Induction of MAGE-3 expression in lung and esophageal cancer cells

Annals of Thoracic Surgery

Volumn 71, Issue 1, 2001, Pages 295-302

  Weiser, Todd S ^a   Ohnmacht, Galen A ^a   Guo, Zong S ^a   Fischette, Maria R ^a   Chen, Gustavio A ^a   Hong, Julie A ^a   Nguyen, Dao M ^a   Schrump, David S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DEPSIPEPTIDE; FR 901228; HISTONE DEACETYLASE INHIBITOR; HLA ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; ESOPHAGUS CANCER; FLOW CYTOMETRY; GENE INDUCTION; GROWTH DISORDER; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG CANCER; PRIORITY JOURNAL; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIGENS, NEOPLASM; AZACITIDINE; CARCINOMA, NON-SMALL-CELL LUNG; DEPSIPEPTIDES; DNA MODIFICATION METHYLASES; ENZYME INHIBITORS; ESOPHAGEAL NEOPLASMS; HISTONE DEACETYLASES; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MELANOMA; NEOPLASM PROTEINS; PEPTIDES, CYCLIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0035132573     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(00)02421-8     Document Type: Article

References (37)

1. Targets for molecular intervention m multistep pulmonary carcinogenesis
2. Strategies for molecular intervention in esophageal cancers and their precursor lesions
3. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes
4. T cell defined tumor antigens
5. Distribution of human leukocyte antigen-ABC and -D/DR antigens in the unfixed human testis
6. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
7. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
8. Expression of MAGE genes by non-small-cell lung carcinomas
9. IFN-gamma gene transfer restores HLA-class I expression and MAGE-3 antigen presentation to CTL in HLA-deficient small cell lung cancer
10. Human esophageal carcinomas frequently express the tumor-rejection antigens of MAGE genes
11. Molecular basis for lack of expression of HLA class I antigens in human small-cell lung carcinoma cell lines
12. Alterations in DNA methylation: A fundamental aspect of neoplasia
13. CpG methylation, chromatin structure and gene silencing - A three-way connection
14. Methylation, gene expression and the chromatin connection in cance
15. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation
16. NY-ESO-1 may be a potential target for lung cancer immunotherapy
17. The DNA methylation paradox
18. INK4 protein induction by 5-aza 2′ deoxycytidine
19. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
20. Real time quantitative PCR
21. Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood
22. Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T-lymphocytes
23. Functional analysis of antigen-specific T lymphocytes by serial measurement of gene expression in peripheral blood mononuclear cells and tumor specimens
24. Structure, chromosomal localization, and expression of 12 genes of the MAGE family
25. Expression of MAGE-antigens in normal tissues and cancer
26. Induction of antitumor cytotoxic T lymphocytes from the peripheral blood mononuclear cells of cancer patients using HLA-A2-restricted MAGE-3 peptide in vitro
27. Estimation of the frequencies of anti-MAGE-3 cytolytic T-lymphocyte precursors in blood from individuals without cancer
28. Frequency of MAGE-3 gene expression in HLA-A2 positive patients with non-small cell lung cancer
29. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens
30. Variable expression on lung cancer cell lines of HLA-A2-binding MAGE-3 peptide recognized by cytotoxic T lymphocytes
31. Molecular, cellular and animal pharmacology of 5-Aza-2′-deoxycytidine
32. k) products on immunogenic variants of a spontaneous murine carcinoma
33. FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity
34. FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968. III. Antitumor activities on experimental tumors in mice
35. Cytidine analogues
36. MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T cymphocyte
37. Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell response