A high throughput system for the evaluation of protein kinase C inhibitors based on Elk1 transcriptional activation in human astrocytoma cells

International Journal of Oncology

Volumn 14, Issue 2, 1999, Pages 327-335

  Sharif, Taraneh R ^a   Sharif, Mohammed ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Astrocytoma cell line; Elk1; GAL4; Luciferase; Mitogen activated protein kinase; Mitogens; PKC inhibitors; Protein kinase C; U 373MG

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 4'-N-BENZOYLSTAUROSPORINE; ANTINEOPLASTIC AGENT; CARBAZOLE DERIVATIVE; DNA BINDING PROTEIN; DRUG DERIVATIVE; ELK1 PROTEIN, HUMAN; ENZYME INHIBITOR; INDOLE DERIVATIVE; MIDOSTAURIN; ONCOPROTEIN; POTASSIUM CHANNEL; PROTEIN KINASE C; STAUROSPORINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1;

ARTICLE; ASTROCYTOMA; CELL CULTURE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; GENETICS; HUMAN; PATHOLOGY; TRANSACTIVATION;

ANTINEOPLASTIC AGENTS; ASTROCYTOMA; CARBAZOLES; CELL DIVISION; DNA-BINDING PROTEINS; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; ETS-DOMAIN PROTEIN ELK-1; HUMANS; INDOLES; POTASSIUM CHANNELS; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS; STAUROSPORINE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0033074481     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.14.2.327     Document Type: Article

References (12)

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