Tissue kallikrein protects cortical neurons against in vitro ischemia-acidosis/reperfusion-induced injury through the ERK1/2 pathway

Experimental Neurology

Volumn 219, Issue 2, 2009, Pages 453-465

  Liu, Ling ^a,b   Zhang, Renliang ^b   Liu, Kui ^a   Zhou, Houguang ^a   Yang, Xuelian ^a   Liu, Xinfeng ^b   Tang, Min ^c   Su, Jinjin ^a   Dong, Qiang ^a,d  

^a FUDAN UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d FUDAN UNIVERSITY   (China)

Author keywords

Acid sensing ion channels; Acidosis; Cortical neurons; Extracellular signal regulated kinase1 2 signaling pathways; Oxidative stress; Oxygen and glucose deprivation; Tissue kallikrein

Indexed keywords

CASPASE 3; KAILIKANG; MITOGEN ACTIVATED PROTEIN KINASE 1; REACTIVE OXYGEN METABOLITE; TISSUE KALLIKREIN; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ACIDOSIS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANOXIA; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUCOSE; HUMANS; HYDROGEN-ION CONCENTRATION; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PICROTOXIN; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SODIUM CHANNELS; TISSUE KALLIKREINS; URINE;

EID: 69849111675     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.06.021     Document Type: Article

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