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Volumn 4, Issue 2, 2009, Pages 145-154

Epigenetically regulated tumor-associated antigens in melanoma

Author keywords

Cancer testis antigen; DNA methylation; Epigenetics; Histone acetylation; Immune escape; Melanoma

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CANCER TESTIS ANTIGEN; DNA METHYLTRANSFERASE; HIGH MOLECULAR WEIGHT MELANOMA ASSOCIATED ANTIGEN; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; INTERLEUKIN 2; MELANOMA ANTIGEN; NY ESO 1 ANTIGEN; PROTEOCHONDROITIN SULFATE; TRICHOSTATIN A; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VORINOSTAT;

EID: 69949178318     PISSN: 17469872     EISSN: None     Source Type: Journal    
DOI: 10.1586/edm.09.6     Document Type: Review
Times cited : (2)

References (106)
  • 2
    • 30044438884 scopus 로고    scopus 로고
    • Processing and presentation of tumor antigens and vaccination strategies
    • van der Bruggen P, Van den Eynde BJV. Processing and presentation of tumor antigens and vaccination strategies. Curr. Opin. Immunol. 18(1), 98-104 (2006).
    • (2006) Curr. Opin. Immunol , vol.18 , Issue.1 , pp. 98-104
    • van der Bruggen, P.1    Van den Eynde, B.J.V.2
  • 3
    • 2942591945 scopus 로고    scopus 로고
    • The cancer/testis genes: Review, standardization, and commentary
    • Scanlan MJ, Simpson AJ, Old LJ. The cancer/testis genes: review, standardization, and commentary. Cancer Immunol. 4, 1 (2004).
    • (2004) Cancer Immunol , vol.4 , pp. 1
    • Scanlan, M.J.1    Simpson, A.J.2    Old, L.J.3
  • 4
    • 0026322151 scopus 로고
    • A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
    • van der Bruggen P, Traversari C, Chomez P et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 254(5038), 1643-1647 (1991).
    • (1991) Science , vol.254 , Issue.5038 , pp. 1643-1647
    • van der Bruggen, P.1    Traversari, C.2    Chomez, P.3
  • 5
    • 0028298174 scopus 로고
    • Identi?cation of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection
    • Kawakami Y, Eliyahu S, Delgado CH et al. Identi?cation of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc. Natl Acad. Sci. USA 91(14), 6458-6462 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , Issue.14 , pp. 6458-6462
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3
  • 6
    • 33746211234 scopus 로고    scopus 로고
    • NY-ESO-1: Review of an immunogenic tumor antigen
    • George FV Eds, Elsevier, Academic Press, MA, USA
    • Gnjatic S, Nishikawa H, Jungbluth AA et al. NY-ESO-1: review of an immunogenic tumor antigen. In: Advances in Cancer Research. George FV (Eds). Elsevier, Academic Press, MA, USA 1-30 (2006)
    • (2006) Advances in Cancer Research , pp. 1-30
    • Gnjatic, S.1    Nishikawa, H.2    Jungbluth, A.A.3
  • 7
    • 3142617463 scopus 로고    scopus 로고
    • Humoral immunity to human breast cancer: Antigen definition and quantitative analysis of mRNA expression
    • Scanlan MJ, Gout I, Gordon CM et al. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. Cancer Immunol. 1, 4 (2001).
    • (2001) Cancer Immunol , vol.1 , pp. 4
    • Scanlan, M.J.1    Gout, I.2    Gordon, C.M.3
  • 8
    • 49149088707 scopus 로고    scopus 로고
    • Next generation of immunotherapy for melanoma
    • Kirkwood JM, Tarhini AA, Panelli MC et al. Next generation of immunotherapy for melanoma. J. Clin. Oncol. 26(20), 3445-3455 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.20 , pp. 3445-3455
    • Kirkwood, J.M.1    Tarhini, A.A.2    Panelli, M.C.3
  • 9
    • 53949089178 scopus 로고    scopus 로고
    • State of the science 60th anniversary review: 60 years of advances in cutaneous melanoma epidemiology, diagnosis, and treatment, as reported in the journal Cancer
    • Demierre MF, Sabel MS, Margolin KA, Daud AI, Sondak VK. State of the science 60th anniversary review: 60 years of advances in cutaneous melanoma epidemiology, diagnosis, and treatment, as reported in the journal Cancer. Cancer 113(7 Suppl.), 1728-1743 (2008).
    • (2008) Cancer , vol.113 , Issue.7 SUPPL. , pp. 1728-1743
    • Demierre, M.F.1    Sabel, M.S.2    Margolin, K.A.3    Daud, A.I.4    Sondak, V.K.5
  • 11
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg SA. Progress in human tumour immunology and immunotherapy. Nature 411(6835), 380-384 (2001).
    • (2001) Nature , vol.411 , Issue.6835 , pp. 380-384
    • Rosenberg, S.A.1
  • 12
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat. Med. 10(9), 909-915 (2004).
    • (2004) Nat. Med , vol.10 , Issue.9 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 13
    • 34748849509 scopus 로고    scopus 로고
    • Vaccine therapy for melanoma: Current status and future directions
    • Terando AM, Faries MB, Morton DL. Vaccine therapy for melanoma: current status and future directions. Vaccine 25(Suppl. 2), B4-B16 (2007).
