Simvastatin acts as an inhibitor of interferon gamma-induced cycloxygenase-2 expression in human THP-1 cells, but not in murine RAW264.7 cells

Biocell

Volumn 33, Issue 2, 2009, Pages 107-114

  Chang, Seok Lee ^a   Yong, Jae Shin ^a   Won, Cheolhee ^a   Lee, Yun Song ^b   Park, Chung Gyu ^a   Ye, Sang Kyu ^a   Chung, Myung Hee ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

INF ; Macrophage; Monocyte; SOCS1 3; STAT1 3

Indexed keywords

CYCLOOXYGENASE 2; GAMMA INTERFERON; SIMVASTATIN; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IMMUNOSUPPRESSIVE TREATMENT; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD86; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-GAMMA; MACROPHAGES; MICE; MODELS, BIOLOGICAL; MONOCYTES; RNA, MESSENGER; SIMVASTATIN; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

MURINAE;

EID: 69949182486     PISSN: 03279545     EISSN: 16675746     Source Type: Journal    
DOI: None     Document Type: Article

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