Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: Genetic evidence for a stress-induced recycling of glycogen and trehalose

Microbiology

Volumn 143, Issue 6, 1997, Pages 1891-1900

  Parrou, Jean Luc ^a   Teste, Marie Ange ^a   François, Jean ^a  

^a CEMAGREF   (France)

Author keywords

Glycogen; Saccharomyces cerevisiae; Stress response; Transcriptional regulation; Trehalose

Indexed keywords

CARBOHYDRATE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; SYNTHETASE; TREHALASE; TREHALOSE;

ARTICLE; BIODEGRADATION; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; FUNGAL GENETICS; FUNGUS MUTANT; GENE INDUCTION; GLYCOGEN METABOLISM; HEAT STRESS; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; RECYCLING; SACCHAROMYCES CEREVISIAE; STRESS; TRANSCRIPTION REGULATION;

FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0030878249     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-143-6-1891     Document Type: Article

References (48)

1. Alizadeh, P. & Klionsky, D. J. (1996). Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae. FEBS Lett 391, 273-278.
2. Attfield, P. V., Kletsas, S. & Hazell, B. W. (1994). Concomitant appearance of intrinsic thermotolerance and storage of trehalose in Saccharomyces cerevisiae during early respiratory phase of batch-culture is CIF1-dependent. Microbiology 140, 2625-2632.
3. Becker, J. U. (1978). A method for glycogen determination in whole yeast cells. Anal Biochem 86, 56-64.
4. Bell, W., Klaassen, P., Ohnacker, M., Boller, T., Herweijer, M., Schoppink, P., Van Der Zee, P. & Wiemken, A. (1992). Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209, 951-959.
5. Boorstein, W. R. & Craig, E. A. (1990). Regulation of a yeast HSP70 gene by a cAMP responsive transcriptional control element. EMBO J 9, 2543-2553.
6. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72, 248-254.
7. Cheng, C., Mu, J., Farkas, I., Huang, D., Goebl, M. G. & Roach, P. J. (1995). Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae. Mol Cell Biochem 15, 6632-6640.
8. Destruelle, M., Holzer, H. & Klionsky, D. J. (1995). Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity. Yeast 11, 1015-1025.
9. De Virgilio, C., Piper, P., Boller, T. & Wiemken, A. (1991). Acquisition of thermotolerance in Saccharomyces cerevisiae without heat shock protein hsp104 and in the absence of protein synthesis. FEBS Lett 288, 86-90.
10. De Virgilio, C., Bürckert, N., Bell, W., Jenö, P., Boller, T. & Wiemken, A. (1993). Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity. Eur J Biochem 212, 315-323.
11. De Virgilio, C., Hottiger, T., Dominguez, T., Boller, T. & Wiemken, A. (1994). The role of trehalose synthesis for the acquisition of thermotolerance in yeast. I. Genetic evidence that trehalose is a thermoprotectant. Eur J Biochem 219, 179-186.
12. Farkas, I., Hardy, T. A., Goebl, M. G. & Roach, P. J. (1991). Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled. J Biol Chem 266, 15602-15607.
13. François, J., Villanueva, M. E. & Hers, H. G. (1988). The control of glycogen metabolism in yeast. I. Interconversion in vivo of glycogen synthase and glycogen phosphorylase induced by glucose, a nitrogen source or uncouplers. Eur J Biochem 174, 551-559.
14. François, J., Thompson-Jaeger, J. S., Zellenka, U., Spevak, W. & Tatchell, K. (1992). Gac1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae. EMBO J 11, 87-96.
15. François, J., Blazquez, M. A., Ariño, J. & Gancedo, C. (1997). Storage carbohydrates in the yeast Saccharomyces cerevisiae. In Yeast Sugar Metabolism, pp. 285-311. Edited by F. K. Zimmermann. Lancaster, PA: Technomics Publishing.
16. Gounalaki, N. & Thireos, G. (1994). Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response. EMBO J 13, 4036-4041.
17. Hottiger, T., Schmutz, P. & Wiemken, A. (1987). Heat-induced accumulation and futile cycling of trehalose in Saccharomyces cerevisiae. J Bacteriol 169, 5518-5522.
18. Hwang, P. K., Tugendreich, S. & Fletterick, R. J. (1989). Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae. Mol Cell Biol 9, 1659-1666.
19. Kobayashi, N. & McEntee, K. (1990). Evidence for a heat shock factor-independent mechanism for heat shock induction of transcription in Saccharomyces cerevisiae. Proc Natl Acad Sci, USA 87, 6550-6554.
20. Kobayashi, N. & McEntee, K. (1993). Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae. Mol Cell Biol 13, 248-256.
21. Kopp, M., Müller, H. & Holzer, H. (1993). Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae. J Biol Chem 268, 4766-4774.