    • (2007) Vaccine , vol.25 , Issue.SUPPL. 2
    • Terando, A.M.1    Faries, M.B.2    Morton, D.L.3
  • 14
    • 33845247092 scopus 로고    scopus 로고
    • Principles of cancer treatment by immunotherapy
    • Durrant LG, Scholefield JH. Principles of cancer treatment by immunotherapy. Surgery (Oxford) 24(2), 55-58 (2006).
    • (2006) Surgery (Oxford) , vol.24 , Issue.2 , pp. 55-58
    • Durrant, L.G.1    Scholefield, J.H.2
  • 15
    • 4444329501 scopus 로고    scopus 로고
    • Cancer vaccine development: On the way to break immune tolerance to malignant cells
    • Mocellin S, Rossi CR, Nitti D. Cancer vaccine development: on the way to break immune tolerance to malignant cells. Exp. Cell Res. 299(2), 267-278 (2004).
    • (2004) Exp. Cell Res , vol.299 , Issue.2 , pp. 267-278
    • Mocellin, S.1    Rossi, C.R.2    Nitti, D.3
  • 16
    • 0038069515 scopus 로고    scopus 로고
    • MHC class I antigens, immune surveillance, and tumor immune escape
    • Garcia-Lora A, Algarra I, Garrido F. MHC class I antigens, immune surveillance, and tumor immune escape. J. Cell. Physiol. 195(3), 346-355 (2003).
    • (2003) J. Cell. Physiol , vol.195 , Issue.3 , pp. 346-355
    • Garcia-Lora, A.1    Algarra, I.2    Garrido, F.3
  • 17
    • 0036157853 scopus 로고    scopus 로고
    • HLA class I antigen abnormalities and immune escape by malignant cells
    • Seliger B, Cabrera T, Garrido F, Ferrone S. HLA class I antigen abnormalities and immune escape by malignant cells. Semin. Cancer Biol. 12(1), 3-13 (2002).
    • (2002) Semin. Cancer Biol , vol.12 , Issue.1 , pp. 3-13
    • Seliger, B.1    Cabrera, T.2    Garrido, F.3    Ferrone, S.4
  • 18
    • 33846225204 scopus 로고    scopus 로고
    • Aptsiauri N, Cabrera T, Garcia-Lora A, Lopez-Nevot MA, Ruiz-Cabello F, Garrido F. MHC class I antigens and immune surveillance in transformed cells. In: International Review of Cytology A Survey of Cell Biology. Kwang WJ (Ed.). Academic Press, MA, USA 139-189 (2007).
    • Aptsiauri N, Cabrera T, Garcia-Lora A, Lopez-Nevot MA, Ruiz-Cabello F, Garrido F. MHC class I antigens and immune surveillance in transformed cells. In: International Review of Cytology A Survey of Cell Biology. Kwang WJ (Ed.). Academic Press, MA, USA 139-189 (2007).
  • 19
    • 0942276934 scopus 로고    scopus 로고
    • HLA class I defects in malignant lesions: What have we learned?
    • Chang CC, Campoli M, Ferrone S. HLA class I defects in malignant lesions: what have we learned? Keio J. Med. 52(4), 220-229 (2003).
    • (2003) Keio J. Med , vol.52 , Issue.4 , pp. 220-229
    • Chang, C.C.1    Campoli, M.2    Ferrone, S.3
  • 20
    • 2442654138 scopus 로고    scopus 로고
    • Promoter-dependent mechanism leading to selective hypomethylation within the 5′ region of gene MAGE-A1 in tumor cells
    • De Smet C, Loriot A, Boon T. Promoter-dependent mechanism leading to selective hypomethylation within the 5′ region of gene MAGE-A1 in tumor cells. Mol. Cell. Biol. 24(11), 4781-4790 (2004).
    • (2004) Mol. Cell. Biol , vol.24 , Issue.11 , pp. 4781-4790
    • De Smet, C.1    Loriot, A.2    Boon, T.3
  • 21
    • 0035798454 scopus 로고    scopus 로고
    • Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas
    • Arnold JM, Cummings M, Purdie D, Chenevix-Trench G. Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. Br. J. Cancer 85(9), 1351-1358 (2001).
    • (2001) Br. J. Cancer , vol.85 , Issue.9 , pp. 1351-1358
    • Arnold, J.M.1    Cummings, M.2    Purdie, D.3    Chenevix-Trench, G.4
  • 22
    • 33845310374 scopus 로고    scopus 로고
    • Epigenetic regulation of tumor endothelial cell anergy: Silencing of intercellular adhesion molecule-1 by histone modifications
    • Hellebrekers DM, Castermans K, Vire E et al. Epigenetic regulation of tumor endothelial cell anergy: silencing of intercellular adhesion molecule-1 by histone modifications. Cancer Res. 66(22), 10770-10777 (2006).
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10770-10777
    • Hellebrekers, D.M.1    Castermans, K.2    Vire, E.3
  • 23
    • 53549116447 scopus 로고    scopus 로고
    • HLA antigen changes in malignant cells: Epigenetic mechanisms and biologic significance
    • Campoli M, Ferrone S. HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance. Oncogene 27(45), 5869-5885 (2008).
    • (2008) Oncogene , vol.27 , Issue.45 , pp. 5869-5885
    • Campoli, M.1    Ferrone, S.2
  • 25
    • 0035886022 scopus 로고    scopus 로고
    • Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2′-deoxycytidine treatment
    • Serrano A, Tanzarella S, Lionello I et al. Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2′-deoxycytidine treatment. Int. J. Cancer 94(2), 243-251 (2001).
