalin in mortal and immortal mouse and human fibroblasts. Exp Cell Res 1993; 207: 442-8.
    • (1993) Exp Cell Res , vol.207 , pp. 442-448
    • Wadhwa, R.1    Kaul, S.C.2    Mitsui, Y.3    Sugimoto, Y.4
  • 19
    • 0024457263 scopus 로고
    • Growth factors produced by rat glioma cells: activities of transforming growth factors
    • Kanno H, Shinonaga M, Kuwabara T, Umeda M. [Growth factors produced by rat glioma cells: activities of transforming growth factors]. No To Shinkei 1989 ;41:905-9.
    • (1989) No To Shinkei , vol.41 , pp. 905-909
    • Kanno, H.1    Shinonaga, M.2    Kuwabara, T.3    Umeda, M.4
  • 20
    • 0034671731 scopus 로고    scopus 로고
    • Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function
    • Wadhwa R, Sugihara T, Yoshida A et al. Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function. Cancer Res 2000; 60: 6818-21.
    • (2000) Cancer Res , vol.60 , pp. 6818-6821
    • Wadhwa, R.1    Sugihara, T.2    Yoshida, A.3
  • 21
    • 0033381225 scopus 로고    scopus 로고
    • 5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species
    • Michishita E, Nakabayashi K, Suzuki T et al. 5-Bromodeoxyuridine induces senescence-like phenomena in mammalian cells regardless of cell type or species. J Biochem 1999; 126: 1052-9.
    • (1999) J Biochem , vol.126 , pp. 1052-1059
    • Michishita, E.1    Nakabayashi, K.2    Suzuki, T.3
  • 22
    • 34249291074 scopus 로고    scopus 로고
    • Mortalin sensitizes human cancer cells to MKT-077-induced senescence
    • Deocaris CC, Widodo N, Shrestha BG et al. Mortalin sensitizes human cancer cells to MKT-077-induced senescence. Cancer Lett 2007; 252: 259-69.
    • (2007) Cancer Lett , vol.252 , pp. 259-269
    • Deocaris, C.C.1    Widodo, N.2    Shrestha, B.G.3
  • 23
    • 0036791842 scopus 로고    scopus 로고
    • Mortalin: a potential candidate for biotechnology and biomedicine
    • Wadhwa R, Taira K, Kaul SC. Mortalin: a potential candidate for biotechnology and biomedicine. Histol Histopathol 2002; 17: 1173-7.
    • (2002) Histol Histopathol , vol.17 , pp. 1173-1177
    • Wadhwa, R.1    Taira, K.2    Kaul, S.C.3
  • 24
    • 0036682377 scopus 로고    scopus 로고
    • Rhodacyanine dye MKT-077 inhibits in vitro telomerase assay but has no detectable effects on telomerase activity in vivo
    • Wadhwa R, Colgin L, Yaguchi T, Taira K, Reddel RR, Kaul SC. Rhodacyanine dye MKT-077 inhibits in vitro telomerase assay but has no detectable effects on telomerase activity in vivo. Cancer Res 2002; 62: 4434-8.
    • (2002) Cancer Res , vol.62 , pp. 4434-4438
    • Wadhwa, R.1    Colgin, L.2    Yaguchi, T.3    Taira, K.4    Reddel, R.R.5    Kaul, S.C.6
  • 25
    • 34447307977 scopus 로고    scopus 로고
    • Mortalin is a novel mediator of erythropoietin signaling
    • Ohtsuka R, Abe Y, Fujii T et al. Mortalin is a novel mediator of erythropoietin signaling. Eur J Haematol 2007; 79: 114-25.
    • (2007) Eur J Haematol , vol.79 , pp. 114-125
    • Ohtsuka, R.1    Abe, Y.2    Fujii, T.3
  • 26
    • 65249169355 scopus 로고    scopus 로고
    • Immune modulation and apoptosis induction: two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera
    • Malik F, Kumar A, Bhushan S et al. Immune modulation and apoptosis induction: two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera. Eur J Cancer 2009; 45: 1494-509.
    • (2009) Eur J Cancer , vol.45 , pp. 1494-1509
    • Malik, F.1    Kumar, A.2    Bhushan, S.3
  • 27
    • 34848858255 scopus 로고    scopus 로고
    • Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine
    • Malik F, Kumar A, Bhushan S et al. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine. Apoptosis 2007; 12: 2115-33.
