Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5′-phosphosulfate reductase

Journal of Medicinal Chemistry

Volumn 52, Issue 17, 2009, Pages 5485-5495

  Hong, Jiyoung A ^a   Bhave, Devayani P ^a   Carroll, Kate S ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLYLSULFATE REDUCTASE; ENZYME INHIBITOR;

ARTICLE; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; LIGAND BINDING; MOLECULAR RECOGNITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PSEUDOMONAS AERUGINOSA;

CATALYTIC DOMAIN; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; LIGANDS; MAGNESIUM; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PSEUDOMONAS AERUGINOSA; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY;

EID: 69949108708     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900728u     Document Type: Article

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