    • (2001) Int. J. Cancer , vol.94 , Issue.2 , pp. 243-251
    • Serrano, A.1    Tanzarella, S.2    Lionello, I.3
  • 26
    • 0032920527 scopus 로고    scopus 로고
    • Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR)
    • Coral S, Sigalotti L, Gasparollo A et al. Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR). J. Immunother. 22(1), 16-24 (1999).
    • (1999) J. Immunother , vol.22 , Issue.1 , pp. 16-24
    • Coral, S.1    Sigalotti, L.2    Gasparollo, A.3
  • 27
    • 0034671618 scopus 로고    scopus 로고
    • Magner WJ, Kazim AL, Stewart C et al. Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. J. Immunol. 165(12), 7017-7024 (2000).
    • Magner WJ, Kazim AL, Stewart C et al. Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. J. Immunol. 165(12), 7017-7024 (2000).
  • 28
    • 0242539831 scopus 로고    scopus 로고
    • Epigenetic targets for immune intervention in human malignancies
    • Maio M, Coral S, Fratta E, Altomonte M, Sigalotti L. Epigenetic targets for immune intervention in human malignancies. Oncogene 22(42), 6484-6488 (2003).
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6484-6488
    • Maio, M.1    Coral, S.2    Fratta, E.3    Altomonte, M.4    Sigalotti, L.5
  • 29
    • 33750584813 scopus 로고    scopus 로고
    • Epigenetic regulation of X-linked cancer/ germline antigen genes by DNMT1 and DNMT3b
    • James SR, Link PA, Karpf AR. Epigenetic regulation of X-linked cancer/ germline antigen genes by DNMT1 and DNMT3b. Oncogene 25(52), 6975-6985 (2006).
    • (2006) Oncogene , vol.25 , Issue.52 , pp. 6975-6985
    • James, S.R.1    Link, P.A.2    Karpf, A.R.3
  • 30
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • Baylin SB. DNA methylation and gene silencing in cancer. Nat. Clin. Pract. Oncol. 2(Suppl. 1), S4-S11 (2005).
    • (2005) Nat. Clin. Pract. Oncol , vol.2 , Issue.SUPPL. 1
    • Baylin, S.B.1
  • 31
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer 6(2), 107-116 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.2 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 32
    • 36549056015 scopus 로고    scopus 로고
    • Epigenetic changes in cancer
    • Gronbaek K, Hother C, Jones PA. Epigenetic changes in cancer. APMIS 115(10), 1039-1059 (2007).
    • (2007) APMIS , vol.115 , Issue.10 , pp. 1039-1059
    • Gronbaek, K.1    Hother, C.2    Jones, P.A.3
  • 33
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3(6), 415-428 (2002).
    • (2002) Nat. Rev. Genet , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 34
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 128(4), 683-692 (2007).
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 35
    • 34547914473 scopus 로고    scopus 로고
    • Unraveling the epigenetic code of cancer for therapy
    • Smith LT, Otterson GA, Plass C. Unraveling the epigenetic code of cancer for therapy. Trends Genet. 23(9), 449-456 (2007).
    • (2007) Trends Genet , vol.23 , Issue.9 , pp. 449-456
    • Smith, L.T.1    Otterson, G.A.2    Plass, C.3
  • 36
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome - components and functional correlates
    • Ting AH, McGarvey KM, Baylin SB. The cancer epigenome - components and functional correlates. Genes Dev. 20(23), 3215-3231 (2006).
    • (2006) Genes Dev , vol.20 , Issue.23 , pp. 3215-3231
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 37
    • 33745599088 scopus 로고    scopus 로고
    • Epigenetic regulation of immune escape genes in cancer
    • Tomasi TB, Magner WJ, Khan AN. Epigenetic regulation of immune escape genes in cancer. Cancer Immunol. Immunother. 55(10), 1159-1184 (2006).
    • (2006) Cancer Immunol. Immunother , vol.55 , Issue.10 , pp. 1159-1184
    • Tomasi, T.B.1    Magner, W.J.2    Khan, A.N.3
  • 38
    • 10844289762 scopus 로고    scopus 로고
    • Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine
    • Sigalotti L, Fratta E, Coral S et al. Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine. Cancer Res. 64(24), 9167-9171 (2004).
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 9167-9171
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3
  • 39
    • 25844530904 scopus 로고    scopus 로고
    • Epigenetic modulation of solid tumors as a novel approach for cancer immunotherapy
    • Sigalotti L, Coral S, Fratta E et al. Epigenetic modulation of solid tumors as a novel approach for cancer immunotherapy. Semin. Oncol. 32(5), 473-478 (2005).
    • (2005) Semin. Oncol , vol.32 , Issue.5 , pp. 473-478
    • Sigalotti, L.1    Coral, S.2    Fratta, E.3
  • 40
    • 33644879237 scopus 로고    scopus 로고
    • Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: Immunotherapeutic implications
    • Coral S, Sigalotti L, Colizzi F et al. Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications. J. Cell. Physiol. 207(1), 58-66 (2006).
    • (2006) J. Cell. Physiol , vol.207 , Issue.1 , pp. 58-66
    • Coral, S.1    Sigalotti, L.2    Colizzi, F.3
  • 41
    • 0036139334 scopus 로고    scopus 로고
    • Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma
    • Sigalotti L, Coral S, Nardi G et al. Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma. J. Immunother. 25(1), 16-26 (2002).
