The three trehalases Nth1p, Nth2p and Ath1p participate in the mobilization of intracellular trehalose required for recovery from saline stress in Saccharomyces cerevisiae

Microbiology

Volumn 155, Issue 9, 2009, Pages 3092-3099

  Garre, Elena ^a   Matallana, Emilia ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AGT1P PROTON COTRANSPORTER; COTRANSPORTER; PROTEIN ATH1P; PROTEIN NTH1P; PROTEIN NTH2P; TREHALASE; TREHALOSE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE METABOLISM; CARBOHYDRATE TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL METABOLISM; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS MUTANT; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SALT STRESS; SIGNAL TRANSDUCTION;

GENE DELETION; GENES, FUNGAL; MONOSACCHARIDE TRANSPORT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL; SYMPORTERS; TREHALASE; TREHALOSE;

SACCHAROMYCES CEREVISIAE;

EID: 69949127785     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.024992-0     Document Type: Article

References (41)

1. Alizadeh, P. & Klionsky, D. J. (1996). Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae. FEBS Lett 391, 273-278.
2. Basu, A., Bhattacharyya, S., Chaudhuri, P., Sengupta, S. & Ghosh, A. K. (2006). Extracellular trehalose utilization by Saccharomyces cerevisiae. Biochim Biophys Acta 1760, 134-140.
3. Blomberg, A. (2000). Metabolic surprises in Saccharomyces cerevisiae during adaptation to saline conditions: questions, some answers and a model. FEMS Microbiol Lett 182, 1-8.
4. Crowe, J. H., Hoekstra, F. A. & Crowe, L. M. (1992). Anhydrobiosis. Annu Rev Physiol 54, 579-599.
5. De Mesquita, J. F., Paschoalin, V. M. & Panek, A. D. (1997). Modulation of trehalase activity in Saccharomyces cerevisiae by an intrinsic protein. Biochim Biophys Acta 1334, 233-239.
6. De Mesquita, J. F., Panek, A. D. & de Araujo, P. S. (2003). In silico and in vivo analysis reveal a novel gene in Saccharomyces cerevisiae trehalose metabolism. BMC Genomics 4, 45.
7. Destruelle, M., Holzer, H. & Klionsky, D. J. (1995). Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity. Yeast 11, 1015-1025.
8. Garre, E., Peérez-Torrado, R., Gimeno-Alcañiz, J. V. & Matallana, E. (2009). Acid trehalase is involved in intracellular trehalose mobilization during postdiauxic growth and severe saline stress in Saccharomyces cerevisiae. FEMS Yeast Res 9, 52-62.
9. Gietz, R. D., Schiestl, R. H., Willems, A. R. & Woods, R. A. (1995). Studies on the transformation of intact yeast cells by the LiAc/SSDNA/PEG procedure. Yeast 11, 355-360.
10. González-Hernández, J. C., Jiménez-Estrada, M. & Pena, A. (2005). Comparative analysis of trehalose production by Debaryomyces hansenii and Saccharomyces cerevisiae under saline stress. Extremophiles 9, 7-16.
11. Güldener, U., Heck, S., Fielder, T., Beinhauer, J. & Hegemann, J. H. (1996). A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res 24, 2519-2524.
12. Harris, S. D. & Cotter, D. A. (1988). Transport of yeast vacuolar trehalase to the vacuole. Can J Microbiol 34, 835-838.
13. Hottiger, T., Schmutz, P. & Wiemken, A. (1987). Heat-induced accumulation and futile cycling of trehalose in Saccharomyces cerevisiae. J Bacteriol 169, 5518-5522.
14. Huang, J., Reggiori, F. & Klionsky, D. J. (2007). The transmembrane domain of acid trehalase mediates ubiquitin-independent multivesicular body pathway sorting. Mol Biol Cell 18, 2511-2524.
15. Jules, M., Guillou, V., François, J. & Parrou, J. L. (2004). Two distinct pathways for trehalose assimilation in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 70, 2771-2778.
16. Jules, M., Beltrán, G., Françcois, J. & Parrou, J. L. (2008). New insights in yeast trehalose metabolism: NTH2 encodes a functional cytosolic trehalase, and deletion of TPS1 reveals a Ath1p-dependent trehalose mobilization. Appl Environ Microbiol 74, 605-614.
17. Jung, Y. J. & Park, H. D. (2005). Antisense-mediated inhibition of acid trehalase (ATH1) gene expression promotes ethanol fermentation and tolerance in Saccharomyces cerevisiae. Biotechnol Lett 27, 1855-1859.
18. Keller, F., Schellenberg, M. & Wiemken, A. (1982). Localization of trehalase in vacuoles and of trehalose in the cytosol of yeast (Saccharomyces cerevisiae). Arch Microbiol 131, 298-301.