    • (2007) Apoptosis , vol.12 , pp. 2115-2133
    • Malik, F.1    Kumar, A.2    Bhushan, S.3
  • 28
    • 77950853664 scopus 로고    scopus 로고
    • Genomic analysis highlights the role of the JAK-STAT signaling in the anti-proliferative effects of dietary flavonoid 'Ashwagandha' in prostate cancer cells
    • Aalinkeel R, Hu Z, Nair BB et al. Genomic analysis highlights the role of the JAK-STAT signaling in the anti-proliferative effects of dietary flavonoid 'Ashwagandha' in prostate cancer cells. Evid Based Complement Alternat Med 2008.
    • (2008) Evid Based Complement Alternat Med
    • Aalinkeel, R.1    Hu, Z.2    Nair, B.B.3
  • 29
    • 0347753599 scopus 로고    scopus 로고
    • Immunoprotection by botanical drugs in cancer chemotherapy
    • Diwanay S, Chitre D, Patwardhan B. Immunoprotection by botanical drugs in cancer chemotherapy. J Ethnopharmacol 2004; 90: 49-55.
    • (2004) J Ethnopharmacol , vol.90 , pp. 49-55
    • Diwanay, S.1    Chitre, D.2    Patwardhan, B.3
  • 30
    • 3242670823 scopus 로고    scopus 로고
    • Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma
    • Christina AJ, Joseph DG, Packialakshmi M et al. Anticarcinogenic activity of Withania somnifera Dunal against Dalton's ascitic lymphoma. J Ethnopharmacol 2004; 93: 359-61.
    • (2004) J Ethnopharmacol , vol.93 , pp. 359-361
    • Christina, A.J.1    Joseph, D.G.2    Packialakshmi, M.3
  • 31
    • 0029759225 scopus 로고    scopus 로고
    • Use of Withania somnifera Dunal as an adjuvant during radiation therapy
    • Kuttan G. Use of Withania somnifera Dunal as an adjuvant during radiation therapy. Indian J Exp Biol 1996; 34: 854-6.
    • (1996) Indian J Exp Biol , vol.34 , pp. 854-856
    • Kuttan, G.1
  • 32
    • 1642344588 scopus 로고    scopus 로고
    • Effect of Withania somnifera on B16F-10 melanoma induced metastasis in mice
    • Leyon PV, Kuttan G. Effect of Withania somnifera on B16F-10 melanoma induced metastasis in mice. Phytother Res 2004; 18: 118-22.
    • (2004) Phytother Res , vol.18 , pp. 118-122
    • Leyon, P.V.1    Kuttan, G.2
  • 33
    • 0028264312 scopus 로고
    • Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells
    • Rutka JT, Hubbard SL, Fukuyama K, Matsuzawa K, Dirks PB, Becker LE. Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells. Cancer Res 1994; 54: 3267-72.
    • (1994) Cancer Res , vol.54 , pp. 3267-3272
    • Rutka, J.T.1    Hubbard, S.L.2    Fukuyama, K.3    Matsuzawa, K.4    Dirks, P.B.5    Becker, L.E.6
  • 34
    • 0032498333 scopus 로고    scopus 로고
    • Overexpression of p21WAF1/CIP1 induces cell differentiation and growth inhibition in a human glioma cell line
    • Kokunai T, Izawa I, Tamaki N. Overexpression of p21WAF1/CIP1 induces cell differentiation and growth inhibition in a human glioma cell line. Int J Cancer 1998; 75: 643-8.
    • (1998) Int J Cancer , vol.75 , pp. 643-648
    • Kokunai, T.1    Izawa, I.2    Tamaki, N.3
  • 35
    • 48949099555 scopus 로고    scopus 로고
    • N-(4-Hydroxyphenyl) retinamide induced both differentiation and apoptosis in human glioblastoma T98G and U87MG cells
    • Das A, Banik NL, Ray SK. N-(4-Hydroxyphenyl) retinamide induced both differentiation and apoptosis in human glioblastoma T98G and U87MG cells. Brain Res 2008; 1227: 207-15.
    • (2008) Brain Res , vol.1227 , pp. 207-215
    • Das, A.1    Banik, N.L.2    Ray, S.K.3
  • 36
    • 0031572306 scopus 로고    scopus 로고
    • Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1
    • Nakabayashi K, Ogata T, Fujii M et al. Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1. Exp Cell Res 1997; 235: 345-53.
    • (1997) Exp Cell Res , vol.235 , pp. 345-353
    • Nakabayashi, K.1    Ogata, T.2    Fujii, M.3
  • 37
    • 0345654336 scopus 로고    scopus 로고
    • Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes
    • Bertram MJ, Berube NG, Hang-Swanson X et al. Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. Mol Cell Biol 1999; 19: 1479-85.
    • (1999) Mol Cell Biol , vol.19 , pp. 1479-1485
    • Bertram, M.J.1    Berube, N.G.2    Hang-Swanson, X.3
  • 38
    • 0029126681 scopus 로고
    • Inhibitors of cGMP-dependent protein kinase block senescence induced by inactivation of T antigen in SV40-transformed immortal human fibroblasts
    • Fujii M, Ide T, Wadhwa R, Tahara H et al. Inhibitors of cGMP-dependent protein kinase block senescence induced by inactivation of T antigen in SV40-transformed immortal human fibroblasts. Oncogene 1995; 11: 627-34.
    • (1995) Oncogene , vol.11 , pp. 627-634
    • Fujii, M.1    Ide, T.2    Wadhwa, R.3    Tahara, H.4
  • 39
    • 12644286553 scopus 로고    scopus 로고
    • Cell signalling and CAM-mediated neurite outgrowth
    • Walsh FS, Meiri K, Doherty P. Cell signalling and CAM-mediated neurite outgrowth. Soc Gen Physiol Ser 1997; 52: 221-6.
    • (1997) Soc Gen Physiol Ser , vol.52 , pp. 221-226
    • Walsh, F.S.1    Meiri, K.2    Doherty, P.3
  • 41
    • 13244290151 scopus 로고    scopus 로고
    • Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion
    • Suzuki T, Izumoto S, Fujimoto Y, Maruno M, Ito Y, Yoshimine T. Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion. J Clin Pathol 2005; 58: 166-71.
    • (2005) J Clin Pathol , vol.58 , pp. 166-171
    • Suzuki, T.1    Izumoto, S.2    Fujimoto, Y.3    Maruno, M.4    Ito, Y.5    Yoshimine, T.6
  • 42
    • 0034657697 scopus 로고    scopus 로고
    • N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype
    • Amoureux MC, Cunningham BA, Edelman GM, Crossin KL. N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype. J Neurosci 2000; 20: 3631-40.
    • (2000) J Neurosci , vol.20 , pp. 3631-3640
    • Amoureux, M.C.1    Cunningham, B.A.2    Edelman, G.M.3    Crossin, K.L.4
  • 43
    • 0032478335 scopus 로고    scopus 로고
    • Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation
    • Krushel LA, Tai MH, Cunningham BA, Edelman GM, Crossin KL. Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation. Proc Natl Acad Sci USA 1998; 95: 2592-6.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2592-2596
    • Krushel, L.A.1    Tai, M.H.2    Cunningham, B.A.3    Edelman, G.M.4    Crossin, K.L.5
  • 44
    • 22244490629 scopus 로고    scopus 로고
    • Retrovirally transduced NCAM140 facilitates neuronal fate choice of hippocampal progenitor cells
    • Kim JH, Lee JH, Park JY et al. Retrovirally transduced NCAM140 facilitates neuronal fate choice of hippocampal progenitor cells. J Neurochem 2005; 94: 417-24.
    • (2005) J Neurochem , vol.94 , pp. 417-424
    • Kim, J.H.1    Lee, J.H.2    Park, J.Y.3
  • 48
    • 0026053853 scopus 로고
    • Characterization of NCAM expression and function in BT4C and BT4Cn glioma cells
    • Andersson AM, Moran N, Gaardsvoll H et al. Characterization of NCAM expression and function in BT4C and BT4Cn glioma cells. Int J Cancer
    • (1991) Int J Cancer , vol.47 , pp. 124-129
    • Andersson, A.M.1    Moran, N.2    Gaardsvoll, H.3
  • 49
    • 58149157945 scopus 로고    scopus 로고
    • Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis
    • Hsu WM, Lee H, Juan HF et al. Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis. Clin Cancer Res 2008; 14: 6237-45.
    • (2008) Clin Cancer Res , vol.14 , pp. 6237-6245
    • Hsu, W.M.1    Lee, H.2    Juan, H.F.3
  • 51
    • 35848955916 scopus 로고    scopus 로고
    • Emerging role of combination of all-trans retinoic acid and interferon-gamma as chemoimmunotherapy in the management of human glioblastoma
    • Haque A, Banik NL, Ray SK. Emerging role of combination of all-trans retinoic acid and interferon-gamma as chemoimmunotherapy in the management of human glioblastoma. Neurochem Res 2007; 32: 2203-9.
    • (2007) Neurochem Res , vol.32 , pp. 2203-2209
    • Haque, A.1    Banik, N.L.2    Ray, S.K.3
  • 52
    • 45749115404 scopus 로고    scopus 로고
    • Combination of all-trans retinoic acid and interferon-gamma upregulated p27 (kip1) and downregulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells
    • Zhang R, Banik NL, Ray SK. Combination of all-trans retinoic acid and interferon-gamma upregulated p27 (kip1) and downregulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells. Cancer Chemother Pharmacol 2008; 62: 407-16.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 407-416
    • Zhang, R.1    Banik, N.L.2    Ray, S.K.3
  • 53
    • 38649083441 scopus 로고    scopus 로고
    • Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells
    • Das A, Banik NL, Ray SK. Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells. J Neurooncol 2008; 87: 9-22.
    • (2008) J Neurooncol , vol.87 , pp. 9-22
    • Das, A.1    Banik, N.L.2    Ray, S.K.3
  • 54
    • 38749131581 scopus 로고    scopus 로고
    • Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice
    • Karmakar S, Banik NL, Ray SK. Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer 2008; 112: 596-607.
    • (2008) Cancer , vol.112 , pp. 596-607
    • Karmakar, S.1    Banik, N.L.2    Ray, S.K.3
  • 55
    • 0033074481 scopus 로고    scopus 로고
    • High throughput system for the evaluation of protein kinase C inhibitors based on Elk1 transcriptional activation in human astrocytoma cells
    • Sharif TR, Sharif MA. High throughput system for the evaluation of protein kinase C inhibitors based on Elk1 transcriptional activation in human astrocytoma cells. Int J Oncol 1999; 14: 327-35.
    • (1999) Int J Oncol , vol.14 , pp. 327-335
    • Sharif, T.R.1    Sharif, M.A.2
  • 56
    • 0033655188 scopus 로고    scopus 로고
    • Human malignant glioma cell lines are refractory to retinoic acid-mediated differentiation and sensitization to apoptosis
    • Schmidt F, Groscurth P, Dichgans J, Weller M. Human malignant glioma cell lines are refractory to retinoic acid-mediated differentiation and sensitization to apoptosis. Cell Physiol Biochem 2000; 10: 159-68.
    • (2000) Cell Physiol Biochem , vol.10 , pp. 159-168
    • Schmidt, F.1    Groscurth, P.2    Dichgans, J.3    Weller, M.4
  • 58
    • 44449130430 scopus 로고    scopus 로고
    • Growth inhibition and induction of differentiation by panaxydol in rat C6 glioma cells
    • Hai J, Lin Q, Lu Y, Yi J, Zhang H. Growth inhibition and induction of differentiation by panaxydol in rat C6 glioma cells. Neurol Res 2008; 30: 99-105.
    • (2008) Neurol Res , vol.30 , pp. 99-105
    • Hai, J.1    Lin, Q.2    Lu, Y.3    Yi, J.4    Zhang, H.5
  • 59
    • 34548067125 scopus 로고    scopus 로고
    • Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway
    • Li Y, Yin W, Wang X, Zhu W, Huang Y, Yan G. Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proc Natl Acad Sci USA 2007; 104: 13 438-43.
    • (2007) Proc Natl Acad Sci USA , vol.104
    • Li, Y.1    Yin, W.2    Wang, X.3    Zhu, W.4    Huang, Y.5    Yan, G.6
  • 60
    • 59349118166 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activity is required for the induction of differentiation in C6 glioma cells by panaxydol
    • Hai J, Lin Q, Lu Y. Phosphatidylinositol 3-kinase activity is required for the induction of differentiation in C6 glioma cells by panaxydol. J Clin Neurosci
    • (2009) J Clin Neurosci , vol.16 , pp. 444-448
    • Hai, J.1    Lin, Q.2    Lu, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.