    • (2002) J. Immunother , vol.25 , Issue.1 , pp. 16-26
    • Sigalotti, L.1    Coral, S.2    Nardi, G.3
  • 42
    • 18344396043 scopus 로고    scopus 로고
    • Cancer testis antigens expression in mesothelioma: Role of DNA methylation and bioimmunotherapeutic implications
    • Sigalotti L, Coral S, Altomonte M et al. Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications. Br. J. Cancer 86(6), 979-982 (2002).
    • (2002) Br. J. Cancer , vol.86 , Issue.6 , pp. 979-982
    • Sigalotti, L.1    Coral, S.2    Altomonte, M.3
  • 43
    • 0036023437 scopus 로고    scopus 로고
    • 5-aza-2′-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: Immunotherapeutic implications
    • Coral S, Sigalotti L, Altomonte M et al. 5-aza-2′-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications. Clin. Cancer Res. 8(8), 2690-2695 (2002).
    • (2002) Clin. Cancer Res , vol.8 , Issue.8 , pp. 2690-2695
    • Coral, S.1    Sigalotti, L.2    Altomonte, M.3
  • 44
    • 34250621776 scopus 로고    scopus 로고
    • Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: Immunotherapeutic implications
    • Fonsatti E, Nicolay HJ, Sigalotti L et al. Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. Clin. Cancer Res. 13(11), 3333-3338 (2007).
    • (2007) Clin. Cancer Res , vol.13 , Issue.11 , pp. 3333-3338
    • Fonsatti, E.1    Nicolay, H.J.2    Sigalotti, L.3
  • 45
    • 0033539168 scopus 로고    scopus 로고
    • CpG islands as genomic footprints of promoters that are associated with replication origins
    • Antequera F, Bird A. CpG islands as genomic footprints of promoters that are associated with replication origins. Curr. Biol. 9(17), R661-R667 (1999).
    • (1999) Curr. Biol , vol.9 , Issue.17
    • Antequera, F.1    Bird, A.2
  • 46
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 447(7143), 396-398 (2007).
    • (2007) Nature , vol.447 , Issue.7143 , pp. 396-398
    • Bird, A.1
  • 47
    • 34347375106 scopus 로고    scopus 로고
    • Epigenetic drugs as pleiotropic agents in cancer treatment: Biomolecular aspects and clinical applications
    • Sigalotti L, Fratta E, Coral S et al. Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications. J. Cell. Physiol. 212(2), 330-344 (2007).
    • (2007) J. Cell. Physiol , vol.212 , Issue.2 , pp. 330-344
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3
  • 48
    • 56349090538 scopus 로고    scopus 로고
    • Epigenetics of cutaneous melanoma
    • Patino WD, Susa J. Epigenetics of cutaneous melanoma. Adv. Dermatol. 24, 59-70 (2008).
    • (2008) Adv. Dermatol , vol.24 , pp. 59-70
    • Patino, W.D.1    Susa, J.2
  • 50
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, Liang G et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res. 27(11), 2291-2298 (1999).
    • (1999) Nucleic Acids Res , vol.27 , Issue.11 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3
  • 51
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31(2), 89-97 (2006).
    • (2006) Trends Biochem. Sci , vol.31 , Issue.2 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 52
    • 0037455915 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer initiation and progression
    • Nephew KP, Huang TH. Epigenetic gene silencing in cancer initiation and progression. Cancer Lett. 190(2), 125-133 (2003).
    • (2003) Cancer Lett , vol.190 , Issue.2 , pp. 125-133
    • Nephew, K.P.1    Huang, T.H.2
  • 53
    • 33846122993 scopus 로고    scopus 로고
    • Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
    • Marks PA, Breslow R. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat. Biotechnol. 25(1), 84-90 (2007).
    • (2007) Nat. Biotechnol , vol.25 , Issue.1 , pp. 84-90
    • Marks, P.A.1    Breslow, R.2
  • 54
    • 2442454683 scopus 로고    scopus 로고
    • Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome
    • Liang G, Lin JC, Wei V et al. Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome. Proc. Natl Acad. Sci. USA 101(19), 7357-7362 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.19 , pp. 7357-7362
    • Liang, G.1    Lin, J.C.2    Wei, V.3
  • 55
    • 15744396813 scopus 로고    scopus 로고
    • The key to development: Interpreting the histone code?
    • Margueron R, Trojer P, Reinberg D. The key to development: interpreting the histone code? Curr. Opin. Genet. Dev. 15(2), 163-176 (2005).
    • (2005) Curr. Opin. Genet. Dev , vol.15 , Issue.2 , pp. 163-176
    • Margueron, R.1    Trojer, P.2    Reinberg, D.3
  • 56
    • 2642570305 scopus 로고    scopus 로고
    • The histone modification pattern of active genes revealed through genome-wide chromatin ana lysis of a higher eukaryote
    • Schubeler D, MacAlpine DM, Scalzo D et al. The histone modification pattern of active genes revealed through genome-wide chromatin ana lysis of a higher eukaryote. Genes Dev. 18(11), 1263-1271 (2004).
    • (2004) Genes Dev , vol.18 , Issue.11 , pp. 1263-1271
    • Schubeler, D.1    MacAlpine, D.M.2    Scalzo, D.3
  • 57
    • 4744344066 scopus 로고    scopus 로고
    • Epigenetics and cancer
    • Lund AH, van Lohuizen M. Epigenetics and cancer. Genes Dev. 18(19), 2315-2335 (2004).
    • (2004) Genes Dev , vol.18 , Issue.19 , pp. 2315-2335
    • Lund, A.H.1    van Lohuizen, M.2
  • 58
    • 0021999503 scopus 로고
    • Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens
    • Feizi T. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature 314(6006), 53-57 (1985).
    • (1985) Nature , vol.314 , Issue.6006 , pp. 53-57
    • Feizi, T.1
  • 59
    • 0025210042 scopus 로고
    • Circulating tumor markers in breast cancer (review)
    • Jotti GS, Bombardieri E. Circulating tumor markers in breast cancer (review). Anticancer Res. 10(1), 253-258 (1990).
    • (1990) Anticancer Res , vol.10 , Issue.1 , pp. 253-258
    • Jotti, G.S.1    Bombardieri, E.2
  • 60
    • 1542327606 scopus 로고    scopus 로고
    • Identification of tumour antigens by serological ana lysis of cDNA expression cloning
    • Li G, Miles A, Line A, Rees RC. Identification of tumour antigens by serological ana lysis of cDNA expression cloning. Cancer Immunol. Immunother. 53(3), 139-143 (2004).
    • (2004) Cancer Immunol. Immunother , vol.53 , Issue.3 , pp. 139-143
    • Li, G.1    Miles, A.2    Line, A.3    Rees, R.C.4
  • 61
    • 11144232998 scopus 로고    scopus 로고
    • Human high molecular weight-melanoma-associated antigen (HMW-MAA): A melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance
    • Campoli MR, Chang CC, Kageshita T, Wang X, McCarthy JB, Ferrone S. Human high molecular weight-melanoma-associated antigen (HMW-MAA): a melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance. Crit. Rev. Immunol. 24(4), 267-296 (2004).
    • (2004) Crit. Rev. Immunol , vol.24 , Issue.4 , pp. 267-296
    • Campoli, M.R.1    Chang, C.C.2    Kageshita, T.3    Wang, X.4    McCarthy, J.B.5    Ferrone, S.6
  • 62
    • 0029029450 scopus 로고
    • Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: Modulation of the immunogenicity in patients with malignant melanoma
    • Mittelman A, Chen GZ, Wong GY, Liu C, Hirai S, Ferrone S. Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: modulation of the immunogenicity in patients with malignant melanoma. Clin. Cancer Res. 1(7), 705-713 (1995).
    • (1995) Clin. Cancer Res , vol.1 , Issue.7 , pp. 705-713
    • Mittelman, A.1    Chen, G.Z.2    Wong, G.Y.3    Liu, C.4    Hirai, S.5    Ferrone, S.6
  • 63
    • 33646709661 scopus 로고    scopus 로고
    • Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells
    • Luo W, Wang X, Kageshita T, Wakasugi S, Karpf AR, Ferrone S. Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells. Oncogene 25(20), 2873-2884 (2006).
    • (2006) Oncogene , vol.25 , Issue.20 , pp. 2873-2884
    • Luo, W.1    Wang, X.2    Kageshita, T.3    Wakasugi, S.4    Karpf, A.R.5    Ferrone, S.6
  • 65
    • 0033595632 scopus 로고    scopus 로고
    • Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: Correlation with clinical events
    • Jager E, Stockert E, Zidianakis Z et al. Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: correlation with clinical events. Int. J. Cancer 84(5), 506-510 (1999).
    • (1999) Int. J. Cancer , vol.84 , Issue.5 , pp. 506-510
    • Jager, E.1    Stockert, E.2    Zidianakis, Z.3
  • 66
    • 2642673605 scopus 로고    scopus 로고
    • A survey of the humoral immune response of cancer patients to a panel of human tumor antigens
    • Stockert E, Jager E, Chen YT et al. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J. Exp. Med. 187(8), 1349-1354 (1998).
    • (1998) J. Exp. Med , vol.187 , Issue.8 , pp. 1349-1354
    • Stockert, E.1    Jager, E.2    Chen, Y.T.3
  • 67
    • 2642683198 scopus 로고    scopus 로고
    • Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes
    • Jager E, Chen YT, Drijfhout JW et al. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes. J. Exp. Med. 187(2), 265-270 (1998).
    • (1998) J. Exp. Med , vol.187 , Issue.2 , pp. 265-270
    • Jager, E.1    Chen, Y.T.2    Drijfhout, J.W.3
  • 68
    • 0036813331 scopus 로고    scopus 로고
    • Cancer/testis antigens: An expanding family of targets for cancer immunotherapy
    • Scanlan MJ, Gure AO, Jungbluth AA, Old LJ, Chen YT. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol. Rev. 188, 22-32 (2002).
    • (2002) Immunol. Rev , vol.188 , pp. 22-32
    • Scanlan, M.J.1    Gure, A.O.2    Jungbluth, A.A.3    Old, L.J.4    Chen, Y.T.5
  • 69
    • 0037364292 scopus 로고    scopus 로고
    • Cancer/testis-associated genes: Identification, expression profile, and putative function
    • Zendman AJ, Ruiter DJ, van Muijen GN. Cancer/testis-associated genes: identification, expression profile, and putative function. J. Cell. Physiol. 194(3), 272-288 (2003).
    • (2003) J. Cell. Physiol , vol.194 , Issue.3 , pp. 272-288
    • Zendman, A.J.1    Ruiter, D.J.2    van Muijen, G.N.3
  • 70
    • 11144290778 scopus 로고    scopus 로고
    • Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: Immunotherapeutic implications
    • Calabro L, Fonsatti E, Altomonte M et al. Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: immunotherapeutic implications. J. Cell. Physiol. 202(2), 474-477 (2005).