19. Kim, J., Alizadeh, P., Harding, T., Hefner-Gravink, A. & Klionsky, D. J. (1996). Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications. Appl Environ Microbiol 62, 1563-1569.
20. Mahmud, S. A., Nagahisa, K., Hirasawa, T., Yoshikawa, K., Ashitani, K. & Shimizu, H. (2009). Effect of trehalose accumulation on response to saline stress in Sacccharomyces cerevisiae. Yeast 26, 17-30.
21. Malluta, E. F., Decker, P. & Stambuk, B. U. (2000). The Kluyver effect for trehalose in Saccharomyces cerevisiae. J Basic Microbiol 40, 199-205.
22. Nwaka, S. & Holzer, H. (1998). Molecular biology of trehalose and the trehalases in the yeast Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol 58, 197-237.
23. Nwaka, S., Mechler, B., Destruelle, M. & Holzer, H. (1995a). Phenotypic features of trehalase mutants in Saccharomyces cerevisiae. FEBS Lett 360, 286-290.
24. Nwaka, S., Kopp, M. & Holzer, H. (1995b). Expression and function of the trehalase genes NTH1 and YBR0106 in Saccharomyces cerevisiae. J Biol Chem 270, 10193-10198.
25. Nwaka, S., Mechler, B. & Holzer, H. (1996). Deletion of the ATH1 gene in Saccharomyces cerevisiae prevents growth on trehalose. FEBS Lett 386, 235-238.
26. Panadero, J., Pallotti, C., Rodríguez-Vargas, S., Randez-Gil, F. & Prieto, J. A. (2006). A downshift in temperature activates the high osmolarity glycerol (HOG) pathway, which determines freeze tolerance in Saccharomyces cerevisiae. J Biol Chem 281, 4638-4645.
27. Parrou, J. L. & François, J. (1997). A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells. Anal Biochem 248, 186-188.
28. Parrou, J. L., Teste, M. A. & François, J. (1997). Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose. Microbiology 143, 1891-1900.
29. 2 in Saccharomyces cerevisiae mutants deficient in trehalase genes. Arch Microbiol 177, 494-499.
30. Plourde-Owobi, L., Durner, S., Parrou, J. L., Wieczorke, R., Goma, G. & François, J. (1999). AGT1, encoding an alpha-glucoside transporter involved in uptake and intracellular accumulation of trehalose in Saccharomyces cerevisiae. J Bacteriol 181, 3830-3832.
31. San Miguel, P. F. & Argüelles, J. C. (1994). Differential changes in the activity of cytosolic and vacuolar trehalases along the growth cycle of Saccharomyces cerevisiae. Biochim Biophys Acta 1200, 155-160.
32. Sebollela, A., Louzada, P. R., Sola-Penna, M., Sarone-Williams, V., Coelho-Sampaio, T. & Ferreira, S. T. (2004). Inhibition of yeast glutathione reductase by trehalose: possible implications in yeast survival and recovery from stress. Int J Biochem Cell Biol 36, 900-908.
33. Singer, M. A. & Lindquist, S. (1998a). Multiple effects of trehalose on protein folding in vitro and in vivo. Mol Cell 1, 639-648.
34. Singer, M. A. & Lindquist, S. (1998b). Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose. Trends Biotechnol 16, 460-468.
35. Van Dijck, P., Colavizza, D., Smet, P. & Thevelein, J. M. (1995). Differential importance of trehalose in stress resistance in fermenting and nonfermenting Saccharomyces cerevisiae cells. Appl Environ Microbiol 61, 109-115.
36. Wera, S., De Schrijver, E., Geyskens, I., Nwaka, S. & Thevelein, J. M. (1999). Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae. Biochem J 343, 621-626.
37. Winderickx, J., de Winde, J. H., Crauwels, M., Hino, A., Hohmann, S., Van Dijck, P. & Thevelein, J. M. (1996). Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252, 470-482.
38. Wolfe, K. H. & Lohan, A. J. (1994). Sequence around the centromere of Saccharomyces cerevisiae chromosome II: similarity of CEN2 to CEN4. Yeast 10 (Suppl A), S41-S46.
39. Zahringer, H., Burgert, M., Holzer, H. & Nwaka, S. (1997). Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein. FEBS Lett 412 , 615-620.
40. Zahringer, H., Holzer, H. & Nwaka, S. (1998). Stability of neutral trehalase during heat stress in Saccharomyces cerevisiae is dependent on the activity of the catalytic subunits of cAMP-dependent protein kinase, Tpk1 and Tpk2. Eur J Biochem 255, 544-551.
41. Zahringer, H., Thevelein, J. M. & Nwaka, S. (2000). Induction of neutral trehalase Nth1 by heat and osmotic stress is controlled by STRE elements and Msn2/Msn4 transcription factors: variations of PKA effect during stress and growth. Mol Microbiol 35, 397-406.