22. Lewis, L. G., Learmonth, R. P. & Watson, K. (1995). Induction of heat, freezing and salt tolerance by heat and salt shock in Saccharomyces cerevisiae. Microbiology 141, 687-694.
23. Lillie, S. H. & Pringle, J. R. (1980). Reserve carbohydrate metabolism in Saccharomyces cerevisiae: responses to nutrient limitation. J Bacteriol 143, 1384-1394.
24. Londesborough, J. & Vuorio, O. E. (1993). Purification of trehalose synthase from baker's yeast. Its temperature-dependent activation by fructose-6-phosphate and inhibition by phosphate. Eur J Biochem 216, 841-848.
25. Mager, W. H. & de Kruijff, A. J. J. (1995). Stress-induced transcriptional activation. Microbiol Rev 59, 506-531.
26. Marchler, G., Schüller, C., Adam, G. & Ruis, H. (1993). The Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions. EMBO J 12, 1997-2003.
27. Martinez-Pastor, M. T., Marchler, G., Schüller, C., Marchler-Bauer, A., Ruis, H. & Estruch, F. (1996). The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress-response element (STRE). EMBO J 15, 2227-2235.
28. Myers, A. M., Tzagaloff, A., Kinney, D. M. & Lusty, C. J. (1986). Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions. Gene 45, 299-310.
29. Neves, M. J. & François, J. (1992). On the mechanism by which a heat shock induces trehalose accumulation in Saccharomyces cerevisiae. Biochem J 288, 859-864.
30. Ni, H.-T. & Laporte, D. (1995). Response of a yeast glycogen synthase gene to stress. Mol Microbiol 16, 1197-1205.
31. Nwaka, S., Mechler, B., Destruelle, M. & Holzer, H. (1995). Phenotypic features of trehalase mutants in Saccharomyces cerevisiae. FEBS Lett 360, 286-290.
32. Orr-Weaver, T. L., Szostak, J. & Rothstein, R. (1983). Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol 101, 228-245.
33. Panek, A. C., Vania, J. J., Paschoalin, M. F. & Panek, D. (1990). Regulation of trehalose metabolism in Saccharomyces cerevisiae mutants during temperature shifts. Biochimie 72, 77-79.
34. Piper, P. W. (1995). The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap. FEMS Microbiol Lett 134, 121-127.
35. Rose, M. & Botstein, D. (1983). Construction and use of gene fusions lacZ (β-galactosidase) which are expressed in yeast. Methods Enzymol 101, 167-180.
36. Rose, M., Winston, F. & Hieter, P. (1990). Methods in Yeast Genetics: a Laboratory Course Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
37. Rowen, D. W., Meinke, M. & LaPorte, D. C. (1992). GLC3 and GHA1 of Saccharomyces cerevisiae are allelic and encode the glycogen branching enzyme. Mol Biol Cell 12, 22-29.
38. Ruis, H. & Schüller, C. (1995). Stress signaling in yeast. Bioessays 17, 959-965.
39. Schiestl, R. H. & Gietz, R. D. (1989). High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet 16, 339-346.
40. Schüller, C., Brewster, J. L., Alexander, M. R., Gustin, M. C. & Ruis, H. (1994). The HOG pathway controls osmotic regulation of transcription via stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene. EMBO J 13, 4382-4389.
41. Tabata, S. & Hizukuri, S. (1992). Properties of yeast debranching enzyme and its specificity toward branched cyclodextrins. Eur J Biochem 206, 345-348.
42. Thon V. J., Vigneron-Lesens, C, Marianne-Pepin, T., Montreuil, J., Decq, A., Rachez, C, Ball, S. G. & Cannon, J. F. (1992). Coordinate regulation of glycogen metabolism in the yeast Saccharomyces cerevisiae. J Biol Chem 267, 15224-15228.
43. Vandercammen, A., François, J. M., Torres, B. B., Maia, J. C. C. & Hers, H.-G. (1989). Fructose 2,6-bisphosphate and carbohydrate metabolism during the life cycle of the aquatic fungus Blastocladiella emersonii. J Gen Microbiol 136, 137-146.
44. Varela, J. C. S. & Mager, W. H. (1996). Response of Saccharomyces cerevisiae to changes in external osmolarity. Microbiology 142, 721-731.
45. Varela, J. C. S., Praekelt, U. M., Meacock, P. A., Planta, R. J. & Mager, W. H. (1995). The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A. Mol Cell Biol 15, 6232-6245.
46. Vuorio O. E., Kalkinen, N. & Londesborough, J. (1993). Cloning of two related genes encoding the 56-kDa and 123-kDa subunits of the trehalose synthase from the yeast Saccharomyces cerevisiae. Eur J Biochem 216, 849-861.
47. Winderickx, J., De Winde, J. H., Crauwels, M., Hino, A., Hohmann, S., Van Dijck, P. & Thevelein, J. M. (1996). Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252, 470-482.
48. Winkler, K., Kienle, I., Burget, M., Wagner, J. C. & Holzer, H. (1991). Metabolic regulation of the trehalose content of vegetative yeast. FEBS Lett 291, 269-272.