    • (2005) J. Cell. Physiol , vol.202 , Issue.2 , pp. 474-477
    • Calabro, L.1    Fonsatti, E.2    Altomonte, M.3
  • 71
    • 25844432413 scopus 로고    scopus 로고
    • Epigenetic immunomodulation of hematopoietic malignancies
    • Gattei V, Fonsatti E, Sigalotti L et al. Epigenetic immunomodulation of hematopoietic malignancies. Semin. Oncol. 32(5), 503-510 (2005).
    • (2005) Semin. Oncol , vol.32 , Issue.5 , pp. 503-510
    • Gattei, V.1    Fonsatti, E.2    Sigalotti, L.3
  • 72
    • 17044445366 scopus 로고    scopus 로고
    • Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines
    • dos Santos NR, Torensma R, de Vries TJ et al. Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines. Cancer Res. 60(6), 1654-1662 (2000).
    • (2000) Cancer Res , vol.60 , Issue.6 , pp. 1654-1662
    • dos Santos, N.R.1    Torensma, R.2    de Vries, T.J.3
  • 73
    • 0033931860 scopus 로고    scopus 로고
    • Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours
    • Jungbluth AA, Stockert E, Chen YT et al. Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours. Br. J. Cancer 83(4), 493-497 (2000).
    • (2000) Br. J. Cancer , vol.83 , Issue.4 , pp. 493-497
    • Jungbluth, A.A.1    Stockert, E.2    Chen, Y.T.3
  • 74
    • 0035876940 scopus 로고    scopus 로고
    • Immunohistochemical ana lysis of NY-ESO-1 antigen expression in normal and malignant human tissues
    • Jungbluth AA, Chen YT, Stockert E et al. Immunohistochemical ana lysis of NY-ESO-1 antigen expression in normal and malignant human tissues. Int. J. Cancer 92(6), 856-860 (2001).
    • (2001) Int. J. Cancer , vol.92 , Issue.6 , pp. 856-860
    • Jungbluth, A.A.1    Chen, Y.T.2    Stockert, E.3
  • 75
    • 0029957792 scopus 로고    scopus 로고
    • The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation
    • De Smet C, De Backer O, Faraoni I, Lurquin C, Brasseur F, Boon T. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. Proc. Natl Acad. Sci. USA 93(14), 7149-7153 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.14 , pp. 7149-7153
    • De Smet, C.1    De Backer, O.2    Faraoni, I.3    Lurquin, C.4    Brasseur, F.5    Boon, T.6
  • 76
    • 1642394277 scopus 로고    scopus 로고
    • Demethylation of MAGE promoters during gastric cancer progression
    • Honda T, Tamura G, Waki T et al. Demethylation of MAGE promoters during gastric cancer progression. Br. J. Cancer 90(4), 838-843 (2004).
    • (2004) Br. J. Cancer , vol.90 , Issue.4 , pp. 838-843
    • Honda, T.1    Tamura, G.2    Waki, T.3
  • 77
    • 0029118803 scopus 로고
    • Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene
    • De Smet C, Courtois SJ, Faraoni I et al. Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene. Immunogenetics 42(4), 282-290 (1995).
    • (1995) Immunogenetics , vol.42 , Issue.4 , pp. 282-290
    • De Smet, C.1    Courtois, S.J.2    Faraoni, I.3
  • 78
    • 40949121440 scopus 로고    scopus 로고
    • Cancer testis antigens in human melanoma stem cells: Expression, distribution, and methylation status
    • Sigalotti L, Covre A, Zabierowski S et al. Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status. J. Cell. Physiol. 215(2), 287-291 (2008).
    • (2008) J. Cell. Physiol , vol.215 , Issue.2 , pp. 287-291
    • Sigalotti, L.1    Covre, A.2    Zabierowski, S.3
  • 79
    • 33947546035 scopus 로고    scopus 로고
    • Epigenetic regulation of human cancer/testis antigen gene, HAGE, in chronic myeloid leukemia
    • Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. Epigenetic regulation of human cancer/testis antigen gene, HAGE, in chronic myeloid leukemia. Haematologica 92(2), 153-162 (2007).
    • (2007) Haematologica , vol.92 , Issue.2 , pp. 153-162
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3
  • 80
    • 34848908897 scopus 로고    scopus 로고
    • Epigenetic regulation of PRAME gene in chronic myeloid leukemia
    • Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. Epigenetic regulation of PRAME gene in chronic myeloid leukemia. Leuk. Res. 31(11), 1521-1528 (2007).
    • (2007) Leuk. Res , vol.31 , Issue.11 , pp. 1521-1528
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3
  • 81
    • 34047244043 scopus 로고    scopus 로고
    • 5-aza-2′ deoxycytidine in cancer immunotherapy: A mouse to man story
    • Coral S, Sigalotti L, Covre A, Nicolay HJ, Natali PG, Maio M. 5-aza-2′ deoxycytidine in cancer immunotherapy: a mouse to man story. Cancer Res. 67(6), 2900-2901 (2007).
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2900-2901
    • Coral, S.1    Sigalotti, L.2    Covre, A.3    Nicolay, H.J.4    Natali, P.G.5    Maio, M.6
  • 82
    • 24744456138 scopus 로고    scopus 로고
    • Targeting the epigenome for the treatment and prevention of lung cancer
    • Schrump DS, Nguyen DM. Targeting the epigenome for the treatment and prevention of lung cancer. Semin. Oncol. 32(5), 488-502 (2005).
    • (2005) Semin. Oncol , vol.32 , Issue.5 , pp. 488-502
    • Schrump, D.S.1    Nguyen, D.M.2
  • 83
    • 0035126974 scopus 로고    scopus 로고
    • Sequential 5-aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1
    • Weiser TS, Guo ZS, Ohnmacht GA et al. Sequential 5-aza-2 deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1. J. Immunother. 24(2), 151-161 (2001).
    • (2001) J. Immunother , vol.24 , Issue.2 , pp. 151-161
    • Weiser, T.S.1    Guo, Z.S.2    Ohnmacht, G.A.3
  • 84
    • 0035132573 scopus 로고    scopus 로고
    • Induction of MAGE-3 expression in lung and esophageal cancer cells
    • Weiser TS, Ohnmacht GA, Guo ZS et al. Induction of MAGE-3 expression in lung and esophageal cancer cells. Ann. Thorac. Surg. 71(1), 295-301 (2001).
    • (2001) Ann. Thorac. Surg , vol.71 , Issue.1 , pp. 295-301
    • Weiser, T.S.1    Ohnmacht, G.A.2    Guo, Z.S.3
  • 85
    • 33744829728 scopus 로고    scopus 로고
    • Promoter demethylation and histone ace tyl ation mediate gene expression of MAGE- A1, -A2, -A3, and -A12 in human cancer cells
    • Wischnewski F, Pantel K, Schwarzenbach H. Promoter demethylation and histone ace tyl ation mediate gene expression of MAGE- A1, -A2, -A3, and -A12 in human cancer cells. Mol. Cancer Res. 4(5), 339-349 (2006).
    • (2006) Mol. Cancer Res , vol.4 , Issue.5 , pp. 339-349
    • Wischnewski, F.1    Pantel, K.2    Schwarzenbach, H.3
  • 86
    • 0028328854 scopus 로고
    • Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine
    • Weber J, Salgaller M, Samid D et al. Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2′-deoxycytidine. Cancer Res. 54(7), 1766-1771 (1994).
    • (1994) Cancer Res , vol.54 , Issue.7 , pp. 1766-1771
    • Weber, J.1    Salgaller, M.2    Samid, D.3
  • 87
    • 54249111906 scopus 로고    scopus 로고
    • Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition
    • Pellicciotta I, Cortez-Gonzalez X, Sasik R et al. Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition. Cancer Res. 68(19), 8085-8093 (2008).
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8085-8093
    • Pellicciotta, I.1    Cortez-Gonzalez, X.2    Sasik, R.3
  • 88
    • 0242624621 scopus 로고    scopus 로고
    • Targeted therapy of solid malignancies via HLA class II antigens: A new biotherapeutic approach?
    • Altomonte M, Fonsatti E, Visintin A, Maio M. Targeted therapy of solid malignancies via HLA class II antigens: a new biotherapeutic approach? Oncogene 22(42), 6564-6569 (2003).
    • (2003) Oncogene , vol.22 , Issue.42 , pp. 6564-6569
    • Altomonte, M.1    Fonsatti, E.2    Visintin, A.3    Maio, M.4
  • 89
    • 27744503577 scopus 로고    scopus 로고
    • Chou SD, Khan AN, Magner WJ, Tomasi TB. Histone acetylation regulates the cell type specific CIITA promoters, MHC class II expression and antigen presentation in tumor cells. Int. Immunol. 17(11), 1483-1494 (2005).
    • Chou SD, Khan AN, Magner WJ, Tomasi TB. Histone acetylation regulates the cell type specific CIITA promoters, MHC class II expression and antigen presentation in tumor cells. Int. Immunol. 17(11), 1483-1494 (2005).
  • 90
    • 31544432509 scopus 로고    scopus 로고
    • De novo induction of a cancer/ testis antigen by 5-aza-2′-deoxycytidine augments adoptive immunotherapy in a murine tumor model
    • Guo ZS, Hong JA, Irvine KR et al. De novo induction of a cancer/ testis antigen by 5-aza-2′-deoxycytidine augments adoptive immunotherapy in a murine tumor model. Cancer Res. 66(2), 1105-1113 (2006).
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1105-1113
    • Guo, Z.S.1    Hong, J.A.2    Irvine, K.R.3
  • 91
    • 39049115955 scopus 로고    scopus 로고
    • Khan AN, Magner W, Tomasi T. An epigenetic vaccine model active in the prevention and treatment of melanoma. J. Trans. Med. 5(1), 64 (2007).
    • Khan AN, Magner W, Tomasi T. An epigenetic vaccine model active in the prevention and treatment of melanoma. J. Trans. Med. 5(1), 64 (2007).
  • 92
    • 34547989446 scopus 로고    scopus 로고
    • Decitabine and its role in the treatment of hematopoietic malignancies
    • Plimack ER, Kantarjian HM, Issa JP. Decitabine and its role in the treatment of hematopoietic malignancies. Leuk. Lymphoma 48(8), 1472-1481 (2007).
    • (2007) Leuk. Lymphoma , vol.48 , Issue.8 , pp. 1472-1481
    • Plimack, E.R.1    Kantarjian, H.M.2    Issa, J.P.3
  • 93
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa JP, Garcia-Manero G, Giles FJ et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 103(5), 1635-1640 (2004).
    • (2004) Blood , vol.103 , Issue.5 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 94
    • 33846011361 scopus 로고    scopus 로고
    • Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • Kantarjian H, Oki Y, Garcia-Manero G et al. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 109(1), 52-57 (2007).
    • (2007) Blood , vol.109 , Issue.1 , pp. 52-57
    • Kantarjian, H.1    Oki, Y.2    Garcia-Manero, G.3
  • 95
    • 41349083325 scopus 로고    scopus 로고
    • Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia
    • Oki Y, Jelinek J, Shen L, Kantarjian HM, Issa JP. Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia. Blood 111(4), 2382-2384 (2008).
    • (2008) Blood , vol.111 , Issue.4 , pp. 2382-2384
    • Oki, Y.1    Jelinek, J.2    Shen, L.3    Kantarjian, H.M.4    Issa, J.P.5
  • 96
    • 0037962005 scopus 로고    scopus 로고
    • Results of decitabine (5-aza-2′deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia
    • Kantarjian HM, O'brien S, Cortes J et al. Results of decitabine (5-aza-2′deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia. Cancer 98(3), 522-528 (2003).
    • (2003) Cancer , vol.98 , Issue.3 , pp. 522-528
    • Kantarjian, H.M.1    O'brien, S.2    Cortes, J.3
  • 97
    • 17444452612 scopus 로고    scopus 로고
    • Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: A multicenter Phase II study in elderly patients
    • Wijermans P, Lubbert M, Verhoef G et al. Low-dose 5-aza-2′-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter Phase II study in elderly patients. J. Clin. Oncol. 18(5), 956-962 (2000).
    • (2000) J. Clin. Oncol , vol.18 , Issue.5 , pp. 956-962
    • Wijermans, P.1    Lubbert, M.2    Verhoef, G.3
  • 98
    • 0019997881 scopus 로고
    • Combinational chemotherapy of L1210 and L1210/ARA-C leukemia with 5-aza-2′-deoxycytidine and b-2′-deoxythioguanosine
    • Momparler RL, Momparler LF, Samson J. Combinational chemotherapy of L1210 and L1210/ARA-C leukemia with 5-aza-2′-deoxycytidine and b-2′-deoxythioguanosine. Int. J. Cancer 30(3), 361-364 (1982).
    • (1982) Int. J. Cancer , vol.30 , Issue.3 , pp. 361-364
    • Momparler, R.L.1    Momparler, L.F.2    Samson, J.3
  • 99
    • 33744918070 scopus 로고    scopus 로고
    • DNA methylation changes after 5-aza-2′-deoxy-cytidine therapy in patients with leukemia
    • Yang AS, Doshi KD, Choi SW et al. DNA methylation changes after 5-aza-2′-deoxy-cytidine therapy in patients with leukemia. Cancer Res. 66(10), 5495-5503 (2006).
    • (2006) Cancer Res , vol.66 , Issue.10 , pp. 5495-5503
    • Yang, A.S.1    Doshi, K.D.2    Choi, S.W.3
  • 100
    • 0038142344 scopus 로고    scopus 로고
    • 5-aza-2′-deoxycytidine (decitabine) treatment of hematopoietic malignancies: A multimechanism therapeutic approach?
    • Sigalotti L, Altomonte M, Colizzi F et al. 5-aza-2′-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach? Blood 101(11), 4644-4646 (2003).
    • (2003) Blood , vol.101 , Issue.11 , pp. 4644-4646
    • Sigalotti, L.1    Altomonte, M.2    Colizzi, F.3
  • 101
    • 0344990164 scopus 로고    scopus 로고
    • Phase I trial of continuous infusion 5-aza-2′-deoxycytidine
    • Aparicio A, Eads CA, Leong LA et al. Phase I trial of continuous infusion 5-aza-2′-deoxycytidine. Cancer Chemother. Pharmacol. 51(3), 231-239 (2003).
    • (2003) Cancer Chemother. Pharmacol , vol.51 , Issue.3 , pp. 231-239
    • Aparicio, A.1    Eads, C.A.2    Leong, L.A.3
  • 102
    • 21244449980 scopus 로고    scopus 로고
    • Evaluation of a 7-day continuous intravenous infusion of decitabine: Inhibition of promoter-specific and global genomic DNA methylation
    • Samlowski WE, Leachman SA, Wade M et al. Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation. J. Clin. Oncol. 23(17), 3897-3905 (2005).
    • (2005) J. Clin. Oncol , vol.23 , Issue.17 , pp. 3897-3905
    • Samlowski, W.E.1    Leachman, S.A.2    Wade, M.3
  • 103
    • 33750326078 scopus 로고    scopus 로고
    • Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura
    • Schrump DS, Fischette MR, Nguyen DM et al. Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clin. Cancer Res. 12(19), 5777-5785 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.19 , pp. 5777-5785
    • Schrump, D.S.1    Fischette, M.R.2    Nguyen, D.M.3
  • 104
    • 33748046812 scopus 로고    scopus 로고
    • Phase I trial of sequential low-dose 5-aza-2′-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma
    • Gollob JA, Sciambi CJ, Peterson BL et al. Phase I trial of sequential low-dose 5-aza-2′-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma. Clin. Cancer Res. 12(15), 4619-4627 (2006).
    • (2006) Clin. Cancer Res , vol.12 , Issue.15 , pp. 4619-4627
    • Gollob, J.A.1    Sciambi, C.J.2    Peterson, B.L.3
  • 105
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • Minucci S, Pelicci PG. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat. Rev. Cancer 6(1), 38-51 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 106
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • Bolden JE, Peart MJ, Johnstone RW. Anticancer activities of histone deacetylase inhibitors. Nat. Rev. Drug Discov. 5(9), 769-784 (2006).
    • (2006) Nat. Rev. Drug Discov , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.